Posts

7 days in healthcare (March 11th-17th, 2024)

 

Summary

From the point of view of Biomedicine, a revolutionary blood test stands out that manages to detect colon cancer in early stages and, consequently, reduce the number of deaths. Early diagnosis of this cancer can prevent most deaths, possibly 73% of them. But this requires regular screening in adults. There are two options: colonoscopy every ten years or fecal test every three. Both are unpleasant procedures, the first involving the introduction of a tube into the rectum and the second manipulating the stool itself. But something much simpler is on the horizon: a simple blood test. AI can revolutionize clinical trials, a fundamental basis for the progress of medicine. Just as Moore’s law was known in computing (the information capacity in a circuit grew every two years and at a lower price), in clinical trials in 2012 Eroom’s law was defined, which is just the opposite, since in the 60s In previous years, the number of drugs placed on the market per 1 billion invested was reduced by half every nine years. Half of this time and money was dedicated to clinical trials. AI can disrupt this law by helping to manage clinical trials, including developing protocols, recruiting patients, and analyzing data.

As far as Global Health is concerned, alterations of the nervous system are the most frequent cause of poor health. Neurological diseases such as stroke, dementia and migraine constitute the largest global cause of disease burden. This is related to increased life expectancy. However, if we adjust the data with age, we see that between 1990 and 2021, the number of neurological problems decreased by 27% and the number of deaths by 34%, in that 31-year period. Impressive Egypt success story with hepatitis. In Egypt at the beginning of the 20th century, most of the population worked on farms in contact with the Nile, a source of schistosomiasis, which affected 60% of the population. A treatment was implemented, but without single-use needles. This generated a very high prevalence of hepatitis C, which was reduced in just a decade from 2014. The secret was the free tests and treatment for everyone, with Gilead medication, after having negotiated the price with this company.

In terms of International Health Policy, the NEJM analyzes the effects of vertical integration in American medicine. Vertical integration (purchase of medical practices by hospitals) is unstoppable in the USA. We don’t know the consequences well. In theory it should improve coordination, facilitate the exchange of information and develop economies of scale. But, in practice, what has been seen is an increase in prices. It is urgent to study the consequences of this phenomenon. Macron, after a broad national debate, which included a citizens’ convention, supports the law on the end of life, which must still be approved in Parliament. An impressive debate took place in France on this topic for several months, just the opposite of what happened in Spain where such a transcendental issue was processed as a bill (avoiding the opinions required by the bills) and with hardly any national debate, as if it were a question of modifying the VAT on some product. Agreement in the EU for the regulations on the European Health Data Space, which will allow access to clinical information to any EU patient in all the countries of the Union, as well as the use of this information for research. A great step that, however, will take time to implement, given the very different and heterogeneous development of healthcare digitalization in EU countries.

If we talk about National Health Policy (Spain), the debate continues on the purchase of masks during the pandemic, another example of the more than deficient management of Covid-19 that occurred in Spain. The Minister of Health presents her plans in the Senate. Ambitious battery of health measures: mental health; Public Health Agency; climate change; smoking, sexually transmitted diseases; waiting lists, among other issues. We will see how this agenda progresses, since changes in healthcare are never easy. The health insurers involved in MUFACE (Adeslas, Asisa and DKV) request a renewal of the contract admitting 20% less of the public sector capital without pharmacy, which would mean an increase of 50% on the current capital. They also ask for some system of indexing the capital to the evolution of the public sector. Possibly the extension of the budgets represents an obstacle to the renegotiation of the agreement. Interesting initiative: the Council of Ministers approves a commercial pioneer of advanced therapies with public/private capital, whose promoter and shareholder is the CDTI (50% of the shares), as well as Insud and Rovi (25% each of them). The goal is to develop advanced therapies. It is included in the PERTE and, together, will mobilize 74 million euros.

As for Companies, internationally, recovery of mergers in the pharmaceutical industry in 2023. Psychedelic therapies, in the focus of investors. At the national level, AstraZeneca’s big commitment to Catalonia, where it will invest 1.3 billion until 2027.

Biomedicine

Global Health

International health policy

  • USA
    • The unknown health of the candidates for President in the USA. Everything is based on speculation. There is no official system to know the real health situation of either the presidents or the candidates. An attempt to create an expert body on the topic failed as recently as 2017 (https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)00528-2/fulltext?rss=yes)
    • The Lancet analyzes Biden’s health priorities in the State of the Union address. Commitment to women’s reproductive health; lowering drug prices, expanding Obamacare, preventing gun violence, among the most important priorities (https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)00529-4/abstract?rss=yes)
    • The effects of vertical integration in American medicine. Vertical integration (purchase of medical practices by hospitals) is unstoppable in the USA. We don’t know the consequences well. In theory it should improve coordination, facilitate the exchange of information and develop economies of scale. But, in practice, what has been seen is an increase in prices. It is urgent to study the consequences of this phenomenon (https://www.nejm.org/doi/full/10.1056/NEJMp2313406)
  • France
    • Macron supports the “end of life” bill, which will be discussed by Parliament in May. The term “assisted in dying” is used, rather than euthanasia or assisted suicide, which are considered more controversial. If approved, France will join the few European countries (Switzerland, Holland, Belgium, Spain) that have regulated this issue (https://www.ft.com/content/8129ad50-ae82-4cf9-8b06-cdd196cc57ef)

National health policy

  • Advanced therapies trading company

Companies

7 days in healthcare (April 10th-16th, 2023)

 

Summary

From the point of view of Biomedicine, this week marked the 20th anniversary of the completion (later it turned out not completely) of the Human Genome Project, whose results were presented on April 14, 2003. A project that revolutionized biology and Medicine. Many of the treatments that are now in sight, such as gene editing, or the screening of certain diseases come from the progress of that project.

As far as Global Health is concerned, the criminalization of suicide (considering suicide attempts as a crime subject to fines or imprisonment) is still in force in more than 20 countries. Not so many years ago suicide attempts were decriminalized in advanced societies, as recently as 1966 in England or 1993 in Ireland. Clearly, what these suicidal individuals need is care and treatment.

As for International Health Policy, the United States continues to have problems with the Supreme Court’s decision to annul the FDA’s authorization of an abortion pill, a measure that was later put on hold. The crisis in the British NHS continues, with two important strikes called: nurses and junior doctors.

If we talk about National Health Policy (Spain), the incidence of covid has grown slightly in the last week. Medical and health conflicts continue in various autonomous communities: the Valencian Community, Galicia, the Canary Islands, Madrid and Andalusia. Great news, if confirmed, the arrival of the first publicly funded biomarkers on the SNS. It will start with those related to oncology. A breakthrough in precision medicine. Initiative from Aragon for a debate on health that is intended to be held at the Conference of Presidents. Although everything that represents a debate on health in the highest instances is positive, the lack of ambition of the document proposed from Aragon is truly surprising, where neither the care model nor the management model nor the personnel policy (except in what refers to the planning of professionals), nor many other very relevant things. A real disappointment the document of the Aragonese initiative. The central government supports the Spanish covid vaccine, buying 3.2 million vaccines. FENIN makes some interesting proposals, closely linked to healthcare technology, before the new legislature that is looming.

In the field of Companies, at the international level, KKR promotes the merger of IVI and General Life, to give rise to an infertility giant. At the national level, the creditors of Dentix, a former network of dental clinics, now defunct, accuse KKR of the bankruptcy of this company.

Biomedicine

Global Health

International Health Policy

National health policy

  • FENIN petitions
    • FENIN prepares some requests with 10 points for the new legislature, among them a stable regulatory environment, digital transformation of the SNS, public purchase based on value and the renewal of the health technology park (https://www.fenin.es/resources/press-notes/1011)

Companies

7 days in healthcare (February 6th-12th, 2023)

 

Summary

From the point of view of Biomedicine, vaccines against cancer; precision surgery in lung cancer; the use of bacteriophage viruses against antibiotic resistant bacteria; stem cells for a wide variety of diseases; and micromotor robots, great promise in the development of new advances in medicine.

With regard to Global Health, it should be noted that 839 million people around the world cannot eat with dignity, for various reasons; the magazine Nature calls for a treaty against new pandemics, since it estimates that the covid represented “a catastrophic failure of the international community in achieving solidarity and equity”. The malaria pandemic is still active in more than 30 countries .

Regarding International Health Policy, in the United States the practices of certain pharmaceutical companies to prevent the entry of generics and biosimilars are denounced. International effort in the search for antibiotics to combat bacterial resistance.

If we talk about National Health Policy (Spain), the incidence of the covid has a small rebound, hopefully in a context of falling incidence, although high mortality persists. The Spanish Public Health Agency, whose bill has just been approved, possibly the most important consequence of the covid crisis. The conflict of public health continues, focused on Primary Care. The Constitutional Court recognizes the constitutionality of the abortion law of deadlines. AESEG and BIOSIM request modification of the reference prices and urgent measures along these lines, since many medicines are at the limit of economic viability.

In the field of Companies, at the international level, it should be noted that Sanofi and Merck MSD significantly increase their profits in 2022. At the national level, Quirónsalud announces the start-up of a new hospital in Valencia. For its part, Consentino, a company that had plans to go public, may see its intentions cut short for health reasons, given the high incidence of silicosis among its workforce.

Biomedicine

Global Health

International Health Policy

  • USA

National Health Policy

Companies

7 days in healthcare (March 28-April 3, 2022)

 

SUMMARY

From the point of view of biomedicine, the publication in Science that completes the analysis of the human genome should be highlighted, which seems to open the door to the therapy of various diseases.

As far as Global Health is concerned, polio reappearance in Malawi is of concern.

As for international health policy, problems with the covid-zero policy in China continue, which has led to the confinement of millions of people in Shanghai. As it happens, many older Chinese are unvaccinated, apparently out of fear. The satisfaction of the British public with the NHS falls to the lowest levels in history. At this rate, the UK is going to lose faith in what is said to be their last remaining religion.

If we talk about national health policy (Spain), we are witnessing a new phase of the pandemic, with cases on the rise and hospitalizations on the decline. The Lancet shows that the consumption of opioid analgesics is higher in Spain than in the United States.

In the field of companies, from the international point of view, the plan of the Cleveland Clinic to build a hospital in the center of London, with a large investment of 1 Billion pounds, should be highlighted, which could herald the landing of hospitals Americans in Europe. In our country, the private equity company KKR will pay almost 3 Billion euros for IVI, the largest fertility company in the world, in what is one of the largest operations of its kind in Spain. IMQ approves the sale of shares (50% of the insurer) to SegurCaixa Adeslas, which was already a minority shareholder in the company. Important announcement by Sanitas to launch its fifth hospital in Spain. It will be in Valdebebas, it will come into operation in 2025 and will have 100 beds, 23 of which are for mental health, which is a very innovative element in the Spanish hospital landscape.

BIOMEDICINE

GLOBAL HEALTH

INTERNATIONAL HEALTH POLICY

  • COVID

o Many older Chinese remain unvaccinated, many out of fear (https://www.economist.com/china/2022/04/02/why-so-many-elderly-chinese-are-unvaccinated)

o Lockdown in Shanghai, while covid cases rise throughout China (https://www.theguardian.com/world/2022/mar/28/shanghai-to-lock-down-millions-for-mass-testing-as -chinas-covid-cases-surge)

o The FDA allows a second “booster” for those over 50 (https://www.nytimes.com/2022/03/29/us/politics/second-coronavirus-booster-shot.html)

o The CDC lifts the order that prevented immigration during the pandemic (https://www.nytimes.com/2022/03/30/us/politics/immigration-cdc-biden.html)

  • Other themes

o British public satisfaction with the NHS drops to lowest levels since 1997 (https://www.theguardian.com/society/2022/mar/30/public-satisfaction-with-nhs-sinks-to-lowest- level-since-1997)

o The growth of health spending in the USA was reduced, after the pandemic. In 2021 it rose 4.2%, while in 2020 it had risen 9.7% (https://www.wsj.com/articles/us-healthcare-spending-slowed-in-2021-after-covid-19- surge-11648497601)

NATIONAL HEALTH POLICY (SPAIN)

  • COVID

o New phase of the pandemic: cases on the rise and hospitalizations on the decline (https://elpais.com/sociedad/2022-03-29/espana-entra-en-la-nueva-fase-de-control-de- the-pandemic-with-cases-on-the-rise-and-hospitalizations-on-the-low.html)

  • Other themes

o The flu gets out of control in Spring, it already supposes more hospitalizations than covid in several autonomous communities (https://www.elespanol.com/espana/20220331/descontrola-primavera-supone-ingresos-hospitalarios-covid-ccaa/660934368_0. html)

o The health plan against tobacco will raise its price and will prohibit smoking in cars and terraces, seeking a 25% drop in smoking (https://theobjective.com/sociedad/2022-03-30/sanidad-tabaco-precio- taxes/)

o Spain exceeds the United States in the consumption of opioid analgesics, according to The Lancet (https://www.elindependiente.com/vida-sana/salud/2022/03/31/espana-supera-a-eeuu-en-el -consumption-of-opioid-analgesics-according-to-the-lancet/)

COMPANIES, EMPLOYERS AND OTHER AGENTS IN THE SECTOR

  • International News

o United Health buys home care firm LHC for $5.4 billion (https://www.wsj.com/articles/unitedhealth-to-buy-home-health-firm-lhc-group-for-5-4- billion-11648550701)

o Great bet by the Cleveland Clinic, to build a hospital in central London for 1 Billion pounds (https://www.ft.com/content/c42bc01c-346c-4ae7-a931-4bbf0605e3ec)

o BioNTech returns almost 2 Billion euros to shareholders after the success of the vaccine (https://www.ft.com/content/db1c6786-6707-4d22-bf43-9c7686cbe97b)

o Fresenius acquires mABxscience and Ivenix to accelerate “biopharma” and “medtech” (https://www.plantadoce.com/empresa/fresenius-acquires-mabcience-and-ivenix-to-accelerate-in-biopharma-and-medtech .html)

  • National News

o The EMA begins the evaluation of HIPRA, the Spanish vaccine against covid (https://www.eldiario.es/sociedad/ema-comienza-evaluacion-hipra-vacuna-espanola-covid-19_1_8871634.html)

o The private equity company KKR will pay almost 3 Billion euros for IVI, the Spanish company that is the largest fertility company in the world (https://www.elconfidencial.com/empresas/2022-03-28/kkr-ivi -rma-transition-fertility_3399221/)

o IMQ approves the sale of shares to SegurCaixa Adeslas (https://www.redaccionmedica.com/secciones/privada/los-medicos-de-imq-aproven-la-venta-del-grupo-a-segurcaixa-adeslas-1096 )

o IMED hospitals opens a new polyclinic in Alcoy (https://www.plantadoce.com/empresa/imed-hospitales-abre-una-nueva-policlinica-en-alcoy.html)

o Sanitas will open a new hospital in Madrid, in the Valdebebas neighbourhood, it will be its fifth hospital in Spain and it is expected to open in 2025. It will have 100 individual rooms, 22 dedicated to mental health. Sanitas will be the tenant, the property will be owned by Pryconsa (https://cincodias.elpais.com/cincodias/2022/04/01/companias/1648816602_273605.html)

o LetsGetChecked acquires the Spanish biotechnology company Veritas (https://www.europapress.es/corporate-y-ma/noticia-letsgetchecked-adquiere-100-biotecnologica-espanola-veritas-20220329123245.html)

 

7 days in healthcare (March 21-27, 2022)

 

SUMMARY

From the point of view of biomedicine, the progress in the treatment of breast cancer should be highlighted, according to the article published by the NEJM, with a brake of around 80% of this advanced cancer and makes it disappear in 16%. .

As far as Global Health is concerned, there are undiagnosed cases of tuberculosis (the missing tuberculosis), a disease that continues to have 10 million new cases a year and causes 1.5 million deaths. The Lancet report on what needs to be done to meet target 3.4 of (on non-communicable diseases) of the Sustainable Development Goals. Inequality in covid vaccination and its possible ways to solve it are the subject of an analysis by the NEJM. Concern for the health of the 3.5 million refugees from Ukraine. The low mortality of covid in Africa, a continent that was thought could be devastated by this disease, remains a mystery.

As for international health policy, the debate continues on the covid-zero policy in China, which has achieved great results so far (both in terms of mortality and economics), but it is not known if it will be able to continue with the variant “omicron”. The WHO judges the lifting of COVID measures in Europe too premature, considering that cases are growing, among other countries, in the United Kingdom, Ireland, Greece, France, Italy and Germany.

If we talk about national health policy (Spain), we are witnessing a relaxation of the measures against covid, despite its upward trend in recent days. Arrival of Paxlovid, Pfizer’s treatment for severe cases of covid. The important report published by the Catalan Society of Health Management, with an exceptional team led by Jordi Varela, on the forms of contracting health services from the point of view of value, is very noteworthy. The deans of Medicine react to the Ministry’s announcement of the increase in the “numerus clausus” in medicine by 10%.

In the field of companies, it is worth highlighting the evolution of the purchase of the fertility company IVI, the largest operation carried out by private equity companies in healthcare in Spain and with a company valuation of around 2,500 million euros.

BIOMEDICINE

GLOBAL HEALTH

INTERNATIONAL HEALTH POLICY

NATIONAL HEALTH POLICY (SPAIN)

COMPANIES, EMPLOYERS AND OTHER AGENTS IN THE SECTOR

 

 

7 days in healthcare (February 7-13, 2022)

SUMMARY

From the point of view of biomedicine, to highlight the advances that allow paraplegics to walk, through spinal implants.

Regarding Global Health, it is worth mentioning the WHO warning that the pandemic has threatened the health systems of 90% of the countries; as well as the health problems in Burkina Faso and Afghanistan.

In relation to international health policy, the WHO statement that the pandemic is not over and that more variants are expected should be highlighted. In some countries the restrictions are lifted (United Kingdom, Norway) while in others (Germany) they continue. HERA (the new European Authority for Preparedness and Response to Health Emergencies) begins its steps and will receive a budget of 1,300 million euros in 2022.

In national health policy, we are witnessing a relaxation of the restriction measures, as a consequence of the decrease in the figures of the pandemic (less than 1,500 per 100,000 inhabitants), although these figures are still high and are accompanied by high mortality. Nor is the appearance of new variants ruled out. On the other hand, in the face of loud announcements by the Government, the incorporation of Paxlovid, Pfizer’s medication against serious cases of COVID, is delayed. Work begins for the creation of the State Public Health Surveillance Network, one of the conclusions of the work of the Commission for Social and Economic Reconstruction of the Congress of Deputies of July 3, 2020 (point 19.2), although in the conclusions of the commission there was talk of “urgently implementing” this issue. It is addressed two years after the first death from covid. Also noteworthy is the great concern and mobilizations carried out by the nursing sector. The General Council of Nursing Colleges publishes a Decalogue, whose first point is “Spain without nurses” and the last “Enough of ignoring us”. Spain leads the consumption of anxiolytics, which does not seem like a minor problem.

As far as company news is concerned, mention should be made of the FDA’s delay in approving Pfizer’s vaccine for children under 5 years of age. Also the entry of Nestlé in the field of health, positioning itself in weight control.

BIOMEDICINE

  • Spinal implants allow paraplegics to walk, swim and ride a bike. Breakthrough driven by Grégoire Courtine, a neuroscientist at the Federal Institute of Technology in Lausanne, and Jocelyne Bloch, a neurosurgeon at Lausanne University Hospital. The rupture of the cord prevents the transmission of electrical signals from the brain, which allows the implanted device (The Economist, 12 February 22)
  • There is a lack of evidence that current covid vaccines will produce herd immunity (American Journal of Medicine, February 6, 22)
  • A study analyzes the prevalence of loneliness in 113 countries, as a major health and social problem (BMJ, February 9, 22

GLOBAL HEALTH

  • The WHO warns that more than 90% of the countries have seen their health system threatened by the pandemic (interruptions in services, difficulties in accessing care, problems with emergency care) (La Razón, February 7, 22)
  • The WHO denounces actions by the pharmaceutical industry that make it difficult to bring covid vaccines to Africa. The declaration affects a foundation (kENUP) linked to BioNTech (BMJ, February 9, 22)
  • The armed conflict in the Sahel region (Burkina Faso) endangers the already weak health system (The Lancet, February 12, 22)
  • Afghanistan’s health system is collapsing under stress (NYT, February 6, 22)
  • Ukraine, fears that a health system that had made great progress in recent times is going into crisis due to the possible conflict (The Lancet 12 February 22)

INTERNATIONAL HEALTH POLICY

  • COVID

o The WHO warns that the pandemic is not over and that more variants are expected (ABC, February 12, 22)

o Covid levels remain high in many parts of Europe, but restrictions tend to be lifted (FT, February 11, 22)

o The 1918 flu had devastating effects the third year (Washington Post, February 6, 22)

o Protests against covid restrictions in France and the Netherlands (The Guardian, February 12, 22)

o Waiting lists in England exceed 6 million for the first time (FT, 10 February 22)

o Boris Johnson plans to end the restrictions due to covid a month earlier than planned (The Guardian, February 9, 22)

o China, ready to impose greater confinements in Hong Kong (FT, February 11, 22)

o A study detects that NYC deer are infected by covid (NYT, February 7, 22)

o Seven out of ten vaccines administered in the EU are from Pfizer (El Español, February 11, 22)

o Norway lifts all restrictions against the pandemic (El País, February 13, 22)

o Germany will not lift the restrictions against covid (El Mundo, February 10, 22)

  • Other issues

o HERA (the new European Authority for Preparedness and Response to Health Emergencies) will have a total budget of 1,300 million in 2022 (diariofarma, February 10, 22)

o The EFPIA publishes a white paper on the effectiveness of public procurement of medicines in the EU (EFPIA, February 22)

o It seems that the attempts of the United States government to lower the price of medicines by allowing the negotiation of their prices in Medicare are failing (NEJM, February 9, 22)

NATIONAL HEALTH POLICY (SPAIN)

  • COVID

o The low incidence of 1,500 cases per 100,000 inhabitants in Spain, although with 389 deaths on the last day with official information (La Vanguardia, February 11, 22)

o Delays in the incorporation of Paxlovid, Pfizer’s medication against severe COVID (El Periódico de España, February 11, 22)

  • Political announcements

o Spain begins to create the pandemic alert network, creating the State Public Health Surveillance Network (El Español, 13 February 22)

  • Other issues

o The nursing sector stars in demonstrations throughout Spain (La Razón, February 9, 22)

o Decalogue published by the General Council of Nursing Colleges (CGCE, February, 2022)

o Spain leads the consumption of anxiolytics in Europe, according to the latest report from the Narcotics Control Board (INCB), more than 2.5 million people consume psychotropic drugs daily (La Razón, February 12, 22)

o Spain doubles the number of leprosy cases in 2021 (The Objective, February 7, 22)

o The OMC (Collegiate Medical Organization), against Montero’s campaign on “obstetric violence” (El Español, February 10, 22)

o The Ombudsman intervenes in response to complaints of health cuts to MUFACE officials (La Razón, February 10, 22)

o In a meeting convened by the IMAS Foundation, specialists demand a digital health strategy (Health Act, February 9, 22)

o Cantabria wants to turn Valdecilla into a reference in precision medicine (Sanitary Act, February 10, 22)

COMPANIES, EMPLOYERS AND OTHER AGENTS IN THE SECTOR

  • Important medical bet by Amazon that is revolutionizing the health system in the USA (El Economista, February 12, 22)
  • The FDA puts a brake on the approval of Pfizer’s covid vaccine below 5 years (The Guardian, February 11, 22)
  • Novavax, the fifth vaccine, arrives in Europe the last week of February (diariofarma, February 10, 22)
  • China conditionally approves Pfizer’s treatment Paxlovid (The Guardian, 12 February 22)
  • CEOE: Adriana Bonezzi, new head of the health area (Medical Writing, February 7, 22)
  • Wivi vision. company that evaluates the capabilities of the visual system: agreement with General Óptica to implement it in its network of stores (PlantaDoce, February 8, 22)
  • Vithas joins forces with Genesis Care to launch a cancer center in Madrid (PlantaDoce, February 4, 22)
  • Pfizer more than doubles its profits in 2021, up to 22,000 million dollars (PlantaDoce, February 8, 22)
  • Nestlé Health Science buys Pronokal, positioning itself in the weight loss and control products sector (Diario Médico, February 7, 22)
  • J&J suspends the manufacture of its vaccine (Consalud, February 11, 22)
  • Dependency insurance grows 96% and closes 2021 with 128,000 insured (PlantaDoce, February 7, 22)
  • Durcal relies on Movistar to break into the elderly care segment (PlantaDoce, February 10, 22)
  • Nordic Cap and Amulet enter the bid for the IVI group, Morgan Stanley will receive the non-binding offers before February 23 (CincoDías, February 12, 22)

 

 

7 days in healthcare (January 31-February 6, 2022)

 

SUMMARY

As far as biomedicine is concerned, the report on the value of death by The Lancet stands out; also the development of the nasal vaccine against COVID; the new horizon of transplants, derived from the possibilities of genetic editing of animal organs; and, the revolution that the new cancer vaccines based on mRNA technology may entail.

In terms of global health, the AstraZeneca vaccine is the most widely used worldwide, due to its contribution to COVAX. More than 2,500 million doses have been placed globally.

In international health policy, the most striking is the study by Johns Hopkins University, which minimizes the effectiveness of confinement, which contrasts with previous studies; the 900,000 deaths from COVID in the United States and the 500,000 in India; the WTO continues to request the release of vaccine patents. In Europe, it is worth highlighting the new clinical trial system approved by the European Union and its new approach to cancer.

National health policy continues to be dominated by COVID. The numbers of cases are decreasing, which speaks of the decline of the “sixth wave”. However, deaths are still very high. The announcement that oncological biomarkers will be included in the portfolio of the National Health System is very important. Cancer mapping in Spain presents very striking results, with a high concentration of cancer incidence in certain geographical areas. Subject to study and act.

In company news, the leading role of venture capital companies is notable, with the large operations underway by Sandoz (a generic and biosimilar branch of Novartis) and IVI (a Spanish fertility company). The interest of private equity companies is concentrated around these companies. Also the acquisition of MIR Asturias by CVC and the Alfonso X University. The attempt by Correos to enter pharmaceutical distribution will bring a tail.

BIOMEDICINE

  • Report on the value of death: while in developed countries there is hypertreatment around death, in most countries death occurs without access to basic pain treatment (The Lancet, January 31, 22)
  • The nasal vaccine may be better for successive doses. There are a dozen such vaccines in development in phase 3 trials (NYT, February 2, 22)
  • The “stealth” variant (stealth) does not generate alarm, but it can slow down the decline in the number of cases (NYT, January 31, 22)
  • The sub-variant “ómicron” BA.2, more contagious than the original (FT, 31 January 22)
  • The new variant BA.2, already present in 57 countries, according to the WHO (FT, February 3, 22)
  • New variant of the HIV virus, discovered in the Netherlands (FT, February 3, 22)
  • Genetic editing of pig hearts: a new horizon for transplants (FT, February 2, 22)
  • Cancer vaccines: the new mRNA revolution (El País, Vozpópuli, February 4, 22)
  • Amidst the wide debate on abortion, a simple pill seems the most viable option (The Economist, 5 February 22)

GLOBAL HEALTH

  • AstraZeneca, the most distributed vaccine through COVAX, has already given 2,500 million doses worldwide (ConSalud, January 31, 22)
  • Humanitarian groups denounce that sanctions against Mali may have very adverse health consequences (The Lancet, February 5, 22)

INTERNATIONAL HEALTH POLICY

  • COVID

o A study by Johns Hopkins University (Applied Economics Studies magazine) questions the effectiveness of confinement in reducing mortality, which contrasts with the analysis published in Nature in June 2020, which estimates that three million deaths have been prevented in Europe by confinement, 450,000 in Spain (El Independiente, February 3, 22)

o The UK approves the Novavax vaccine (FT, 3 February 22)

o The American army begins to fire its members who refuse the vaccine (The Guardian, February 2, 22)

o The New Zealand border will be reopened in phases from the end of February, the Prime Minister announces (The Guardian, 2 February 22)

o The United States reaches 900,000 deaths from COVID (The Guardian, February 4, 22)

o India exceeds 500,000 deaths from COVID (The Guardian, February 4, 22)

o Europe facing a “long period of tranquility” in the pandemic, says the WHO, due to the lesser severity of the “ómicron” variant, the high percentages of immunization and the good weather (The Guardian, February 3, 22)

o The WTO (World Trade Organization) wants an agreement to release vaccine patents this month (El Español, February 1, 22)

o The German Vaccine Commission recommends the fourth dose for vulnerable and health groups (El País, February 3, 22)

o Beijing seals off several communities for two cases of COVID (The Guardian, January 31, 22)

o The COVID vaccine is already mandatory in Austria, with a great social fracture (Expansión, February 5, 22)

  • Other issues

o New clinical trial system in Europe, which Farmaindustria sees as an opportunity (diariofarma, February 1, 22)

o The EU will act against inequalities against cancer (ConSalud, February 3, 22)

NATIONAL HEALTH POLICY (SPAIN)

  • COVID

o The sixth wave is being left behind, the cases and hospitalizations are slowing down, although not the deaths that already exceed 6,000 since November (El País, February 5, 22)

o The mask outdoors will no longer be mandatory from next Thursday (El País, February 4, 22)

o Health has not yet closed the purchase of 344,000 doses of Paxlovid (El Español, February 3, 22)

o The AEM authorizes the HIPRA vaccine to go to phase 3 of clinical trials (The Objective, February 1, 22)

  • Political ads

o The new public health center, affected by the decentralization of public offices (diariofarma, February 1, 22)

o The approval of oncological biomarkers, announced as a pending objective of the expansion of the NHS portfolio (diariofarma, February 1, 22)

o The Minister of Health says that the Anti-Tobacco Law needs to be updated (ConSalud, February 4, 22)

  • Other issues

o 27% of pharmaceutical innovations approved in 2021, subject to special financing conditions (diariofarma, February 1, 22)

o Access to new cancer drugs takes more than 19 months in Spain, while in Germany it takes two months, according to doctors and patients (La Vanguardia, February 2, 22)

o Health plan to make rural pharmacies more viable (ConSalud, January 28, 2022)

o The private e-prescription is consolidated (diariofarma, February 2, 22)

o The cartography of cancer in Spain has been published, with very striking results, according to the “Atlas of Cancer Mortality in Portugal and Spain” (El Periódico de España, February 5, 22)

COMPANIES, EMPLOYERS AND OTHER AGENTS IN THE SECTOR

  • American pharmaceutical companies (J&J and three of the largest drug distributors in the United States) agree to pay 590 million dollars to Native Americans for the opioid crisis (El País, February 1, 22)
  • Pharmaceutical cold distribution, new Correos service (Redacción Médica, February 2, 22)
  • Pfizer-Biontech requests authorization from the FDA for the approval of the vaccine for children under 5 years of age (El País, February 1, 22)
  • Private equity companies consider offers of more than 25,000 million dollars for the generics unit of Novartis, Sandoz, Blackstone, Carlyle and EQT, among the most interested (FT, February 1, 22)
  • KKR, CVC, Permira, Bain, Carlyle and PAI outline their bids to take over the fertility company of Valencian origin IVI, the bids range from 1,500 million euros (CincoDías, January 31, 22)
  • Atrys enters the continuous market, as of February 7 (PlantaDoce, February 3, 22)
  • Sanitas gains ground and plans to open 7 rehabilitation centers in 2022 (PlantaDoce, February 1, 22)
  • Adeslas and Caixabank extend their agreement in the Bankia network for 650 million euros (CincoDías, January 27, 22)
  • MIR Asturias acquired by CVC and Alfonso X University (La Nueva España, February 3, 22)
  • Quirón acquires Clínicas Vida and strengthens its care network in Tenerife (PlantaDoce, January 28, 22)
  • Vitaldent expands throughout Andalusia and opens a new clinic in Benalmádena (PlantaDoce, February 3, 22)
  • Group 5 opens a residence for serious mental disorders in Madrid (PlantaDoce, February 3, 22)
  • Prim is reinforced with the purchase of Herbitas laboratories (Expansión, February 4, 22)
  • Pharmamar leads a consortium of companies for the development of advanced therapies (El Economista, February 3, 22)