7 days in healthcare (May 6th-12th, 2024)
Summary
Biomedicine
- The enigma of the brain: The Economist highlights the enigma that the brain represents, made up of hundreds of trillions of cells that generate precise electrical impulses, which influence thoughts, memory and emotions, recommending 8 books on the subject, of which two They refer to the contributions of Ramón y Cajal, whom he compares with Darwin and Pasteur. The brain will be the focus of scientific advancement in the next 30-50 years.
- CAR-T therapies, beyond blood cancer: Experiments in mice with this therapy manage to improve survival in brain, pancreas and lung tumors.
Global Health
- One Health, from slogan to action plan: A group of European agencies, led by the ECDC, which includes the EMA, manage to transform the idea of One Health into an action plan, establishing five major strategic objectives.
- The WHO Pandemic Treaty advances: WHO member states are about to reach an agreement on the response to pandemics, an agreement that, in principle, should be approved in May 2024.
International health policy
- The great problem of hospital infections: The ECDC releases a report that shows that more than four million Europeans contract infections each year due to hospital admissions. This confirms the old criterion of hospital ethics: “Do not admit anyone unless it is strictly necessary and, if admitted, let them be in the hospital for the shortest possible time.”
- Whooping cough is increasing in Europe: The ECDC publishes a report that warns of the increase in whooping cough cases in the European Union.
National Health Policy (Spain)
- The government proposes new benefits in the SNS: condoms, sun creams and glasses: It is more than doubtful that with the financial tensions of an already very generous system (wide portfolio of services with hardly any co-payment), introducing new benefits without a debate in depth is a priority. Arguably, this has more to do with the political use of the system than with health policy.
- The Catalan Generalitat will supervise the use of Catalan in its hospitals: CatSalut publishes exhaustive 9-page instructions on the subject. Same comment regarding political use of the system and health policy.
- 18 patients die every day in Spain from hospital infections: According to a large study presented at the congress of the European Society of Clinical Microbiology and Infectious Diseases, four times more than those who died from traffic accidents. More than half of infections are considered preventable.
- Workplace accidents increase: 56% in ten years. Both workplace accidents and the number of deaths increase in this period (452 deaths in 2012; 716 in 2022).
- Innovative medicines take more than 800 days to reach patients in Spain: 621 days pass from the time a therapy is authorized by the European Commission until the Ministry of Health includes it in the list of approved treatments, according to the consulting firm. IQVA. To this figure we must add seven months or a year, depending on autonomy, until the treatment reaches the patients’ hands. In total, around 830 days.
Companies
- International
- The reengineering of addiction and the tobacco industry: For decades the tobacco industry has manipulated the design and composition of cigarettes to its benefit. Researchers and policy actors should be prepared to anticipate the tobacco industry’s response, given its long history of exploiting regulatory loopholes, according to an extensive article in the New England Journal of Medicine.
- BioNTech looks to the future: It hopes that 2026 will be its debut in oncology with mRNA vaccines against cancer.
- National
- Vithas has a quality policy: The International Joint Commission accredits the Vithas Hospital of Almería, the fourth accredited hospital in this group.
- Sanitas leaves the Manises hospital: Public reversal in this hospital. Sanitas leaves with discretion and elegance and leaving behind great management. How these things should be done.
- Mutua Madrileña warns that Adeslas could leave MUFACE: Mutua Madrileña (50.01% shareholder of Adeslas, along with CaixaBank) warns that it will leave MUFACE if the government does not clearly improve conditions. The three companies that participated in the MUFACE model in these three years (Adeslas, Asisa and DKV) lost 600 million in this period. Logically, the possible departure of Adeslas would be a definitive death blow for the MUFACE model.
Biomedicine
- The Economist highlights the enigma that the brain represents, made up of hundreds of billions of cells that generate precise electrical impulses, which influence thoughts, memory and emotions, recommending 8 books on the subject, of which two refer to the contributions by Ramón y Cajal, which he compares to Darwin and Pasteur (https://www.economist.com/the-economist-reads/2024/05/03/these-books-reveal-why-the-brain-is-the-biggest-mystery-of-all?utm_medium=cpc.adword.pd&utm_source=google&ppccampaignID=18151738051&ppcadID=&utm_campaign=a.22brand_pmax&utm_content=conversion.direct)
- The brain will be the focus of scientific progress in the next 30-50 years (https://www.diariomedico.com/medicina/neurologia/cerebro-sera-protagonista-avances-cientificos-proximos-30-50-anos.html )
- A new antibiotic buys time for medicine in the endless fight against superbacteria, which cause 1.2 million deaths in the world. The European Commission has just authorized the marketing of a new antibiotic to combat these bacteria. This is Emblaveo, developed by Pfizer and Abbie. Conversations will be opened to incorporate this medicine into Spanish public health (https://elpais.com/sociedad/2024-05-10/un-nuevo-antibiotico-da-tiempo-a-la-medicina-en-la-interminable-fight-against-superbacteria.html)
- A hallucinogen from the venom of the bufo toad shows potential to treat mental disorders (https://elpais.com/salud-y-bienestar/2024-05-09/un-alucinogeno-del-veneno-del-sapo-bufo-muestra-potential-to-treat-mental-disorders.html)
- Green light for the first non-invasive test for the detection of colorectal cancer. The FDA has given the green light to ColoSense, a non-invasive stool RNA test for the detection of colorectal cancer (https://www.larazon.es/salud/luz-verde-primera-compra-invasiva-deteccion-cancer-colorectal_20240511663ec43dc0b95c00018027eb.html)
- The revolutionary CAR-T cell therapy seeks to make its way beyond blood cancer. Experiments in mice with this therapy manage to improve survival in brain, pancreas and lung tumors (https://elpais.com/salud-y-bienestar/2024-05-08/la-revolucionaria-terapia-cellular-car-t-seeks-to-open-step-beyond-blood-cancer.html)
- The Lancet Editorial: Improving the quality of life of patients with motor neurone disease. This incurable neurodegenerative disease may benefit from a therapy based on acceptance, mindfulness, motivation and behavioral changes (https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)00972-3/fulltext?rss=yes)
- Hearing restoration in a British child with gene therapy (https://www.theguardian.com/science/article/2024/may/09/uk-toddler-has-hearing-restored-in-world-first-gene-therapy-trial#:~:text=A%20British%20toddler%20has%20had,new%20era%20in%20treating%20deafness.)
Global Health
- Action plan of a working group of five European agencies on One Health. A set of European agencies, led by the ECDC, which includes the EMA, managed to transform the idea of One Health into an action plan, establishing five major strategic objectives (https://www.ecdc.europa.eu/en/publications-data/cross-agency-one-health-task-force-framework-action). Access to the 2024-2026 plan: https://www.ecdc.europa.eu/sites/default/files/documents/cross-agency-one-health.pdf
- Article from the New England Journal Medicine, about a law on Global Health for a safer and fairer world. In relation to the pandemic treaty (https://www.nejm.org/doi/abs/10.1056/NEJMms2403267)
- Organization for the control of pandemic financing (https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)00971-1/abstract?rss=yes)
- The member states of the WHO, on the verge of reaching an agreement on the response to pandemics, an agreement, which, in principle, should be approved in May 2024 (https://www.lemonde.fr/planete/article/2024/05/10/les-etats-membres-de-l-organisation-mondiale-de-la-sante-peinent-a-s-accorder-sur-la-reponse-aux-pandemies_6232546_3244.html#:~:text=Vendredi%2010%20mai%2C%20les%20délégués,et%20de%20réponse%20aux%20pandém)
- Environmental changes are driving human, animal and plant diseases. Biodiversity loss, global warming, pollution, and the spread of invasive species make infectious diseases more dangerous to organisms around the world (https://www.nytimes.com/2024/05/08/health/environment-climate-health.html#:~:text=61-,Environmental%20Changes%20Are%20Fueling%20Human%2C%20Animal%20and%20Plant%20Diseases%2C%20Study,to%20organisms%20around%20the%20world.)
International health policy
- USA
- Why poor bird flu monitoring puts dairy workers at risk (https://www.nytimes.com/2024/05/09/health/bird-flu-diaries-farmworkers.html#:~:text=Farmworkers%20have%20been%20exposed%20to,about%20who%20may%20be%20infected.)
- The USA launches to declassify marijuana as “dangerous” and the sector experiences increases of up to 100% (https://www.eleconomista.es/mercados-cotizaciones/noticias/12804908/05/24/eeuu-se-lanza-to-declassify-marijuana-as-dangerous-and-the-sector-experiences-rises-of-upto-100-in-2024.html#:~:text=The%20sector%20national%20in%20su,in%20USA%20es%20something%20extr)
- United Kingdom and the National Health Service
- Why mental health in the UK is so poor (https://www.theguardian.com/commentisfree/article/2024/may/10/britain-mental-health-society-neoliberalism-politicians)
- Obesity and low productivity in the UK go hand in hand (https://www.ft.com/content/d6f2354b-8fd4-434b-bbb2-f5828f9ecc42)
- France
- A new vision of mental health is proposed, with the need to remove psychiatry from the hospital (https://www.lemonde.fr/idees/article/2024/05/10/une-autre-vision-de-la-sante-mentale-est-necessaire-il-faut-sortir-la-psychiatrie-de-l-hopital_6232443_3232.html#:~:text=une%20psychiatrie%20sinistrée%20»-,Une%20autre%20vision%20de%20la%20santé%20mentale%20)
- European Union
- ECDC: More than four million Europeans contract infections every year due to hospital admissions (https://www.ecdc.europa.eu/en/news-events/each-year-43-million-patients-hospitals-eueea-are-affected-healthcare-associated). Access to the original document: https://www.ecdc.europa.eu/sites/default/files/documents/healthcare-associated-point-prevalence-survey-acute-care-hospitals-2022-2023.pdf
- ECDC: Increase in pertussis cases in the European Union (https://www.ecdc.europa.eu/en/news-events/increase-pertussis-cases-eueea-infants-under-six-months-age-highest-risk). Access to the original document: https://www.ecdc.europa.eu/sites/default/files/documents/Increase%20in%20pertussis%20cases%20in%20the%20EU-EEA%20-%20May%202024%20FINAL.Pdf
National health policy
- Central government initiatives
- The Government creates the Health Care Committee (https://gacetamedica.com/politica/sanidad-crea-un-comite-de-cuidados-de-salud-con-alda-recas-y-mayte-moreno-al-forehead/)
- New benefits are proposed in the SNS: condoms, sun creams and glasses (https://www.elespanol.com/invertia/observatorios/sanidad/20240509/ministerio-sanidad-estudia-ofrecer-crema-solar-gratuita-determinados-places-publicos/853914722_0.html) (https://www.eldebate.com/podcast/20240509/nuevo-gasto-sanidad-10-millones-preservativos-crema-gratis_195817.html#:~:text=La%20ministra%20de%20Sanidad%2C%20Mónica,propuesta%20de%20sanidad%3A%20crema%20gratis.) (https://www.redaccionmedica.com/secciones/ministerio-sanidad/la-sanidad-espanola-sumara-las-gafas-to-his-public-portfolio-in-2025-7827#:~:text=The%20Ministry%20of%20Sanidad%20willincorporate,State%20of%20branch%2C%20Javier%20Padilla.)
- Profound changes are proposed in the Framework Statute (https://www.redaccionmedica.com/secciones/ministerio-sanidad/garcia-presenta-a-la-negociadora-del-profundo-cambio-del-estatuto-marco-5972)
- The Interterritorial Council of the SNS must adapt its operation to a binding sectoral conference (https://diariofarma.com/2024/05/05/el-cisns-debera-adaptar-su-reglamento-al-de-una-conférence-sectorial-binding#)
- Initiatives and news from the autonomous communities
- The Generalitat Catalana will supervise the use of Catalan in its hospitals (https://theobjective.com/sanidad/2024-05-10/generalitat-supervisara-uso-catalan-hospitales-vigilantes-linguisticos/). Access to the original document entitled “Mesures directed to promote the compliment of the linguistic rights of the users and patients of the comprehensive public health system of Catalonia (SISCAT)”: https://scientiasalut.gencat.cat/handle/11351/11446
- The Generalitat Valenciana rules out subrogating the staff of the Torrevieja hospital laboratory in the reversion (https://alicanteplaza.es/sanidad-descarta-subrogar-a-la-plantilla-del-laboratorio-del-hospital-de-torrevieja#:~:text=TORREVIEJA.,I%20can%20jump%20the%20ley%22.)
- Hospital infections
- 18 patients die every day in Spain from hospital infections, according to a large study presented at the congress of the European Society of Clinical Microbiology and Infectious Diseases, four times more than those who die from traffic accidents. More than half of infections are considered preventable. The data come from EPINE, an epidemiological surveillance system (https://elpais.com/sociedad/2024-05-06/18-pacientes-mueren-cada-dia-en-espana-por-infecciones-adquiridas-en-los-hospitals.html)
- Work accidents
- Workplace accidents have increased by 56% in ten years. Both workplace accidents and the number of deaths have increased in this period (452 deaths in 2012; 716 in 2022) (https://www.elespanol.com/ciencia/salud/20240510/batalla-perdida-accidentes-laborales-espana-deaths-increase-only-years/853914871_0.html#)
- Nurse transfers
- More than 8,000 nurses moved to Spain in search of job improvements, of which 1,473 to another country (https://elpais.com/sociedad/2024-05-09/mas-de-8000-enfermeras-se-trasladaron-in-2023-in-search-of-better-working-conditions.html)
- Ministry of Health and FACME
- The Ministry of Health and FACME will collaborate on training programs and agree to collaborate in updating the MIR programs (https://www.diariomedico.com/medicina/medico-joven/mir/sanidad-facme-acuerdan-agilizar-actualizacion-programs-mir.html)
- Health “privatization”
- Some entities, the Federation of Associations for the Defense of Public Health (FADSP), consider that Madrid and the Balearic Islands are the communities that have made the most progress in health privatization. This is the tenth report on this topic from this entity. (https://elpais.com/sociedad/2024-05-08/la-privatizacion-de-la-sanidad-sigue-avanzando-con-madrid-y-baleares-a-la-head.html#). The FADS reports have been highly criticized for their methodology by different voices, such as the FACME, among others: https://www.redaccionmedica.com/secciones/sanidad-hoy/los-informes-de-fadsp-senalados-no-are-scientifically-supported–2187
- Transplants
- Live donation, one of the challenges of the Spanish transplant model. Despite the success of transplants in Spain, our country needs to increase transplants from living donors, for which we have worse data than other European countries (https://www.epe.es/es/sanidad/20240510/aumentar-donacion-vivo-grandes-retos-spain-transplants-102150114)
- Delays innovative medications
- Innovative medicines take more than 800 days to reach the hands of patients in Spain. 621 days pass from when a therapy is authorized by the European Commission until the Ministry of Health includes it in the list of approved treatments, according to the consulting firm IQVA. To this figure we must add seven months or a year, depending on autonomy, until the treatment reaches the patients’ hands. In total, around 830 days (https://www.eleconomista.es/salud/noticias/12806739/05/24/-los-nuevos-medicamentos-tardan-1000-dias-en-llegar-a-manos-de-the-patients.html)
Companies
- International News
- New England Journal of Medicine article: Reengineering addiction: changes in the tobacco industry. For decades the tobacco industry has manipulated the design and composition of cigarettes to its benefit. Researchers and policy actors must be prepared to anticipate the tobacco industry’s response, given its long history of exploiting regulatory loopholes to maintain profit (https://www.nejm.org/doi/full/10.1056/NEJMp2314800)
- AstraZeneca withdraws its covid vaccine worldwide, citing vaccine oversupply (https://www.theguardian.com/business/article/2024/may/08/astrazeneca-withdraws-covid-19-vaccine-worldwide-citing-surplus-of-newer-vaccines#:~:text=In%20a%20statement%2C%20AstraZeneca%20said,longer%20being%20manufactured%20or%20supplied.)
- Novavax grows rapidly with a license with Sanofi to increase sales of post-pandemic vaccines (https://www.bloomberg.com/news/articles/2024-05-10/sanofi-signs-1-2-billion-vaccine-licensing-deal-with-novavax?embedded-checkout=true)
- Sales of anti-obesity drugs from NovoNordisk and Lilly exceed 7,369 million euros in a single quarter (https://www.elespanol.com/invertia/observatorios/sanidad/20240510/ventas-farmacos-obesidad-novo-nordisk-lilly-exceed-meur-only-quarter/853164873_0.html#:~:text=From%20made%2C%20%20sales%20,27,810%20million%20%20danishcrowns).)
- BioNTech looks towards 2026 for its debut in oncology with mRNA vaccines against cancer (https://theobjective.com/economia/2024-05-10/biontech-debut-oncologia-vacunas-arnm-cancer/)
- BioNTech loses 315 million in the first quarter due to the drop in anti-covid vaccines (https://www.plantadoce.com/empresa/biontech-pierde-315-millones-en-el-primer-trimestre-por-la-fall-of-the-anti-covid-vaccines#:~:text=PlantaTwelve-,BioNTech%20loses%20315%20million%20in%20the%20first%20quarter%20for%20the,59%2C1%20million%20of%20euros )
- Fresenius sells its rehabilitation business to PAI Partners for 853 million euros (https://www.plantadoce.com/empresa/fresenius-vende-a-pai-partners-su-negocio-de-rehabilitacion-por-853-million-euro#:~:text=The%20German%20multinational%20has%20arrived,and%20management%20of%20healthcare%20facilities.)
- National
- Proclinic Group reached a turnover record of 256 million euros in 2023 (https://www.eleconomista.es/actualidad/noticias/12806222/05/24/proclinic-group-bate-record-crece-un-16-and-exceeds-256-million-billing.html#:~:text=Good%20results%20for%20Proclinic%20Group,%20220%20million%20of%20euros.)
- The Joint Commission International accredits the Vithas Hospital of Almería, the fourth accredited hospital of this group (https://www.diariomedico.com/medicina/empresas/joint-commission-international-acredita-calidad-asistencial-hospital-vithas-almeria.html)
- Boehringer Ingelheim invests 62 million euros in R&D&i in Spain, 36% more (https://www.plantadoce.com/empresa/boehringer-ingelheim-invierte-62-millones-de-euros-en-idi-in-espana-un-36-mas)
- Sanitas leaves the Manises hospital, which increases by 400 employees with the public reversion (https://www.eleconomista.es/salud/noticias/12801930/05/24/sanitas-deja-el-hospital-de-manises-which-goes-from-1800-to-2200-employees-with-the-public-reversion.html)
- Mutua Madrileña (50.01% shareholder of Adeslas, along with CaixaBank) warns that it will leave MUFACE if the government does not clearly improve conditions. The three companies that participated in the MUFACE model in these three years (Adeslas, Asisa and DKV) lost 600 million in this period (https://cincodias.elpais.com/companias/2024-05-10/mutua-amenaza-con-leave-muface-if-the-government-does-not-clearly-improve-conditions.html#)
- Grifols overcomes the Chinese government procedures for the sale of Shanghai Rass for 1,629 million (https://www.eleconomista.es/salud/noticias/12800785/05/24/grifols-supera-los-tramites-gubernamentales-chinos-para-the-sale-of-shanghai-raas-for-1629-million.html)