7 days in healthcare (July 24th-30th, 2023)
Summary
From the point of view of Biomedicine, the mRNA vaccine for cancer and regenerative medicine seem to be the great promises in medical advances.
As regards Global Health, The Lancet dedicates an editorial to the need for a broader vision of women’s health, beyond maternal health. The most prevalent disease problems in women are the same as in men, but need insight into specific, poorly understood risks.
As for International Health Policy, the battle continues in the United States for the application of the new pharmaceutical policy that allows Medicare to negotiate the price of drugs, something that until now had been banned. This negotiation will begin in 2024 and it is expected that on September 1, 2023 the medicines on which it will be negotiated will be known. In a movement that seems to be ahead of events, several pharmaceutical companies (Janssen, Merck, Astellas Pharma and BMS) file a lawsuit against the American government. Apart from other possible considerations, it seems difficult to maintain that the price of medicines is much higher in the United States than in other countries, and not only in developing countries, but also in Europe. In the United Kingdom, the British Medical Journal focuses on the financing of pharmaceutical and medical technology companies to British scientific societies. For this, more transparency is required.
If we talk about National Health Policy (Spain), the political changes derived from the regional elections establish a new configuration of the Interterritorial Council, which will be numerically dominated by the PP (which will count, including the Canary Islands Coalition) 12 seats in the Council, by 3 of the PSOE (Castilla-La Mancha, Navarra, Asturias), 1 from the PNV (Basque Country) and 1 from ERC (Catalonia). The Radar Healthcare organization publishes a new ranking of healthcare systems and awards Spain a very favorable position in terms of quality. In general, these types of rankings must be looked at with a magnifying glass and consider the type of indicators analyzed and another series of circumstances. A biased and unprofessional interpretation of the international rankings on the Spanish health system has meant, in practice, a brake on the reforms. If we are so well, why reform anything? It is known that Spain is one of the OECD countries that devotes less public funding to dental care. What we did not know and what is now clear is that it has even dropped very significantly in the last decade, going from 5,245 million euros in 2010 to 3,681 in 2020. It seems clear that Spain, which globally has organized vaccination against covid very well However, it has failed to develop a vaccine: the HIPRA vaccine was delayed much longer than expected and the announced intranasal vaccine no longer even has a release date. It is difficult to compete with vaccines that appear less than a year after the onset of the disease, as has happened in the case of covid, with long development of vaccines that take years.
In the field of Companies, internationally, the president of Novartis (company of European origin) says that the price reform in the United States of medicines represents a threat to Public Health. At the national level, it is worth noting that spending on biosimilars has exceeded 1 billion euros in 2022, due to the fact that the patent for several biological drug molecules has expired and biosimilars have appeared.
Biomedicine
- Statements by the Prince of Asturias Award in 2004, Tony Hunter: “the most exciting thing in cancer treatment today is the possibility of designing an mRNA vaccine” (https://www.diariomedico.com/medicina/oncologia/quiza-lo-most-exciting-currently-in-cancer-treatment-is-the-possibility-of-designing-an-mRNA-vaccine.html)
- Regenerative medicine, part of the future. It is based on the natural ability of the human body to regenerate and repair damaged tissue. Techniques such as cell therapy, gene therapy, tissue engineering and growth factor therapy are used. The target are chronic, neurodegenerative, autoimmune pathologies or certain types of cancer (https://www.consalud.es/profesionales/medicina-regenerativa-imitar-naturaleza-aumentar-calidad-vida-pacientes_132812_102.html)
Global Health
- The Lancet Editorial: A broader view of women’s health. Apart from maternal health problems, the root causes of health problems in women are cardiovascular disease, cancer and mental problems, the same as in men, but with poorly understood specific risks (https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)01570-2/fulltext)
- Climate change and malaria. The Intergovernmental Panel on Climate Change estimates that between 51-62 million people will be at risk of malaria in Africa by around 2030 due to global warming (https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)01569-6/fulltext#:~:text=“The%20links%20between%20malaria%20and,RBM%20Partnership%20to%20End%20Malaria.)
- The WHO warns of an outbreak of MERS-CoV in the United Arab Emirates (https://gacetamedica.com/investigacion/la-oms-alerta-de-un-caso-de-mers-cov-en-emiratos-arabes-united/#:~:text=The%20World%20Organization%20of%20la,Dhabi%20(United%20Arab%20Emirates).)
- The WHO warns that 20,000 people drown each year in Europe (https://www.consalud.es/pacientes/oms-advierte-20000-personas-mueren-ahogadas-anualmente-en-europa_132704_102.html#)
International Health Policy
- COVID19
- Weekly covid report published by WHO, 27 July 2023. While five WHO regions have shown a decline in cases and deaths, the Western Pacific region has shown both an increase in cases and deaths Covid continues being a major threat. Maintaining surveillance and reporting is critical (https://reliefweb.int/report/world/covid-19-weekly-epidemiological-update-edition-151-published-13-july-2023)
- USA
- Pharmaceutical companies sue to avoid lowering the price of medicines. Medicare (the most important American public system) will be able to negotiate the prices of medicines from 2024. On September 1, the medicines whose prices will be negotiated will be known. The companies that will sue the US government are Janssen, Merck, Astellas Pharma and BMS. (https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)01568-4/fulltext)
- Fentanyl (a very powerful synthetic opioid, which can be legally used as a pain reliever) spreads the opioid crisis in large American cities (https://www.economist.com/united-states/2023/07/27/fentanyl-is-spreading-the-opioid-crisis-into-americas-big-cities)
- War between pharmaceutical companies and Biden over the price of medicines and mergers (https://www.elespanol.com/invertia/observatorios/sanidad/20230725/guerra-farmaceuticas-biden-precios-medicamentos-fusiones-punto-mira/781421944_0.html)
- United Kingdom and National Health Service
- One in five adults will be living with a major disease by 2040, according to a report by The Health Foundation (https://www.bmj.com/content/382/bmj.p1711)
- Medical societies receive millions of pounds from pharmaceutical and medtech companies. Critics say transparency is not enough (https://www.bmj.com/content/382/bmj.p1658)
- 38 million patients wait over 14 days to see a GP (primary physician) in England (https://www.theguardian.com/society/2023/jul/23/patients-wait-over-14-days-gp-appointments-england-despite-government-pledge#:~:text=More%20than%2038%20million%20patients,weeks%20of%20booking%20a%20consultation.)
- Problems in cancer care due to delays in England and Wales (https://www.theguardian.com/society/2023/jul/29/revealed-how-hidden-delays-blight-cancer-care-in-england-and-wales)
- Canada
- Montreal, affected by the massive consumption of fentanyl (https://www.lemonde.fr/international/article/2023/07/26/montreal-touchee-de-plein-fouet-par-la-consommation-destructrice-de-fentanyl_6183410_3210.html#:~:text=Le%20fentanyl%2C%20mélangé%20à%20d,doublé%20par%20rapport%20à%202022.)
- European Union
- Towards a European Health Union. The EU Health Ministers meet in Las Palmas, within the framework of the European Presidency of Spain. Progress is being made in the European Health Union, which will include a European Medicines Union (https://www.diariomedico.com/medicina/politica/hacia-una-union-europea-de-la-salud.html)
National health policy
- Changes in the Interterritorial Council
- Changes in the political sign of the autonomous communities completely modify the political weights in the Interterritorial Council. The popular ones will have 12 seats (with the Canary Islands Coalition), compared to 3 for the socialists (Castilla-La Mancha, Navarra and Asturias), 1 for the PNV (Basque Country) and 1 ERC (Catalonia) (https://gacetamedica.com/opinion/a-new-territorial-council-of-the-sns/)
- New ranking of health systems, which gives Spain a good position
- According to this ranking, it is the third in Europe and fifth in the world in terms of quality (https://www.redaccionmedica.com/secciones/sanidad-hoy/la-sanidad-espanola-esta-entre-las-mejores-del-mundo-in-quality-care-2251#). To view the original Radar Healthcare article: https://radarhealthcare.com/news-blogs/healthcare-mapped-report/
- Public healthcare
- Public spending on oral health in Spain is reduced by 30% in a decade. Expenditure per inhabitant has gone from 113 euros to 78 euros, reaching 3.68 billion euros in 2020, compared to 5.24 in 2010 (https://www.consalud.es/dentalia/pacientes-casos/gasto-en-salud-bucodental-in-spain-is-reduced-30-in-ten-years_132831_102.html#)
- Response to the judgment of the National Court on the setting of the price of medicines
- Health responds to the sentence of the Hearing that annuls its drug approval plan. Study to appeal the ruling (https://www.diariomedico.com/farmacia/industria/sanidad-responde-la-sentencia-de-la-audiencia-que-anula-su-plan-de-approvacion-de-farmacos.html)
- Spanish Medicines Agency
- The Agency publishes its strategic plan for the next four years (https://medicinaresponsable.com/actualidad-sanitaria/aemps-plan-estrategico)
- Spain fails in covid vaccines
- From HIPRA to the already forgotten intranasal (https://www.eldebate.com/sociedad/20230724/el-fracaso-de-las-vacunas-espanolas-contra-la-covid-desde-la-prometida-hipra-hasta-the-forgotten-intranasal_129828.html)
- Laboratory against pandemics
- The government (Ministry of Science) awards its maximum biological security pandemic laboratory to ACS for 28.7 million euros of EU funds. It will investigate contagious viruses between humans and animals (https://www.vozpopuli.com/economia_y_finanzas/gobierno-adjudica-laboratorio-contra-pandemias-acs-28-millones-fondos-ue.html#:~:text=En%20su%20search%20of%20the,among%20humans%20and%20animals%2C%20as)
Companies
- International News
- The president of Novartis says that the US price reform represents a threat to Public Health (https://www.ft.com/content/46584130-85df-4e63-b197-3ea26bab6809)
- GSK raises its forecasts after strong sales in vaccines and HIV therapy (https://www.ft.com/content/bf5a1acd-c44c-465a-ac04-59ffda16ccf9)
- AstraZeneca ahead of forecasts, given strong sales of cancer and diabetes therapies (https://www.ft.com/content/430604de-be9a-4296-a8d9-aaa5702ed1b3)
- Pfizer registers a collapse of more than 30% on the stock market, given the drop in demand for covid vaccines (https://www.consalud.es/salud35/bolsa/pfizer-registra-desplome-bolsa-caida-demanda-vacunas-covid_132799_102.html#)
- Bayer cuts its forecasts for 2023 and estimates a loss of 2 billion euros (https://cincodias.elpais.com/companias/2023-07-24/bayer-recorta-su-perspectiva-para-2023-y-preve-a-2000-million-loss.html#)
- Abbott reduces its profit by 39.7% in the first semester (https://www.plantadoce.com/empresa/abbot-reduce-un-397-su-beneficio-en-el-primer-semestre.html)
- Biogen, the most promising company against Alzheimer’s, launches a takeover bid of 7.3 billion after laying off 1,000 employees (https://cincodias.elpais.com/companias/2023-07-28/biogen-la-empresa-mas-prometedora-against-alzheimer’s-launches-a-7.300-million-takeover-bid-after-firing-1000-employees.html)
- National News
- Health spending on biosimilars breaks records, exceeding 1 billion (https://www.eleconomista.es/salud/noticias/12381114/07/23/el-gasto-sanitario-en-biosimilares-bate-record-al-exceed-1000-million.html)
- Sanitas will grow in Palma with a new multi-specialty center (https://www.plantadoce.com/empresa/sanitas-crecera-en-palma-con-un-nuevo-centro-multiesespecialidad.html)
- Grifols loses 56.2 million euros in the first half due to restructuring costs (https://cincodias.elpais.com/companias/2023-07-27/grifols-pierde-56-millones-de-enero-a-June-due-to-restructuring-costs-and-raises-sales-by-15.html)
- Almirall cuts profit by 56%, but increases its sales by 7% and maintains forecasts (https://cincodias.elpais.com/companias/2023-07-24/almirall-recorta-el-beneficio-un-56-until-june-but-it-raises-its-sales-by-7-and-maintains-forecasts.html)
- Dental Residency finalizes its landing in the United Kingdom (https://www.plantadoce.com/company/dental-residency-last-his-disembarkation-in-united-kingdom.html#:~:text=The%20company%20is%20in%20process,continues%20with%20his%20international%20adventure.)