Posts

7 days in healthcare (15th-21st, 2024)

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Summary

From the point of view of Biomedicine, after an extensive study it is detected that in approximately 1 in 10 cases of multiple sclerosis, antibodies are detected in the blood years before the disease develops. It may be too early to draw conclusions about the repercussions of this finding.

As far as Global Health is concerned, plans to expand vaccine production to Africa are facing serious problems. This follows Moderna’s halt to the construction of a €500 million plant in Kenya, although other schemes continue, such as plans including facilities in Rwanda, Senegal and South Africa, carried out by BioNTech. Producing more vaccines in Africa is a moral imperative, says Martin Friede, head of vaccine research at the WHO. Article in Lancet Americas: Corruption, the greatest threat to healthcare. The cases in Peru as a result of the covid-19 pandemic and in Brazil (Rio de Janeiro) are discussed. It seems to be demonstrated, analyzing the experience of the few countries in which cannabis consumption has been legalized for a few years, that its legalization produces an increase in consumption in adults.

In terms of International Health Policy, initiatives in the USA against Chinese biotech companies will harm American patients. The Biosecure Act, which gained bipartisan support in Congress, proposes ending government contracts with biotechnology firms that have agreements with Chinese companies as clients or suppliers. This can greatly harm Americans, since, for example, BGI (Beijing Genomics Institute) is the largest human DNA sequencer in the world and operates in 100 countries. Facilitates the manufacture of prenatal tests and other diagnostic tests. In the United Kingdom, Brexit has exacerbated drug shortages in pharmacies. This is deduced from the study by the Nuffield Trust, a prestigious British health think tank, which released a report analyzing the impact of Brexit on the health system. Also in the United Kingdom there is a report published by Reform, a British think tank committed to public services and the effectiveness of the State, proposing a major organizational change in the health system in England, trying to decentralize and abolishing NHS England, since it is considered that such a centralized system is preventing the transition towards a more preventive model, guided by local needs. The role of NHS England would be assumed by the Department of Health, although with a much more strategic vision. England (with around 57 million people) is considered to be the most centralized healthcare system in Europe, despite devolution processes in Scotland (5.4 million), Wales (3.1 million) and Northern Ireland (1.9 million). This same idea of the problems of large centralization of the NHS is held by Nigel Edwards, former chief executive of the Nuffield Trust and now senior associate. The House of Commons votes in favor of the ban on smoking for those born after 2009, despite the Prime Minister being met with the vote against more than 50 Conservative MPs. A controversial measure whose only precedent is New Zealand and was recently repealed by the new government. In Germany, a commission recommends that abortions be legalized in the first 12 weeks. Although abortions in Germany are regulated by a 153-year-old law and are illegal, in practice they are performed in an accessible way. It is assumed that the current law does not meet current international standards.

If we talk about National Health Policy (Spain), the Ministry of Health seems to focus on issues such as the promise to the white tides of the imminent hearing of the Public Management Law; while the Commissioner of Mental Health prepares a guide to reduce psychotropic drugs, as well as launching more than debatable messages such as that “long-term drug treatments kill. These people live 20 years less”, which generated a negative response from Dr. Celso Arango, from the Gregorio Marañón Hospital; or he tries to change the 24-hour guard system, without really knowing how; “green” anesthesia; announcements that possibly, as intended in the United Kingdom, smoking will be banned for those born after 2009; etc. It does not seem that a very varied set of measures on often non-central issues constitute a strategy of anything. While serious underlying problems remain or worsen, such as waiting lists, which in the Ministry’s last publication reached a record of more than 850,000 people waiting. The Zendal Hospital, of the Community of Madrid, admitted one patient a day in 2023. It is increasingly clear that this hospital, launched without a minimum professional planning project, is a clear example of bad governance. The WHO threatens to break its agreement with the Andalusian School of Public Health, if it is diluted in the new Health Institute. The entity warns that the bilateral agreement signed in 1989 is not “transferable” and that, unless it is negotiated again, the collaboration as an associated center “automatically comes to an end.” The plans of the Andalusian Government in relation to the prestigious Andalusian School of Public Health are difficult to understand. Possibly the most regrettable operation underway in public health in Spain at the moment are the famous OPEs. The temporality wants to be resolved with a system of coverage of places with regional calls, not participating in the selection of the professionals nor the hospitals nor, much less, the services involved. There is a risk of destroying the unit and the configuration of services, which in many cases took years to implement. A real shame, much to the taste of the more traditional administration and the unions. In this sense, the 76 service heads of the 12 de Octubre hospital, in Madrid, have sent a letter to the counselor, warning of the problem of disintegration of services as a consequence of the ongoing OPE. We must see, in this sense, the recommendations of the Commission for Social and Economic Reconstruction, in whose opinion approved in Congress, it is committed to a national qualification for medical specialists and local hiring. In the MIR call, the worst figure is for Family Medicine, with 459 free places in the first round, double that in 2023. Making family medicine attractive – salary-wise and professionally – is indeed an emergency to be addressed and a problem important. The newspaper El Mundo reports on the cheapest health insurance. From ASISA (25.99 euros/month) to Sanitas (51.68). In all of them, hospitalization is included, with some form of co-payment. If this isn’t a price war, it certainly looks a lot like one. It is not surprising then that there are problems with rates for hospitals and professionals.

As for Companies, internationally, funds are moving on the board of Novavax, after the failures in the covid vaccine. In terms of national information, AI will revolutionize mental health, generating 2.5 billion euros in Spain. The largest seller of flu vaccines in Spain entrusts its production to Rovi.

Biomedicine

Global Health

International health policy

  • USA
    • Philip Morris funds smoking cessation plans. Medscape, a leading health information company in the USA, is accused of having accepted courses financed by this company. The criticism is based on the tobacco industry’s history of ignoring scientific teachings about the dangers of tobacco (https://www.bmj.com/content/385/bmj.q830)
    • American movements against Chinese biotech companies will harm American patients. The Biosecure Act, which gained bipartisan support in Congress, proposes ending government contracts with biotechnology firms that have agreements with Chinese companies as clients or suppliers. This can greatly harm Americans, since, for example, BGI (Beijing Genomics Institute) is the largest human DNA sequencer in the world and operates in 100 countries. Facilitates the manufacture of prenatal tests and other diagnostic tests (https://www.economist.com/leaders/2024/04/18/americas-moves-against-chinese-biotech-will-hurt-patients-at-home)
    • Scientists miss action against bird flu outbreaks on American farms (https://www.nytimes.com/2024/04/19/health/bird-flu-usda-cattle.html)

National health policy

  • Central government initiatives
    • Sánchez announces the expansion of the basic screening portfolio from 7 to 11 detectable diseases (https://www.diariomedico.com/medicina/politica/sanchez-anuncia-ampliacion-cartera-basica-cribado-neonatal-7-11- detectable-diseases.html)
    • García announces to the white tides the imminent hearing of the Public Management Law (https://diariofarma.com/2024/04/11/garcia-anuncia-a-las-mareas-blancas-la-inminente-audiencia- of-the-public-management-law-of-the-sns)
    • The Commissioner of Mental Health prepares a guide to reduce psychotropic drugs, as well as launches more than debatable messages such as that “long-term pharmacological treatments kill. These people live 20 years less”, which generated a negative response from Celso Arango , from the Gregorio Marañón Hospital (https://www.diariomedico.com/medicina/politica/comisionado-salud-mental-prepara-guia-prescripcion-psicofarmacos-reducer-consumo.html)

Companies

7 days in healthcare (February 12th-18th, 2024)

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Summary

From the point of view of Biomedicine, as is known, most rare diseases have no treatment, although this situation will surely be overcome in the not too distant future. A new drug (prozelimab) against the rare Chaple disease. A trial offers hope that a jab could prevent rheumatoid arthritis, the disease that affects 18 million people globally. Chances of a blood protein test warning about the onset of Alzheimer’s disease up to fifteen years in advance. A new powerful antibiotic (cresomycin), hope for antimicrobial resistance, which globally causes about five million deaths a year.

Regarding Global Health, despite the fact that 2021 marked the 100th anniversary of the appearance of insulin, many diabetes patients still do not have access to it. Important article in the New England Journal Medicine about e-cigarettes. There is sufficient evidence to show that switching from cigarettes to e-cigarettes reduces exposure to tobacco toxins, decreases respiratory symptoms, and reverses physiological changes related to cigarette smoking. There is not enough evidence that e-cigarettes are a good method to quit smoking.

In terms of International Health Policy, an unexpected consequence of the ruling of the United States Supreme Court, granting states the possibility of legislating on abortion, what was widely used to prohibit or restrict it: the taking of prescribed abortion pills by telemedicine and received by mail is a safe and effective method, according to a study. The European Commission approves the first gene editing treatment, in this case for beta thalassemia and sickle cell anemia. HERA (Health Emergency Preparedness and Response Authority) launches the Critical Medicines Alliance. It is said that this Alliance will contribute to changing the way medicines are produced and purchased in Europe.

If we talk about National Health Policy (Spain), there is great commotion in the sector as a result of the statements by Vice President Yolanda Díaz that she is negotiating to introduce in the budgets the modification of the health VAT from 0% to 21%. Regardless of the viability of this proposal, could it be considered whether this is the best way to make policy? Any study on the impact on the sector? Any previous negotiations with the health ecosystem? Although the Ministry of Health usually intervenes little in economic matters – remember that all the cuts during the financial crisis were not even discussed in the Interterritorial Council of the National Health System – this is a major issue that well deserves a position. and an analysis by the Ministry of Health. Asturias regulates financial compensation to professionals (442 euros for four hours of surgical activity and half for consultations for doctors) for extension of working hours to address the serious problem of waiting lists. Family doctors report a deficit of 2,600 professionals in the next year. As a consequence of the European Plan against Cancer, the launch of the first nine Comprehensive Cancer Centers in Spain is announced. The project is led in Spain by the Vall d’Hebron Hospital and the National Institute of Oncology.

As for Companies, on an international level, the British consulting firm Clarivate analyzes the 13 disruptive drugs for 2024. Oncology drugs predominate, although there is also the vaccine against respiratory syncytial virus and a new drug against COPD. At the national level, the growth of the egg freezing business in Spain is confirmed. It seems that the HIPRA vaccine is going to end up in the trash. There is nothing special, since failures are inherent to business, especially in an area as difficult as biotechnology. However, some excessively triumphalist government demonstrations could have been avoided.

Biomedicine

Global Health

International health policy

  • United Kingdom and the National Health Service

National health policy

Companies

7 days in healthcare (June 26th-July 2nd, 2023)

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Summary

From the point of view of Biomedicine, clinical trials in humans begin with drugs developed by artificial intelligence, such as one for idiopathic pulmonary fibrosis. Álvaro Pascual-Leone, a prestigious Spanish neuroscientist based in the United States, announces that in about ten years the brain will be able to be manipulated . Surely at that time the manipulation of the brain will be something as normal as today the replacement of the crystalline lens for the cataract. A new world is coming.

In Global Health, two charities (the Gates Foundation and the Wellcome Foundation) set to fund a TB vaccine, which could save 8.5 million lives over the next quarter century. Gavi, the organization that provides vaccines to developing countries, approves a vaccine that protects against polio and five other diseases.

Regarding International Health Policy, the editor of the American Journal Medicine publishes in the last issue an article with the five great challenges of the American health system in the 21st century. However, from a reporting point of view, the most interesting news comes from the UK. The King’s Fund, a major British health think tank, publishes a comparative analysis of that country’s health system, which it analyzes together with 19 health systems, including the Spanish one. The analysis is very interesting, and the conclusion is that the NHS is efficient, but with big problems, not only with waiting lists, but also with results. It seems to imply a chronic underfunding of the NHS, when compared to systems in other countries. For its part, the NHS publishes for the first time a long-term plan on personnel. It basically deals with three things: training, retention and reform. The Guardian hails the report but says it is years overdue. For their part, both The Lancet and the British Medical Journal publish editorials on the 75th anniversary of the NHS, which coincides with its deep crisis. In both positions, political consensus is claimed as a key piece to fix the serious problems of the NHS. The WHO-Europe publishes a document with architectural recommendations on the hospitals of the future.

If we talk about National Health Policy (Spain), there are several news of interest: the Audit Office of Catalonia publishes an interesting report on waiting lists. It seems that 9% of the cases on the waiting list in Catalonia were not counted on the Department of Health website, which leads some to use the word makeup. With regard to private healthcare, the IDIS is starting a very interesting project to share the patient’s clinical history among various provider and insurer entities, only an initial but very important step in what is to come. In the course of the pre-election debate, the President of the Popular Party announces a new General Health Law and a State Pact on Health if it reaches La Moncloa. Interesting announcements since, as The Lancet says for the NHS, only a certain political consensus and a new partnership, will be able to solve the problems of the health system in our country.

At the Corporate level, internationally, GSK completes the acquisition of Bellus Health. As far as national news is concerned, we must highlight Roche’s investment in Sant Cugat.

Biomedicine

Global Health

International Health Policy

  • USA
    • The challenges of the American healthcare system in the 21st century, according to the editor of the American Journal Medicine. Five big challenges: 1. Insufficient insurance coverage; 2. Low health education among the population; 3. Prevention and management of chronic diseases; 4. Great disparities in quality and results; and. 5. Trust in doctors? (https://www.amjmed.com/article/S0002-9343(23)00035-9/fulltext)

National Health Policy

Companies

 

 

 

 

 

7 days in healthcare (November 21st-27th, 2022)

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Summary

Most notably from the Biomedicine standpoint, the FDA is approving a drug that could delay the onset of type 1 diabetes, the devastating disease that often occurs in adolescents. Also the preclinical study that seems to foreshadow a universal flu vaccine. Likewise, the minirobot designed by Apple capable of taking medicines to the brain, that organ until now practically inaccessible to drugs.

With regard to Global Health, the COP27 summit is considered in an article in The Lancet a “collective failure”, given the lack of agreement on the lower use of fossil fuels. We must also note the race for the production of vaccines in several African countries.

Regarding International Health Policy, mortality from covid remains high and is very worrying in some countries, mainly Japan, Brazil, India, China, the Russian Federation, South Korea and Spain. The covid-zero policy is generating problems and discontent in a country where public demonstrations are as controlled as in China. The nurses’ strike in the United Kingdom is a historic event in that country, which will undoubtedly will have consequences.

If we talk about National Health Policy (Spain), mortality from covid remains high in Spain (260 cases in the last week). At this time Spain has 0.6 deaths per 100,000 inhabitants, a fairly high mortality, although lower than other European countries, such as France, Greece, Denmark, Norway, Croatia, Estonia and Luxembourg, according to WHO data. The waiting lists for June 30 are published by the Ministry of Health. A real national problem and a serious delegitimization of the public system, which some minimize. The strike of Primary Care doctors continues in Madrid, while the conflict threatens to spread to other autonomous communities. The rise in the electricity bill threatens the profitability of private hospitals, according to ASPE.

In the field of Companies, at the international level, Amazon is making a new foray into healthcare, this time with the “Amazon Clinic” platform, a telemedicine service that will be extended to 32 American states and offers virtual care for 20 clinical conditions. At the national level, news at HM Hospitales, with the new hospital in Rivas; in Recoletas, which extends to Salamanca; and, in Sanitas, which intends to create its own clinical analysis laboratory.

Biomedicine

Global Health

International Health Policy

National health policy

Companies

  • International News
    • Amazon makes a new attempt at healthcare. The offers of the big technological platforms are diversified: Apple tries to monitor through the iPhone; Microsoft, offers computer services to companies; Alphabet (Google), relies on wearables. Amazon launches the most ambitious offer, with “Amazon Clinic”, an online service that will operate in 32 American states and that offers virtual care for 20 clinical conditions, from acne to allergies (https://www.economist.com/ business/2022/11/20/amazon-makes-a-new-push-into-health-care)
    • The big pharma aims for 50,000 million dollars in medicines against obesity, a disease that affects 650 million people in the world, as demand grows. Lilly will submit a drug for authorization (https://www.ft.com/content/f28e8ca1-87a7-4c14-8b05-0ead0e831c0f)

 

 

7 days in healthcare (September 26th-October 2nd, 2022)

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Summary

From the point of view of Biomedicine, to review the advances, still to be confirmed, in the treatment of two terrible diseases: ALS and Alzheimer’s.

Regarding Global Health, concerns continue about the evolution of polio, whose eradication was announced in 2019, but which is reappearing in several countries.

Regarding International health policy, it is worth noting the similarities between the covid-zero policy in China and the era of prohibition in the United States, something pointed out by The Economist. Very worrying is the “burnout” of doctors, a phenomenon highlighted by the New York Times in the United States, but which seems to be universal.

If we talk about National health policy (Spain), the debates on the Equity Law continue. The update of the RD on the minimum data set of the SNS leaves out the private sector, despite the opposition of the POP, IMAS Foundation, IDIS Foundation and ASPE. It is a modification of a 2010 RD, but in twelve years the private sector has developed a lot and it is no longer so easy to leave it out in certain decisions. The Senate rejects the PP’s motion to facilitate access to medicines and reduce the time it takes to join the SNS. Surely the motion of the PP was too vague and, at this point, it is necessary to explain very well the “what” and the “how” of any proposal.

At the corporate level, at the international level, big rise in Biogen shares, spurred by what appear to be hopeful results from its Alzheimer’s drug. At the national level, there are rumors that KKR and CVC could be trying to buy Quirónsalud, currently in the hands of the German group Fresenius, which has recently changed its CEO. The Murcian company Vócali develops the Inbox Medical software for transcription of medical reports.

Biomedicine

Global Health

International health policy

National health policy

Companies

 

7 days in healthcare (September 12th-18th, 2022)

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Summary

From the point of view of biomedicine, immunotherapy (in colon cancer) and CAR-T therapies (in lupus) continue to expand their therapeutic possibilities. Advances against infections for resistant bacteria. Will there ever come a time when cancer can be diagnosed by a simple blood test? This possibility does not seem very remote, according to papers presented at the meeting of the European Society of Medical Oncology.

Regarding Global Health, an important work directed by Jeffrey Sachs and published by The Lancet on the delays and errors of both governments and the WHO in dealing with the covid pandemic, which could have produced 17.7 million of  deaths, many of them preventable.

Regarding international health policy, the WHO says that the end of the covid pandemic may be in sight, although at the same time a new variant (BJ.1) of covid is evident in Europe. Important debate in Europe (Scotland and France) on euthanasia and assisted death. The French Ethics Committee opens the door to this possibility. The financing of the American FDA was questioned, due to its great economic dependence on the pharmaceutical industry. Biden launches a speech commemorating Kennedy’s in 1962 when he decided to go to the Moon, but this time oriented towards the fight against cancer.

If we talk about national health policy (Spain), the PDeCAT presents an amendment to the entire equity law, which it accuses of interfering in regional powers and of confusing agreement with privatization. Surprising statements from the Ministry of Health in a parliamentary response, saying that its functions in relation to the waiting lists are only to inform and monitor, as if it did not have the possibility of signing agreements with the communities to address this problem or of launching other actions. Concern, there are even demonstrations in the street, of the relatives of the elderly admitted to residences. The Community of Madrid announces that it will reduce the waiting lists by half. Although we would like it not to be the case this time, this announcement is preceded by other similar ones from different governments, which always came to nothing in terms of effectiveness. The search for solutions by the Ministry of Finance to the MUFACE model, highly impacted by inflation, seems to recognize its underfinancing.

In the field of companies, from the international point of view, important success for Sanofi, with its new vaccine against bronchiolitis. In Spain, important corporate movements in Korian, HM Hospitales, Miranza and Ribera.

Biomedicine

Global Health

International health policy

National health policy

Companies

 

7 days in healthcare (30th May-5th June, 2022)

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Summary

From the point of view of biomedicine, to highlight the Science article, showing that the brain and the immune system are interconnected. Monkeypox is transmitted by direct contact, therefore “ring vaccination” is indicated, only to contacts of an infected person.

As far as Global Health is concerned, the universal coverage approach in Nigeria, the most populous country in Africa, should be highlighted. It is seen that universal coverage is no longer just something of Europe or the industrialized countries.

As for international health policy, the frequent shootings in American schools are covered by medical journals (The Lancet, British Medical Journal), as it is also a health problem. Something perfectly avoidable.

If we talk about national health policy (Spain), it should be mentioned that private health offers to collaborate with public health in addressing the problem of waiting lists.

In the field of companies, Takeda’s statements are surprising, saying that pharmaceutical companies will be able to lower prices in the face of a global crisis. The acquisition of the HIPRA vaccine by Brussels is advancing.

Biomedicine

Global health

International health policy

  • Monkeypox

o 21 Americans affected by monkeypox, according to the CDC (https://www.nytimes.com/2022/06/03/health/monkeypox-vaccine-treatments.html)

o New York Times editorial: To fight monkeypox we have to learn the lessons of covid and HIV (https://www.nytimes.com/2022/05/29/opinion/monkeypox-covid-and- hiv.html)

o Concern in Europe that massive summer parties spread monkeypox (https://www.lavanguardia.com/vida/20220605/8317253/pretrabajo-fiestas-masivas-verano-extend-viruela-mono.html)

  • COVID-19

o Covid cases on the rise in the Americas: North and Central America) (https://www.bmj.com/content/377/bmj.o1355)

o Does the world need new covid vaccines? (https://www.nejm.org/doi/full/10.1056/NEJMe2204695)

o Doubts about whether the arrival BA.4 and BA.5 of the omicron will mean a new wave of covid in France (https://www.lemonde.fr/planete/article/2022/06/04/covid-19 -l-arrivee-de-ba-4-et-ba-5-en-france-va-t-elle-entrainer-une-nouvelle-vague-de-contaminations_6128892_3244.html)

o The subvariant of the BA.5 omicron is a cause of concern in Portugal (https://www.lemonde.fr/planete/article/2022/06/04/au-portugal-le-sous-variant-ba-5-d-omicron -restless_6128944_3244.html)

o The zero-covid policy in China is unfeasible in the long run, the only question is when it will abandon it to “live with covid”. Article in Science magazine (https://www.science.org/doi/10.1126/science.add1891)

  • Other themes

o The frequent shootings in American schools, also as a health problem, treated in medical journals. The Lancet: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)01006-6/fulltext; British Medical Journal: https://www.bmj.com/content/377/bmj.o1378

o The black market of antivirals for covid (https://www.bmj.com/content/377/bmj.o1282)

o Shortage of doctors in Italy (https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)01009-1/fulltext)

o Medical abortion and telemedicine in a post-Roe v Wade phase (https://www.bmj.com/content/377/bmj.o1393)

o The Center for Medicare and Medicaid (CMS) in the USA plans to advance Value Based Healthcare (https://jamanetwork.com/journals/jama/fullarticle/2792275)

National health policy

  • Monkeypox

o Spain reaches 132 positives for monkeypox (https://www.consalud.es/pacientes/infecciosas/viruela-mono-espana-casos_115507_102.html)

  • COVID

o The incidence of covid in people over 60 years of age falls 45 points again (https://www.abc.es/sociedad/abci-incidencia-covid-mayores-60-anos-volve-caer-45-puntos-202206031649_noticia .html)

  • Regulatory announcements

o The Order to allocate 217 places to non-EU citizens was published in the Official Bulletin (BOE) (https://www.consalud.es/especial-mir/boe-orden-adjudicar-217-plazas-mir-vacantes-extracomunitarios_115651_102.html)

  • Other themes

o Private healthcare offers to reduce surgical waiting lists by 30%, according to ASPE (https://www.eleconomista.es/salud/noticias/11799678/06/22/La-sanidad-privada- offered-to-reduce-the-surgical-waiting-list-by-30.html)

o Aragon extends dental care up to 14 years of age (https://www.consalud.es/autonomias/aragon/aragon-amplia-hasta-14-anos-programa-atencion-salud-bucodental_115455_102.html)

Companies

  • International News

o GSK is going to buy the Affinivax biotech group for 3.0 billion dollars (https://www.ft.com/content/3a5e33ea-1af6-4554-bf50-225441fe4c24)

o BMS about to acquire drugmaker Turning Point for $4.1 billion (https://www.ft.com/content/9c5b319c-20c3-4558-826f-260d0698975b)

o Takeda says that pharmaceutical companies could lower prices in the face of a global crisis (https://www.ft.com/content/492beff8-a077-421e-8da9-faf378e15175)

o The company that manufactures the monkeypox vaccine has the capacity to produce 30 million doses (https://www.elespanol.com/invertia/observatorios/sanidad/20220531/empresa-fabrica-vacuna-viruela-capacity-produce -millions/676432695_0.html)

  • National News

o Brussels finalizes the acquisition of the HIPRA vaccine for covid (https://www.eleconomista.es/salud/noticias/11791545/05/22/Bruselas-ultima-la-adquisicion-de-la-vacuna-espanola-de -Hipra-for-the-Covid.html)

o HM acquires the Los Nogales Pontones center to build a new hospital (https://www.plantadoce.com/empresa/hm-hospitales-acquire-el-centro-los-nogales-pontones-para-levantar-un-nuevo- hospital.html)

o Vithas recovers from the covid downturn and grows 19% in 2021 (https://www.plantadoce.com/empresa/vithas-se-recupera-del-bache-del-covid-19-y-crece-un -Jan-19-2021.html)

o Grupo HLA targets 500 million revenues in 2022 (https://www.plantadoce.com/empresa/grupo-hla-apunta-a-500-millones-de-euros-en-ingresos-en-2022.html)

o The contracting of medical insurance skyrockets in Cantabria and Catalonia in 2021. At the national level, 24% of the population has private medical insurance, although low cost ones are included (only consultations and tests) (https://www. .elespanol.com/invertia/observatorios/sanidad/20220605/contratacion-seguros-medicos-dispara-cantabria-cataluna/677432488_0.html)

o The laboratories devastate the funds in their bid for Lacer (https://www.expansion.com/empresas/2022/05/30/6293eb1ee5fdea29048b45f4.html)

o Vithas has an agenda to achieve the 2030 goals (https://www.redaccionmedica.com/secciones/privada/vithas-se-fija-2025-para-alcanzar-el-80-de-los-objetivos-de-la -phonebook-2030-9828)

o DKV presents the 2021 corporate report and the Imagina 2025 Strategic Plan (https://dkv.es/corporativo/sala-prensa/noticias/informe-anual-2021)

7 days in healthcare (May 9th-15th, 2022)

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Summary

From the point of view of biomedicine, the important study published by the journal Science should be highlighted, outlining the most detailed atlas of human cells to date. The discussion about the origin of acute childhood hepatitis continues.

As far as Global Health is concerned, it is found that the United States has reached one million deaths from COVID and Europe two million. A sad milestone.

Regarding international health policy, in relation to COVID, the debate continues on the sustainability of the zero-COVID policy in China. Lockdowns in North Korea, possibly the most opaque country in the world. The debate continues in the United States on the modification of the Roe v Wade sentence. Pronouncements from scientific journals (Nature, The Lancet), as well as from the President of the American Medical Association. The ECDC (European Center for Disease Prevention and Control) stops recommending the use of masks on public transport in Europe.

If we talk about national health policy (Spain), the accumulated incidence of COVID continues to grow. Great debate regarding the announced new Abortion Law. It is more than doubtful that the Law will be approved and, if it is, that it will be complied with, given the large number of controversial elements (registration of conscientious objectors, the obligation that these interventions be carried out in public hospitals, the use of terminology of obstetric violence, etc.). The Ministry of Industry takes out the first tender of the cutting-edge health PERTE. Important editorial in El País on waiting lists, which it presents as a scourge of the SNS.

In the field of companies, the WHO denounces attempts to whiten tobacco companies, by way of presenting themselves as green companies.

Biomedicine

Global Health

International health policy

  • COVID-19

o The Director of the WHO affirms that the zero-covid policy in China is not sustainable (https://www.ft.com/content/9b81b9f0-e13d-4b0a-8bdf-91c97c7d61e7)

o A study says that lifting the “zero COVID” policy in China could mean 1.5 million deaths (https://www.theguardian.com/world/2022/may/11/lifting-zero-covid-policies-in -china-could-risk-16m-deaths-says-study)

o China considers the WHO statement on its zero COVID policy “irresponsible” (https://www.ft.com/content/2e20867b-5f1d-4307-93b0-1d9b07d65e34)

o China renounces organizing the 2023 Asian Soccer Cup, due to the pandemic (https://www.lemonde.fr/international/article/2022/05/14/la-chine-renonce-a-organiser-la- coupe-d-asie-2023-de-football-in-raison-de-la-pandemie-de-covid-19_6126096_3210.html)

o Confinement in North Korea, as the first cases of COVID are confirmed (https://www.ft.com/content/41dec58c-3860-4ae3-86c4-716ffe85dbdd)

o Alert in the state of New York, due to the increase in cases (https://www.nytimes.com/live/2022/05/13/world/covid-19-mandates-vaccine-cases)

  • The debate on abortion continues in the United States

o The pronouncement of medical and scientific journals continues against the annulment of the Roe v Wade ruling in the United States, for reasons of public health and worsening of the health of women and children, particularly those with fewer resources. Editorials in Nature (https://www.nature.com/articles/d41586-022-01249-2) and The Lancet (https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22) 00870-4/fulltext), among others.

o Gerald E. Harmon, President of the AMA, the representation of American doctors, was “deeply concerned” about the impact on reproductive health in the United States of this possible modification (https://www.ama-assn.org/ delivering-care/population-care/why-leaked-abortion-opinion-antithetical-public-health)

o The New York Times assures that the annulment of same-sex marriage could be the next step (https://www.nytimes.com/2022/05/11/us/politics/roe-wade-supreme-court- abortion.html)

o Certain groups try to ban telemedicine prescription of pills that interrupt pregnancy (https://www.ft.com/content/6a3dd70e-8bb9-4727-af4a-4036a660db64)

  • Other themes

o The United States, willing to share vaccine technology with poor countries, says Biden (https://www.ft.com/content/ec6b5b3a-7cff-4aa9-8e68-cba3bbaae06f)

o The European Union Aviation Safety Agency and the European Center for Disease Prevention and Control (ECDC), eliminate the recommendation to use masks in airports and during flights (https://www.larazon.es/ society/20220511/2dur4ogv7zemfkl5bbwmsitpme.html)

o Disposable electronic cigarettes are imposed among adolescents in France (https://www.lemonde.fr/societe/article/2022/05/08/les-cigarettes-electroniques-jetables-s-imposent-parmi-les-adolescents_6125199_3224 .html)

o France will stop requiring a mask on public transport starting next Monday, May 16 (https://www.expansion.com/economia/2022/05/12/627ccd8e468aeb71118b4611.html)

National health policy

  • COVID

o The accumulated incidence continues to rise, growing 13 points since the last measurement and standing at 856.65 cases in the last 14 days per 100,000 inhabitants. The ward occupancy rate is 5.80% and the ICU occupancy rate is 4.07% (https://www.consalud.es/pacientes/especial-coronavirus/covid-19-espana-suma-31036-casos- 321-deceased-ia-uploads-856-points_114645_102.html)

  • Regulatory announcements

o The Government willing to approve next Tuesday, May 17, a new abortion law at the initiative of the Ministry of Equality. The 14-week period for abortion to be considered legal is not modified. Most controversial points: 1. Without permission or information to parents from the age of 16; 2. No to surrogacy; 3. Registration of conscientious objectors; 4. Abortion in public hospitals; 5. Leave due to painful menstruation, outside the regulations of the common disease; 6. The terminology of obstetric violence is maintained (https://www.abc.es/sociedad/abci-no-reforma-sino-ley-aborto-ultima-gobierno-diez-claves-rapidas-202205111920_noticia.html)

o The need to strengthen public healthcare so that it can address the 74,000 abortions that are performed in the private sector (https://elpais.com/sociedad/2022-05-14/la-sanidad-publica-debera-reforzarse-para-asumir -the-74000-abortions-that-now-derives-to-the-private.html)

o The Constitutional Court is preparing a ruling in favor of the 2010 Abortion Law for June, after an appeal by the PP, parked for 12 years (https://www.elconfidencial.com/espana/2022-05-13/constitucional-junio -judgment-favorable-law-abortion_3423623/)

  • Other themes

o The Ministry of Industry is putting out to tender the Vanguard Health PERTE for the pharmaceutical and health products sector (https://www.boe.es/boe/dias/2022/05/07/pdfs/BOE-B-2022-14280 .pdf)

o Important editorial in El País on waiting lists, which it presents as a major problem for the SNS (https://elpais.com/opinion/2022-05-10/largas-listas-de-espera.html)

o War of figures in the strike of medical specialists in Madrid (https://elpais.com/espana/madrid/2022-05-10/primer-dia-de-huelga-indefinida-de-medicos-en-madrid-basta -already-of-temporary.html)

o Castilla y León intends to lower the surgical delay in six months by 21 days (https://www.diariofarma.com/2022/05/11/castilla-y-leon-objetivo-bajar-21-dias-la-demora -surgical-in-6-months)

o The national 024 telephone line for suicide prevention is launched (https://www.larazon.es/sociedad/20220509/cubyq6iicncg3nfm6hieltpxvy.html)

o The SNS Interterritorial Council gives the green light to the Mental Health Plan (https://www.diariofarma.com/2022/05/11/el-cisns-da-luz-verde-al-plan-de-salud-mental -con-practica-unanimidad), which is criticized by the President of the Spanish Society of Psychiatry, saying that “Mental Health needs professionals and intermediate centers, not apps” (https://www.redaccionmedica.com/secciones/psiquiatria /-mental-health-needs-professionals-and-intermediate-centers-no-apps–8807)

o The Ministry publishes the list of 462 strategic medicines, which includes 249 active ingredients (https://www.diariomedico.com/farmacia/industria/estos-son-los-462-medicamentos-estrategicos-para-el-sns. html)

o Private doctors ask insurers to raise their fees, which according to them have been frozen for 32 years (https://theobjective.com/economia/2022-05-15/medicos-privados-honorarios/)

o Andalusia can have up to 8 Faculties of Medicine, after the steps in Jaén and Almería only Huelva remains (https://www.redaccionmedica.com/bisturi/-ocho-facultades-de-medicina-en-una-misma-region –3332), something (the proliferation of Medical Faculties) totally against the approaches of the CEEM (State Confederation of Medical Students) and the Conference of Deans

Companies, employers and other agents of the sector

  • International News

o The WHO asks countries to stop the tobacco companies that try to whitewash their image as a green industry (https://elpais.com/clima-y-medio-ambiente/2022-05-13/la-oms-pide- to-the-countries-that-stop-the-tobacco- companies-that-try-to-clean-up-their-image-as-a-green-industry.html)

o Pfizer will buy the biotech company Biohaven for 11.6 billion dollars (https://www.ft.com/content/ea9bb9bc-b5ec-4278-ab42-1f5f14a1a76f)

  • National News

o Vithas invests 3 million euros in the renovation of emergencies (https://www.plantadoce.com/empresa/vithas-madrid-la-milagrosa-invierte-tres-millones-de-euros-en-la-renovacion- of-your-emergencies.html)

o Vitaldent is committed to dental aesthetics by incorporating 73 Smysecret spaces into its clinics (https://www.plantadoce.com/empresa/vitaldent-apuesta-por-la-estetica-dental-e-incorpora-73-espacios-smysecret-a -your-clinics.html)

o Asisa buys a 600m2 center in Zaragoza (https://www.ondacero.es/programas/en-buenas-manos/asisa-compra-centro-medico-600-zaragoza_20220510627a3bbc64c3c90001106b03.html)

o Hospitales Parque grows in Talavera with a new building for outpatient consultations (https://www.plantadoce.com/empresa/hospitales-parque-crece-en-talavera-de-la-reina-con-un-nuevo-edificio- for-external-queries.html)

o Sanitas, SegurCaixa Adeslas and Línea Directa, the most profitable insurers (https://www.expansion.com/empresas/banca/2022/05/09/627567d7e5fdea58068b45f4.html)

o Novartis will manufacture an oncology drug for the whole world in Barcelona (https://www.eleconomista.es/salud/noticias/11765483/05/22/Novartis-fabricara-en-Zaragoza-un-oncologico-para-todo-el -world-.html)

7 days in healthcare (1-7 november, 2021)

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ABSTRACT

From an international point of view, to highlight something we knew: that WHO, in its current configuration, is not prepared for global health challenges. However, this finding is important in the article in the British Medical Journal by Anthony Costello. Europe, once again in the center of expansion of the pandemic. The decision of the North American Democrats to reduce the price of medicines, via the negotiation in Medicare, is very far-reaching. This decision, if applied, will have major consequences for the entire pharmaceutical industry globally.

At the national level, to highlight the article in The Lancet, which says that Spain could have achieved group immunity. For the rest, the incidence of COVID continues to grow in our country, although it does not reach, by far, those of other European countries. Waiting lists are a big concern throughout Spain. Controversy over the new Equity, Universalization and Cohesion Law. Podemos wants to take advantage of it to repeal Law 15/1997, which allows the outsourcing of health services.

As a business activity, to highlight the two new antivirals against covid-19, one from Merck and the other from Pfizer. Merck has released the patent so that it can be used widely in developing countries. Novartis dissociates itself from Roche, selling it its 33% stake in the latter company.

INTERNATIONAL

  • The WHO, in its current configuration, is not ready for its purpose, but is limited by lack of funds and political interference, and this has been demonstrated in this pandemic that has produced more than 18 million deaths, writes the economist Anthony Costello in the British Medical Journal (BMJ, 3 Nov 21)
  • Europe once again at the center of the covid pandemic, says WHO, (The Guardian, 4 Nov 21)
  • The WHO warns of the increase in deaths from covid in 56 countries, and insists that vaccine manufacturers have not done their job well (ConSalud, 5 Nov 21)
  • Democrats in the United States reach an agreement to reduce the price of drugs, allowing the government to negotiate the price of Medicare drugs. The United States pays three times more for many drugs than Europe, according to a study by the Brookings Institution. Initially, the measure will be launched with the 12 most expensive drugs (FT, 2 Nov 21)
  • The fourth wave continues to beat the record of infections in Greece, with almost 7,000 daily (El Confidencial, 6 Nov 21)
  • Excess mortality grows in Russia, since the beginning of the pandemic (FT, 2 Nov 21)
  • The management of the pandemic leaves a trail of investigated political leaders: Brazil, France, Italy, Austria, India, … (El Debate, 2 Nov 21)
  • India’s successes against covid are analyzed: more than half of Indians have received at least one dose of the vaccine. 6 million are vaccinated every day (The Economist, 29 Oct 21)

NATIONAL

 

  • The Lancet suggests that Spain could have achieved group immunity. They are based on the high infections and the high percentage of vaccination (La Razón, 3 Nov 21)
  • The incidence of covid rises more than two points, to 53.7 cases per 100,000 inhabitants (El País, 5 Nov 21)
  • Madrid for the first time exceeds half a million patients to see the specialist. Experts warn that the pandemic has generated in Spain a dammed demand that will emerge in the coming semesters (El País, 5 Nov 21)
  • Spain, one of the five countries in which Covid-19 caused the greatest loss in life expectancy, according to a study published by the British Medical Journal (ABC, 3 Nov 21)
  • The Health Ministry sells a million vaccines to Australia, New Zealand and Paraguay, before they expire (El Español, 2 Nov 21)
  • The WHO requests to increase oral public coverage in Spain (Health Act. The proposal receives the support of the General Council of Dentists (Health Act, 5 Nov 21)
  • Podemos will not support the Darias Equity Law. The Ministry wants to promote a Law of Equity, Universality and Cohesion and Podemos does not support it by not repealing Law 15/1997, which allows the outsourcing of health services (ConSalud, 5 Nov 21)
  • The Health Ministry seeks location for its strategic reserve of covid material (El Periódico de España, 5 Nov 21)

COMPANIES, EMPLOYERS AND MAIN ACTORS IN HEALTH

 

  • Merck drug effective to treat covid-19. The drug is an oral antiviral, called molnupiravir, and has already been approved by the British Agency. It has been launched by Merck and Ridbback Biotherapeutics, a Florida-based biotech. The drug is indicated for the unvaccinated and for those vaccinated who develop the disease. The treatment will be worth US $ 700 in developed countries. Merck will allow the development of generics in 105 countries (The Economist, 4 Nov 21)
  • Alphabet, Google’s parent company, launches an AI company, Isomorphic Labs, for the discovery of new drugs. It will work together with DeepMinds, Google’s AI company (FT, 4 Nov 21)
  • Pfizer increases the sales forecast of its covid vaccine in 2021 to 36,000 million US $ (FT, 2 Nov 21)
  • Biogroup, a bioanalysis group piloted by Stéphane Eimer and with a presence in Belgium, Luxembourg and the United Kingdom, enters the Iberian Peninsula with the purchase of Cerba Internacional and Analiza (both owned by Marcelo Weisz). ASISA will retain its 50% stake in Analiza (Les Echos, 4 Nov 21)
  • Novavax, a protein-based American covid-19 vaccine, receives its first approval in Indonesia. May promote immunization in developing countries. An application for authorization has also been sent to Canada, the United Kingdom and the European Union (FT, 1 Nov 21)
  • Pfizer announces an antiviral pill (Paxlovid) that prevents 89% of hospitalizations and deaths from covid (El País, 5 Nov 21)
  • The Valencian government will propose to the Data Protection Agency a sanction to Ribera for withholding data from the Torrevieja hospital (eldiario.es, Nov 4 21)
  • Centene closes the year of the coronavirus with losses in its health adventure in Spain (Nov 6, 21)
  • “Son Espases”: the macro-investigation on the concession to OHL of this hospital in the Balearic Islands, which links the Balearic Islands with the illegal financing of the PP (eldiario.es, Nov 5, 21)
  • Novartis sells its 33% stake to Roche for more than US $ 20 billion. A relationship of more than twenty years between the two companies is ended (PlantaDoce, Nov 4, 21)
  • MD Anderson launches a clinical trials unit (PlantaDoce, 3 Nov 21)
  • Eugin expands through Canada and acquires the fertility centers of Trio Fertility (PlantaDoce, 2 Nov 21)
  • Affidea, a European provider of diagnostic imaging, outpatient services and cancer care, expands in Spain and Northern Ireland with two new acquisitions (PlantaDoce, Nov 3, 21)
  • The biotechnology company of Spanish origin Aura Biosciences, jumps to the Nasdaq (PlantaDoce, 3 Nov 21)
  • Rovi doubles its profit in the first nine months of 2021, to 99 million (PlantaDoce, 3 Nov 21)