7 days in healthcare (April 7th-13th, 2025)
Summary
The most impactful health news of the week were:
- Biomedicine: The Lancet proposes rethinking coronary artery disease to save lives, based not so much on symptoms but on atheroma.
- Global Health: Public health under Trump 2.0: in the short term, chaos; in the long term, a disaster for public health both domestically and internationally.
- International Health Policy: A dark moment for American science, with opportunities for Europe to attract scientists.
- National Health Policy. The Council of Ministers approves the draft Drug Law, which is rejected by the entire pharmaceutical sector and appears to contradict the announced Strategic Plan for the Pharmaceutical Industry.
- Business: Ribera reaches a five-year agreement with SERGAS for Povisa.
Biomedicine
- Rethinking coronary artery disease. Editorial in The Lancet. The change would consist of shifting from the clinical assessment of occlusion to atheroma. The change would involve monitoring individuals who may have arteriosclerosis, even without symptoms. According to a commission of 25 experts, this change in approach could save up to 8.7 million lives annually.
- NEJM Review: Generative AI in Medicine. This review analyzes the short-, medium-, and long-term opportunities for AI in medicine. In the short term: patient education and information synthesis; in the medium term, aids in medical diagnosis; in the long term, virtual health assistants, disease monitoring, and medical education.
Global Health
- Public Health Under Trump 2.0: An Unmitigated Disaster. According to an editorial in The Lancet Public Health, the short-term effects are confusion, uncertainty, and chaos; in the long term, a disaster for public health both domestically and internationally. This began with the withdrawal from the WHO and the Paris Climate Agreement; the freezing of millions of dollars for American national and international health programs; and the attacks on the CDC and the National Institute of Health (NIH), which threaten to undermine decades of progress and leadership. Secretary of Health Robert F. Kennedy Jr. is known for denying scientific evidence. His first 50 days have seen decisions that undermine science; they weaken the protection of vulnerable populations, risk increasing health inequalities, and threaten public health nationally and internationally. This is the meaning of the slogan “Make America Healthy Again.”
International Health Policy
- The pharmaceutical industry “obeys” Trump and begins investing in the US to avoid tariffs. This can be seen in companies such as the Swiss company Novartis, which has announced investments of $23 billion in the US, as well as J&J, which has announced investments worth €50 billion. This could have an impact on Europe, as Europe’s largest export to the US is medicine.
- A dark moment for American science. Right-wing populism contains a strong dose of skepticism toward science, at least in certain fields. This could impact public health and the economy, as the American scientific drive was at the foundation of its business development. In recent weeks, thousands of healthcare employees have been laid off, as well as those at the FDA, CDC, and the National Institutes of Health (NIH). This offers opportunities for other countries, primarily European, to attract American scientists.
- Starmer promises a centralized service for scientists to access data, with a public investment of 600 million pounds. The service will be hosted on the Wellcome Genome Campus in Cambridge.
- Concern and caution in the European Union regarding a possible pharmaceutical exodus to the United States.
National Health Policy (Spain)
- Government approves the new draft of the Drug Law. Main changes: prescription by active ingredient, with the possibility of changes in the drugs to be dispensed by pharmacists; changes in the prices of off-patent drugs, introducing the concept of “selected prices,” which can be changed every six months; limited prescribing possibilities for nurses and physical therapists. The entire pharmaceutical sector opposes the law: pharmaceutical professionals, pharmaceutical employers, and distributors alike. In principle, the principles of the law seem far removed from what was promised in the Strategic Plan for the Pharmaceutical Industry, so emphatically announced by the government after a couple of meetings between President Sánchez and the top global executives of the pharmaceutical industry. This plan, following Trump’s tariff policies and the provisions of this law, appears to have become a dead letter.
- Osakidetza’s offer to retain doctors: €56,629 salary and 28 days of vacation.
Companies
- International
- The former Novartis subsidiary threatens the revenue of one of Bayer’s best-selling drugs.
- National
- Significant success for Ribera. SERGAS and Povisa sign the new healthcare contract in Vigo for 195 million euros. The hospital will earn 17% more each year with the new agreement. This will serve an estimated population of 116,000 people.
Biomedicine
- Problems with AI drug development, according to an editorial in Science. The future of drug discovery may be AI, but the present is not yet. AI is in its infancy in this field. For AI to mature, developers need high-quality, non-proprietary databases to test and validate models, managed by independent organizations. Current AI models have proven effective in only a few areas due to the lack of standardized data (https://www.science.org/doi/10.1126/science.adx0339)
- NEJM Review: Generative AI in Medicine. This review analyzes the short-, medium-, and long-term opportunities for AI in medicine. In the short term: patient education and information synthesis; in the medium term, medical diagnostic aids; in the long term, virtual health assistants, disease monitoring, and medical education (https://www.nejm.org/doi/full/10.1056/NEJMsb2503956)
- Rethinking Coronary Artery Disease. Editorial in The Lancet. The shift would involve moving from the clinical assessment of occlusion to atheroma. The shift would involve following individuals who may have arteriosclerosis, even without symptoms. According to a commission of 25 experts, this change in approach could save up to 8.7 million lives annually (https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00497-0/fulltext)
- A simple 5-pound blood test can prevent thousands of heart attacks, according to a study. Researchers suggest that troponin testing can detect silent damage and predict the risk of future cardiovascular events. This could prevent thousands of heart attacks and strokes. This protein is found in the heart muscle and is released into the blood when the heart is damaged (https://www.theguardian.com/science/2025/apr/07/simple-blood-test-help-prevent-thousands-heart-attacks-study)
- Scientists recreate brain circuitry in the lab for the first time. This holds promise for new pain treatments (https://www.ft.com/content/f8d5404c-5a24-4e3a-9e0b-6987153cd41e)
- Gene therapy to slow Parkinson’s disease with an injection. The trial seeks to restore the function of dopamine-producing neurons. It has been in development for 36 months, and results are expected by the end of 2027 (https://www.larazon.es/salud/terapia-genica-frenar-parkinson-inyeccion_2025041167efbb5eeec2d30001456a7d.html)
- A new method allows Alzheimer’s disease to be detected with a blood test in people with symptoms. Detecting the disease with a simple blood test is getting closer, using the p-tau217 biomarker (https://elpais.com/ciencia/2025-04-09/un-nuevo-metodo-permite-detectar-el-alzheimer-con-un-analisis-de-sangre-a-personas-con-sintomas.html)
Global Health
- Public Health under Trump 2.0. According to an editorial in The Lancet Public Health, the short-term effects are confusion, uncertainty, and chaos; in the long term, a disaster for public health both domestically and internationally. It began with the withdrawal from the WHO and the Paris Climate Agreement; the freezing of millions for American national and international health programs; and the attacks on the CDC and the NHI, which threaten to undermine decades of progress and leadership. Secretary of Health Robert F. Kennedy Jr. is known for denying scientific evidence. His first 50 days have seen decisions that undermine science. They weaken the protection of vulnerable populations, risk increasing health inequalities, and threaten public health nationally and internationally. This is the meaning of the slogan “Make America Healthy Again” (https://www.thelancet.com/journals/lanpub/article/PIIS2468-2667(25)00071-4/fulltext).
- All federal experts on HIV prevention in children abroad have been fired. This could affect more than 500,000 children and more than 600,000 pregnant women living with HIV (https://www.nytimes.com/2025/04/08/health/cdc-hiv-mothers.html)
- Trump’s cuts leave Liberia’s healthcare system on the brink due to a lack of medical supplies (https://elpais.com/planeta-futuro/2025-04-07/los-recortes-de-trump-dejan-el-sistema-sanitario-de-liberia-al-borde-del-abismo-por-la-falta-de-suministros-medicos.html)
International Health Policy
- Trump’s trade war and its impact on healthcare
- The pharmaceutical industry “obeys” Trump and begins investing in the US to avoid tariffs. This can be seen in companies such as the Swiss company Novartis, which has announced investments of $23 billion in the US, as well as J&J, which has announced investments worth €50 billion. This could have an impact on Europe, as Europe’s largest export to the US is medicine (https://www.elespanol.com/invertia/observatorios/sanidad/20250413/industria-farmaceutica-obedece-donald-trump-comienza-hacer-inversiones-eeuu-evitar-aranceles/1003743711055_0.html)
- USA
- A dark moment for American science. Right-wing populism contains a strong dose of skepticism about science, at least in certain fields. This could impact public health and the economy, as the American scientific drive was at the heart of its business development. In recent weeks, thousands of employees have been laid off from the health service, as well as from the FDA, CDC, and the National Institutes of Health. This offers opportunities for other countries, primarily European ones, to attract American scientists (https://www.ft.com/content/7ec9304f-1c67-4a41-90f6-4496512c236b)
- The many ways Kennedy is undermining vaccines (https://www.nytimes.com/2025/04/13/health/kennedy-vaccines-confidence-access.html)
- The United Kingdom and the National Health Service
- The British are getting used to seeking cheap healthcare abroad. 431,000 Britons sought medical care abroad in 2023, five times more than a decade ago. These trips were for hair transplants, dental implants, cosmetic procedures, and hip replacements (https://www.economist.com/britain/2025/04/10/the-british-are-learning-to-love-cheap-overseas-health-care)
- Starmer promises a centralized service for scientists to access data, with a £600 million public investment. The service will be hosted at the Wellcome Genome Campus in Cambridge (https://www.ft.com/content/a92834de-9207-4919-94ed-6224896b9749)
- Italy
- The universalism of healthcare in Italy is being questioned. The National Health Service was established in Italy 50 years ago under the principles of universalism. However, a very granular study of the disease burden shows significant variations in this burden across Italian regions, as well as notable variations in services, which seems to question the principles of universalism (https://www.thelancet.com/journals/lanpub/article/PIIS2468-2667(25)00064-7/fulltext)
- WHO
- The WHO warns of the stagnation in the fight against maternal mortality. While the mortality rate fell by 40% between 2000 and 2023, progress has recently slowed (https://www.lemonde.fr/societe/article/2025/04/07/l-onu-alerte-sur-une-stagnation-dans-la-lutte-contre-la-mortalite-maternelle_6592194_3224.html)
- European Union
- Concern and caution regarding a possible pharmaceutical exodus to the United States (https://www.redaccionmedica.com/secciones/industria/europa-preocupada-por-riesgo-de-exodo-pharma-tras-los-aranceles-de-trump-8754)
National Health Policy
- Central Administration Initiatives
- New Drug Law
- Text of the Draft Law submitted for public review (https://www.sanidad.gob.es/normativa/audiencia/docs/APL_MEDICAMENTOS_Y_PRODUCTOS_SANITARIOS.pdf)
- The new bill aims to make dispensing more flexible and save €1.3 billion, which amounts to €23 billion, or 2% of GDP. The new law empowers nurses and physiotherapists to prescribe drugs in very limited exceptions. Prescription by active ingredient is also established (https://elpais.com/sociedad/2025-04-08/el-gobierno-aprueba-un-proyecto-de-ley-del-medicamento-que-flexibilizara-su-dispensacion-y-que-pretende-ahorrar-1300-millones.html)
- Unanimous opposition from the pharmaceutical sector to the new bill. In an unusual move, both pharmacists (Official College of Pharmaceutical Colleges); The three pharmaceutical industry associations (Farmaindustria, AESEG, and Biosim) and the pharmaceutical distribution company FEDIFAR strongly oppose the regulation, particularly the selected prices for off-patent medications, which would change every six months (https://diariofarma.com/2025/04/10/el-sector-farmaceutico-pide-al-unisono-un-cambio-de-rumbo-para-la-ley-de-medicamentos)
- The price reduction for generics pits the Ministry against the industry (https://elpais.com/sociedad/2025-04-09/la-reduccion-del-precio-de-los-medicamentos-genericos-enfrenta-al-ministerio-de-sanidad-con-la-industria-y-con-los-farmaceuticos.html)
- New Drug Law
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- Spain-China Trade Agreement
- Agreement between Spain and China for the export of medical devices and medicines (https://diariofarma.com/2025/04/11/espana-y-china-incluyen-los-productos-sanitarios-en-su-acuerdo-de-exportacion)
- Spain-China Trade Agreement
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- Public Health Agency
- The government is giving the State Public Health Agency a second round of approval. The Council of Ministers resubmits the bill (https://www.diariomedico.com/medicina/politica/gobierno-da-segunda-vuelta-proyecto-ley-agencia-salud-publica.html
- Public Health Agency
- Autonomous community initiatives
- Osakidetza’s offer to retain doctors: €56,629 salary and 28 vacation days (https://diariomedico.com/medicina/politica/oferta-osakidetza-retener-medicos-56629-euros-sueldo-28-dias-vacaciones.html)
- Satisfaction with the NHS in Spain
- Spaniards’ satisfaction with the NHS has dropped by 20% in 4 years, according to FUNCAS (https://diariofarma.com/2025/04/07/funcas-bajan-un-20-en-cuatro-anos-los-espanoles-que-se-declaran-satisfechos-con-el-sns)
Companies
- International News
- Former Novartis subsidiary threatens revenues from one of Bayer’s best-selling drugs (https://www.eleconomista.es/salud-bienestar/noticias/13308484/04/25/la-exfilial-de-novartis-amenaza-los-ingresos-de-uno-de-los-medicamentos-mas-vendidos-de-bayer.html)
- National
- This is how Trump’s tariffs affect Spanish pharmaceutical companies. Although the drugs were initially excluded from the tariffs, Trump’s other statements indicate that they will be included. This would affect Grifols, Rovi, Almirall, and Faes Farma to varying degrees (https://www.expansion.com/empresas/2025/04/12/67f98f5be5fdeafe5f8b45b0.html)
- The Tiritas manufacturer increases the turnover at its large factory in Spain to €130 million (https://www.eleconomista.es/salud-bienestar/noticias/13316007/04/25/el-fabricante-de-tiritas-eleva-a-130-millones-la-facturacion-en-su-gran-fabrica-de-espana.html)
- The Treasury demands €36 million in unpaid taxes from the Israeli pharmaceutical company Teva (https://www.eleconomista.es/actualidad/noticias/13304244/04/25/hacienda-exige-36-millones-en-impuestos-no-pagados-a-la-farmaceutica-israeli-teva.html)
- SERGAS and Povisa sign the new healthcare contract in Vigo for 195 million euros. The hospital will earn 17% more each year under the new agreement. This will serve an estimated population of 116,000 people (https://www.eleconomista.es/salud-bienestar/ultimas-noticias/noticias/13315014/04/25/sergas-y-povisa-firman-el-nuevo-contrato-de-prestacion-sanitaria-en-vigo-por-195-millones-no-es-privatizar-estamos-sergastizando.html)