7 days in healthcare (October 21st-27th, 2024)
Summary
Biomedicine
- A drug that can change the world. Drugs like Ozempic will change the world. First they were for diabetes, then for obesity, now for cardiovascular and kidney diseases, and are being tested for Alzheimer’s and addictions. As they become cheaper and easier to use, they promise to change the lives of more than a billion people. These drugs can produce great social changes, improving productivity and freedom.
- 950 AI devices approved by the FDA. The fact that 950 devices have already been approved argues for the impact of AI in health. Radiology leads the number of approved devices.
- Potential for newborn screening. Genetic sequencing makes it possible to identify dozens of treatable diseases in newborns that escape current screening. A study of 4,000 babies found health problems in 120 ailments compared to 10 with conventional tests.
- The promising future of vaccines for treatment. Curing Parkinson’s, Alzheimer’s or tackling pancreatic cancer. Vaccinologists gathered in Malaga analyse the paradigm shift in serums, intended to cure, not just prevent, diseases. From Alzheimer’s to Parkinson’s, including certain cancers such as pancreatic or lung cancer.
Global Health
- Microplastic pollution. Twenty years after the introduction of the concept of microplastics, we now know better their ecological impact and risks, as well as the risks to human health.
- Climate change, cities and health. More than ever, the climate crisis is a health crisis. It is estimated that 5 million people a year die as a result of suboptimal temperatures, the vast majority (37%) from heat, attributed to changes in temperature due to human action.
- The loss of biodiversity: a health crisis. There are two irrefutable pieces of evidence: that there is a loss of biodiversity and that this generates problems for human health, specifically more infectious diseases.
International health policy
- The shortage of doctors in the USA. Article in the American Journal of Medicine: Congress is called upon to intervene to prevent the US doctor shortage, estimated at 57,259, 79,080, and 81,180 doctors in 2025, 2030, and 2035, respectively.
- Public opinion is asked on how to fix the NHS. The Health Secretary wants to start a national conversation on the issue, asking professionals, experts, and the general public for their opinions.
- Wes Streeting (British Health Secretary) unveils plans for “patient passports” to carry NHS medical records. The idea is that all NHS patients have digital access to their clinical information. It is a step in the line from “analogue to digital”.
- “Mon bilan prévention”, launch of an ambitious device to improve the health of the French. Announced by the President of the Republic in 2022, this would allow access to preventive care at key ages in life: between 18 and 25 years; between 45 and 50; between 60 and 65; and between 70-75. It seems like an important step towards including preventive medicine in the public health system.
- Europe falls behind China in the recruitment of new clinical trials. Clinical trials in Europe have been reduced by half in the last decade, while laboratories seek more simplified regulation in the USA and China.
National Health Policy (Spain)
- Health will be present at the next Conference of Presidents, as stated by the Minister of Territorial Policy and Democratic Memory. Regardless of the result, which will surely not be relevant, it is important that health is on the political agenda.
- Catalonia promotes the joint purchase of medicines to improve the efficiency of the system. Agreement between the ICS, the Unió and the Consorció Sanitari de Catalunya. An important step, equivalent to the great step taken in the USA to allow Medicare to negotiate the price of medicines. This totally decentralised purchase of medicines in the hospital setting is something that does not make sense.
- The new MUFACE agreement divides insurance companies. It seems that DKV is for no, ASISA for yes, and Adelas is in doubt. Among the shareholders of Adeslas, it is said that Mutua is for no, while La Caixa is for yes.
- The POP denounces that waiting lists put lives at risk. It demands urgent solutions. The lives of the most vulnerable patients are being put at risk. In the United Kingdom, the consequences of waiting lists are well analyzed in terms of deaths. There is no reason to think that in Spain they do not have the same consequences.
- The SEMI Congress urges the transformation of the SNS due to the chronicity of pathologies. They understand that home hospitalization must be intensively developed.
- The Catalan EBAs want their model to expand. The president of their association, ACEBA, said that they will once again present proposals for this type of management by professionals. The halt to the expansion of the EBAs in Catalonia, during the time of Marina Gelli, was bad news for everyone. It is certainly not a model that can be generalised to the whole system, but in the face of empty proposals for reform of Primary Care, the EBAs offer a model with excellent results, both in terms of care and satisfaction of professionals. It would be good news if it expanded and not only in Catalonia. Already during the time of the councillor Lasquetty there was an attempt, with the advice of Albert Ledesma, to extend the model in Madrid, unfortunately failed due to the action of the “white tides”.
Companies
- International
- Competition will make anti-obesity drugs better and cheaper. Although NovoNordisk and Lilly are going to dominate the market for a while, many competitors are looming, with cheaper prices.
- Walmart and Amazon threaten pharmacies in the USA in the distribution of drugs. CVS and Walgreens, traditional pharmaceutical chains, are under pressure.
- National
- HM integrates a new centre in Salamanca. With this incorporation the group will have 23 hospitals
Biomedicine
- The Economist Editorial: It’s not just obesity, drugs like Ozempic will change the world. First they were drugs for diabetes, then for obesity, now for cardiovascular and kidney diseases, and they are being tested for Alzheimer’s and addictions. As they become cheaper and easier to use, they promise to change the lives of more than a billion people. These drugs can produce great social changes, improving productivity and freedom (https://www.economist.com/leaders/2024/10/24/its-not-just-obesity-drugs-like-ozempic-will-change-the-world)
- The impact of CRISPR on the discovery of new drugs against cancer. Since its discovery in 2012 as a gene editing tool, this tool is especially useful in cancer (https://www.science.org/doi/10.1126/science.adi6884)
- The 950 AI devices approved by the FDA. The fact that 950 devices have already been approved argues for the impact of AI in healthcare. Radiology leads the number of approved devices (https://medicalfuturist.com/the-current-state-of-fda-approved-ai-based-medical-devices/)
- Genetic sequencing makes it possible to identify dozens of treatable diseases in newborns that escape current screening. A study of 4,000 babies found health problems in 120 ailments compared to 10 with conventional tests (https://elpais.com/salud-y-bienestar/2024-10-24/la-secuenciacion-genetica-permite-identificar-decenas-de-enfermedades-tratables-en-recien-nacidos-que-escapan-al-cribado-actual.html). Access to the original article published in JAMA: https://jamanetwork.com/journals/jama/fullarticle/2825327?guestAccessKey=5344c8b7-0e87-4c88-9660-55b788317c15&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=102424
- Poverty is a cause of schizophrenia, but also a consequence, according to a new study (https://elpais.com/salud-y-bienestar/2024-10-26/la-pobreza-es-causa-de-esquizofrenia-pero-tambien-consecuencia-segun-un-nuevo-estudio.html)
- The future of vaccines: curing Parkinson’s, Alzheimer’s or tackling pancreatic cancer. Vaccinologists gathered in Malaga analyze the paradigm shift of serums, intended to cure, not just prevent diseases. From Alzheimer’s to Parkinson’s, including certain cancers such as pancreatic or lung cancer (https://www.lavanguardia.com/vida/20241025/10048884/futuro-vacunas-curar-parkinson-alzheimer-frente-cancer-pancreas.html)
- Pathological Anatomy: “Molecular diagnosis will transform the way we classify tumors.” Its development goes hand in hand with the development of precision medicine (https://www.consalud.es/profesionales/anatomia-patologica-el-diagnostico-molecular-transformara-forma-en-clasificamos-tumores_150048_102.html)
- The greatest discovery in history made by AI: the origin of more than 160,000 viruses (https://www.eleconomista.es/tecnologia/noticias/13048956/10/24/el-mayor-descubrimiento-de-la-historia-hecho-por-la-inteligencia-artificial-el-origen-de-mas-de-160000-virus.html)
Global Health
- Microplastic pollution. Twenty years after the introduction of the concept of microplastics, we now have a better understanding of their ecological impact and risks, as well as the risks to human health (https://www.science.org/doi/10.1126/science.adl2746)
- Climate change, cities and health. More than ever, the climate crisis is a health crisis. It is estimated that 5 million people die each year as a result of sub-optimal temperatures, the vast majority (37%) from heat, attributed to changes in temperature caused by human action (https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)01934-2/abstract)
- The loss of biodiversity: a health crisis. There is two compelling pieces of evidence: that biodiversity is being lost and that this is causing problems for human health, in particular more infectious diseases (https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02350-X/fulltext#:~:text=Anthropogenic%20environmental%20changes%20including%20changes,arise%20where%20ecosystems%20are%20disrupted.)
- Why heat waves may be more deadly than feared (https://www.nytimes.com/2024/10/25/health/heat-tolerance-climate-change.html#:~:text=Because%20air%20carries%20more%20water,core%20temperature%20starts%20to%20rise.)
International Health Policy
- USA
- The US doctor shortage. Article in the American Journal of Medicine: Congress calls for action to prevent a US doctor shortage, estimated at 57,259, 79,080, and 81,180 in 2025, 2030, and 2035, respectively (https://www.amjmed.com/article/S0002-9343(24)00352-8/fulltext)
- The 2024 US elections and healthcare. JAMA magazine summarises several articles published in the magazine on this topic (https://jamanetwork.com/journals/jama/fullarticle/2825270)
- United Kingdom and the National Health Service
- Pharmaceutical companies give millions to the NHS for matters that have nothing to do with research. BMJ analysis says drug companies pay millions into the NHS, with no clear idea of where the money goes (https://www.bmj.com/content/387/bmj.q2264#:~:text=Feature%20Research-,Pharma%20pours%20millions%20into%20the%20NHS%20for%20non%2Dresearch%20work,money%20is%20being%20spent%20on&text=An%20analysis%20by%20The%20BMJ,what%20the%20payments%20are%20for.)
- How much more money does the NHS need? There is a £4.8bn shortfall in the 2024 budget, without extra funding cuts are inevitable (https://www.nuffieldtrust.org.uk/news-item/how-much-more-money-does-the-nhs-need)
- Public is asked for its opinion on how to fix the NHS. The Health Secretary wants to start a national conversation on the issue, asking professionals, experts and the general public for their opinions (https://www.ft.com/content/c18b4787-a343-4d0a-9a95-23ce740c99ed)
- Wes Streeting (UK health secretary) unveils plans for “patient passports” to carry NHS medical records. The idea is that all NHS patients will have digital access to their medical information. It is a step in the line of “analogue to digital” (https://www.theguardian.com/society/2024/oct/21/wes-streeting-unveils-plans-for-patient-passports-to-hold-all-medical-records)
- Tens of thousands of UK dementia patients in a clinical trial on Alzheimer’s (https://www.theguardian.com/society/2024/oct/24/tens-of-thousands-of-uk-dementia-patients-to-be-enrolled-in-clinical-trials)
- NHS staff constantly use WhatsApp to share private clinical information (https://www.ft.com/content/c19fe8bf-0fd3-42bf-8e07-8f4e5d26ec25)
- France
- Tribune in Le Monde: “The creation of a public pharmaceutical company would make it possible to guarantee stable production of medicines essential medicines”, in response to the abandonment of these drugs by pharmaceutical companies (https://www.lemonde.fr/idees/article/2024/10/23/doliprane-la-creation-d-une-capacite-pharmaceutique-publique-permettrait-de-garantir-une-production-stable-de-medicaments-essentiels_6358439_3232.html)
- “Mon bilan prévention”, the launch of an ambitious plan to improve the health of the French. Announced by the President of the Republic in 2022, this would allow access to preventive care at key ages in life: between 18 and 25 years old; between 45 and 50; between 60 and 65; and between 70-75 (https://sante.gouv.fr/actualites/presse/communiques-de-presse/article/mon-bilan-prevention-lancement-d-un-dispositif-ambitieux-pour-ameliorer-la)
- Germany
- A first case of mpox detected in Germany (https://fr.africanews.com/2024/10/23/mpox-un-nouveau-variant-decouvert-en-allemagne/)
- Portugal
- The Amancio Ortega Foundation supports proton therapy in Portugal (https://www.elespanol.com/quincemil/vivir/salud/20241025/fundacion-amancio-ortega-dona-millones-primer-plan-protonterapia-portugal/896160535_0.html)
- Europe
- Europe falls behind China in recruiting new clinical trials. Clinical trials in Europe have halved over the past decade as drugmakers seek more streamlined regulation in the US and China (https://www.ft.com/content/3d861acb-8e7d-4157-b845-81124254da8a)
National health policy
- Initiatives of the central government
- Health will be present at the next Conference of Presidents, as stated by the Minister of Territorial Policy and Democratic Memory (https://www.consalud.es/politica/sanidad-estara-presente-en-proxima-conferencia-presidentes_150086_102.html)
- Initiatives and news from the autonomous communities
- Historic commitment, several communities prioritize health in the 2025 budgets, this occurs in La Rioja, Galicia, Castilla y León and Castilla-La Mancha (https://www.consalud.es/autonomias/apuesta-historica-en-sanidad-presupuestos-2025-priorizan-salud-en-varias-ccaa_150259_102.html)
- Martínez hopes to close the diagnostic phase of the Basque Health Pact on October 30 (https://www.consalud.es/autonomias/pais-vasco/martinez-espera-cerrar-fase-diagnostico-pacto-vasco-salud-30-octubre_149966_102.html)
- La Rioja, headquarters of the innovative clinical trials unit against cancer (https://www.eldiario.es/sociedad/rioja-sera-sede-ensayos-clinicos-farmacos-cancer-norte-espana_1_11764327.html)
- Catalonia promotes the joint purchase of medicines to improve the efficiency of the system. Agreement between the ICS, the Unió and the Consorció Sanitari de Catalunya (https://www.consalud.es/industria/cataluna-impulsa-compra-conjunta-medicamentos-mejorar-eficiencia-sistema_150065_102.html)
- Catalan doctors ask for an end to impositions and threats regarding the use of Catalan (https://www.eldebate.com/espana/cataluna/20241025/medicos-catalanes-piden-generalitat-paren-imposiciones-amenazas-catalan_238877.html)
- The new Clínic hospital in Barcelona will open in 2035 and will have a metro stop (https://www.expansion.com/catalunya/2024/10/21/6716ad3c468aebdb588b4588.html)
- Castilla-La Mancha will allocate 3.8 billion euros of its 2025 budget to healthcare (https://www.consalud.es/autonomias/castilla-la-mancha/castilla-la-mancha-destinara-3800-millones-euros-sanidad-en-sus-presupuestos-2025_150093_102.html)
- Asturias approves 349 specialist nursing positions (https://diariomedico.com/enfermeria/politica/asturias-aprueba-creacion-349-primeras-plazas-enfermeria-especialista.html)
- MUFACE
- The new MUFACE agreement divides insurance companies. It seems that DKV is for no, ASISA for yes, and Adelas is in doubt. Within Adeslas, the Mutua is for no, while La Caixa is for yes (https://theobjective.com/economia/2024-10-25/nuevo-concierto-muface-divide-companias-aseguradoras/)
- Questions from the AIREF survey to MUFACE officials (https://www.epe.es/es/sanidad/20241023/preguntas-airef-mandado-accionarios-muface-listas-de-espera-medico-cabecera-110194983)
- Platform of Patient Organizations (POP)
- The POP denounces that waiting lists put lives at risk. It demands urgent solutions. The lives of the most vulnerable patients are being put at risk (https://www.larazon.es/sociedad/plataforma-organizaciones-pacientes-denuncia-que-crisis-listas-espera-pone-riesgo-vidas_20241024671a8df72914190001e060b9.html)
- Congress of the Spanish Society of Internal Medicine (SEMI)
- he SEMI Congress urges the transformation of the SNS due to the chronicity of pathologies. They understand that home hospitalization must be intensively developed (https://www.larazon.es/salud/urge-transformar-sns-cronicidad-patologias_20241026671a4f2dd0584100016f768b.html)
- Spain: European leader in clinical trials
- Europe places Spain as the leader in clinical trials on the continent. Despite the drop in the number of clinical trials in Europe, apparently due to regulatory problems, Spain is the leader within Europe, surpassing Germany (https://www.somospacientes.com/noticias/carrusel-de-portada/espana-se-consolida-como-lider-europeo-en-ensayos-clinicos/). Access to the original document: https://www.efpia.eu/media/o2gjnmfu/efpia_ve_iqvia_assessing-the-clinical-trial-ct-ecosystem.pdf
- Health expenditure in Spain
- Health expenditure in Spain reached 134,023 million euros in 2022, its historical maximum, reaching 9.95% of GDP (during the pandemic it reached 11%). Of this figure, 74.21% was financed by the public sector, with a growth of 4.85% compared to 2021 (https://diariofarma.com/2024/10/21/el-gasto-sanitario-en-espana-alcanzo-134-023-millones-de-euros-en-2022-un-995-del-pib)
- EBA (self-management in primary care)
- The Catalan EBAs want their model to expand. The president of their association, ACEBA, said that they will once again present proposals for this type of management by professionals (https://diariomedico.com/medicina/politica/eba-autogestion-catalanas-quieren-lograr-modelo-extienda.html)
- Large increase in Medical Schools
- The unstoppable demand for Medicine boosts the Faculties by 37%. In the 2019-20 academic year there were 41 centers, now there are 56 (https://www.redaccionmedica.com/secciones/estudiantes/la-demanda-imparable-de-medicina-dispara-las-nuevas-facultades-un-37–3586)
Companies
- International news
- Competition will make weight loss drugs better and cheaper. Although NovoNordisk and Lilly will dominate the market for a while, there are many competitors on the horizon, with cheaper prices (https://www.economist.com/business/2024/10/24/competition-will-make-weight-loss-drugs-better-cheaper-and-bigger?utm_medium=cpc.adword.pd&utm_source=google&ppccampaignID=18151738051&ppcadID=&utm_campaign=a.22brand_pmax&utm_content=conversion.direct-respons)
- Walmart and Amazon threaten pharmacies in the USA in the distribution of medicines. CVS and Walgreens, traditional pharmacy chains, under pressure (https://www.ft.com/content/a0fb7bee-a8f6-4e33-b07b-e9aa2f43edd7)
- McDonald’s suffers on the stock market after a death and several people affected by hamburgers contaminated by Escherichia coli (https://www.ft.com/content/e92b9f55-8bfc-4f2d-af4c-48639b4e58b5)
- Sanofi exceeds revenue forecasts due to early vaccine sales (https://www.plantadoce.com/empresa/sanofi-supera-las-previsiones-de-facturacion-por-las-ventas-tempranas-de-vacunas)
- Philips presents AI-based echocardiography (https://www.redaccionmedica.com/secciones/tecnologia/philips-presenta-soluciones-innovadoras-de-ecocardiografia-basadas-en-ia-4732)
- The life sciences market is experiencing tremendous growth, according to a report by Markets and Markets. It is expected to reach $61.94 billion by 2029, with a compound annual growth rate of 11.7%. The reason is advanced analytical solutions, AI and automation (https://www.consalud.es/salud35/internacional/mercado-ciencias-biologicas-analisis-tendencias-proyecciones-hasta-2029_149678_102.html)
- UnitedHealth suffers the largest cyberattack in the history of healthcare in the USA (https://www.consalud.es/salud35/internacional/unitedhealth-sufre-mayor-ciberataque-en-historia-atencion-medica-ee-uu_150224_102.html)
- National
- HM integrates a new center in Salamanca. With this addition, the group will have 23 hospitals (https://www.plantadoce.com/empresa/hm-hospitales-integra-un-nuevo-centro-en-castilla-y-leon)
- The medical supplies market in Spain reached 1,910 million in 2023, according to DBK, a 3.2% growth compared to the previous year: Purchases abroad amounted to 2,677 million euros, 6.6% more than in the previous year (https://www.plantadoce.com/entorno/el-mercado-de-material-medico-alcanzo-los-1910-millones-de-euros-en-2023#:~:text=Roche-,El%20mercado%20de%20material%20medico%20alcanzó%20los%201.910%20millones%20de,2%20%25%20respecto%20to%20exercise%20previous.)
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