Posts

7 days in healthcare (March 18th-24th, 2024)

 

Summary

From the point of view of Biomedicine, the transplant to a man of a genetically modified pig kidney stands out, a medical milestone that could lead to dialysis being declared obsolete, which would be an extraordinary advance and an improvement in the quality of life for hundreds of thousands of patients, currently dependent on the machine several times a week for their survival. Also notable is the beginning of a clinical trial on a vaccine for tuberculosis. The current BCG vaccine offers protection to infants and young children, but does not protect adults and adolescents from pulmonary tuberculosis. If the results are good, this vaccine can be transformative.

As far as Global Health is concerned, a study warns of serious declines in birth rates globally, which will mean that by 2050 it will fall below population replacement, which will have important social and labor changes.

Regarding International Health Policy, a great paradox in the USA, although abortion is prohibited in 14 states and restricted in many others, in 2023 there were more abortions than ever, many of them non-instrumental and through the abortion pill, already responsible of 60% of abortions. China is facing a population decline, a phenomenon that has already begun. The one-child policy, in force for 36 years, is only one of the causes of this phenomenon. The European Union is advancing in the approval of pharmaceutical legislation, contemplated with reluctance by both the EFPIA and Medicines for Europe (the two large European pharmaceutical associations). The Lancet sees the upcoming European elections as an opportunity to put health policy higher on the EU agenda.

If we talk about National Health Policy (Spain), three important initiatives of the Ministry of Health: anti-smoking plan, modification of the medical guard regime and waiting lists. In all three cases there may be problems due to the powers and regulations of the autonomous communities. From the point of view of the regions, the OPE of Asturias stands out, which brings together 19,000 candidates. Although logically, temporality was and is a serious problem of public healthcare, which needed a solution, the way to do it through macro-OPE’s (consolidating the position in property, and with hegemony of the administrative and union logic, above the professional and autonomy of organizations) does not seem to be the best. This type of mass examination is more reminiscent of previous calls for the “military service”, when it was in force, than the professional selection for complex organizations, in which the professional qualification, the needs of the different organizations, the projects of the services, etc. should be taken into account.

As for Companies, on an international level, China is seen as the large market for anti-obesity drugs. Bayer wants to renew its portfolio, entering into cell and genetic therapies. As for Spain, the CNMV has released its report on Grifols, with several objections to its accounts. Faes Farma is preparing to grow in Latin America. For its part, DKV, the health insurer, wants to concentrate on group insurance.

Biomedicine

Global Health

International health policy

National health policy

Companies

7 days in healthcare (May 8th-14th, 2023(

 

 

Summary

From the point of view of Biomedicine, it is worth pointing out the expanded “pan-genomic” base, which significantly increases the letters of the DNA, which, apparently, will make it possible to improve the typing and treatment of certain diseases. Promising results of mRNA technology in pancreatic cancer. Potential of stool transplants against some bacteria not sensitive to antibiotics.

As far as Global Health is concerned, although covid is no longer a global emergency, the truth is that, as the WHO itself shows, the disease continues to kill and change.

Regarding International Health Policy, it is worth highlighting the great news coming from the British government, which will allow pharmacies to prescribe certain medications, as well as the contraceptive pill. The objective of the measure is to significantly reduce the number of visits to the primary doctor. In France, patients, faced with overloaded doctors, turn to self-medication. Euthanasia is already legal in Portugal. Great battle in Chile between the Boric government and the Isapres (Chilean health insurers). In a bill, the government, in order to respond to an erga omnes ruling (of universal application) of the Courts, proposes the payment by insurers of alleged amounts for overpayments, which would make the model unfeasible. The Association of Isapres has reacted with a harsh note, answered no less harshly by government spokesmen. Health and specifically the role of the Isapres, at the center of the political debate in Chile.

If we talk about National Health Policy (Spain), the most important news is the proposals by various medical associations (IMAS Foundation, FACME, General Council of Medical Associations) for a decalogue of proposals to reform the SNS, which they consider in total crisis, before the next legislature. New governance; new management model; citizen/patient and professional participation; measurement of results and transparency; new care model; digital transformation according to the citizen’s digital clinical history model, are some of the most important measures. We only have to congratulate those responsible for this initiative, which contrasts so much with the limited and timid proposals put forward by the majority political parties. To those parties (PSOE and PP) the proposals were raised in a meeting. The only possible consideration is whether a reform of the public system is possible without mentioning a limited and selective co-payment, the absence of which we are the exception in Europe, as well as the non-consideration of the private sector in that reform. Looking the other way from the private sector has never produced good results. On the other hand, the document emphasizes its proposal for changes in the management and care model, governance, the participation of citizens/patients and professionals, and transparency. But he doesn’t mention financing at all. Although financing as an isolated reform (which is very common to consider) would not solve much, this issue has specific problems. Having made these qualifications, as a whole it is a splendid document, a must-read. The Constitutional Court publishes the ruling declaring the 2010 law on abortion deadlines legal. A study in Catalonia shows that the rich wait less on the lists of Catalan public hospitals than the rest of the population, something that had already been demonstrated in the UK on the NHS. The CEOE-union agreement includes the control of sick leave by Mutual Societies, something whose real scope will have to wait to see its effects. The truth is that absenteeism had increased a lot in recent times.

In the field of Companies, at the international level, drugs for weight loss point to an area of great economic interest for the pharmaceutical industry. In Spain, the most striking thing is Fresenius’s intention to get rid of the part of Quirón in Latin America, as well as the fertility company Eugin. Mutua Madrileña and El Corte Inglés launch medical insurance under the Adeslas brand.

Biomedicine

Global Health

International Health Policy

  • Chili
    • The Boric government against the Isapres (private health insurance companies in Chile). In a bill, the government, in order to respond to an erga omnes ruling (of universal application) of the Courts, proposes the payment by insurers of alleged amounts for overpayments, which would make the model unfeasible. Hard note from the Association of Isapres, which has obtained a no less harsh response from the Government. (http://www.isapre.cl/images/PDF/Declaracion_Prensa_19_abril_VFdocx_1.pdf)

National health policy

Companies

 

 

7 days in healthcare (December 26th, 2022-January 1st, 2023)

 

 

Summary

From the point of view of Biomedicine, it is worth noting the ambitious project of the United Kingdom “Our Future Health”, which aims to place this country at the forefront of genomic research, and which seeks to carry out genetic analyzes of 5 million adult British volunteers, then looking at the correlation with lifestyles and medical records. Undoubtedly, this project will allow us to advance a lot in the knowledge of a wide variety of diseases.

With regard to Global Health, great concern in the world, since the large number of cases in China increase the probability that new variants will appear. There is no doubt that the covid – which had appeared, artificially or naturally, in China – has entered a new phase in which the epicenter is once again China.

Regarding International Health Policy, countries are preparing to put control measures at airports and borders against travelers from China, although the ECDC sees this type of control as unfounded and the EU has not adopted a common policy. Joschka Fischer (former – German Foreign Minister) publishes an in-depth article, whose conclusion is that, in contrast to what had previously been said that authoritarian regimes that do not depend on public opinion can impose drastic and effective measures in crisis situations such as covid, experience has shown that liberal democracies are more effective than autocracies in dealing with these situations. Great controversy in the European Union over the claim of the pharmaceutical industry to agree to produce new antibiotics, under the condition of increasing the patent term of certain drugs.

If we talk about National Health Policy (Spain), Spain has approved airport control measures to control travelers from China, which will be in force between December 31, 2022 and February 15, 2023. Primary Care doctors have opposed the hiring of doctors without MIR training, since this seems more like an opportunistic measure than addressing the underlying problems of Primary Care. The central government, so little fond of publishing and preparing expert analyzes on the covid management, instead presents a self-assessment on its management. According to this report “Cumpliendo” (“Fulfilling”) 64% of the health promises have already been fulfilled and 35% are in process. Bearing in mind that none of the structural healthcare problems have been addressed (personnel regime, management model, governance, accessibility and waiting lists, etc.) this self-assessment seems to us grated on complacency and even propaganda. Unless the promises -which are said to have been fulfilled- have nothing to do with the real problems of the sector. An interesting initiative from the private sector through the IDIS Foundation, which announces the start-up of a pilot on interoperability, should be highlighted. The fact that companies that compete with each other -both from the insurance and provisioning fields- agree on the interoperability of medical records is something that deserves to be highlighted.

In the field of Companies, the American Congress has taken an unusual decision: criticize the FDA for its inadequate collaboration with Biogen for the approval of the drug against Alzheimer’s. At the national level, Atrys continues its growth, both in Spain and abroad (United Kingdom, Middle East and Latin America).

Biomedicine

Global Health

International Health Policy

National health policy

Companies

 

 

 

7 days in healthcare (25th-31st July, 2022)

 

Summary

From the point of view of biomedicine, it should be noted that the origin of acute childhood hepatitis has been discovered, it turns out to be due to a co-infection of two viruses, ruling out covid as the cause of this disease. Major advances by a group of Yale scientists in the treatment of brain tumors, specifically aggressive glioblastoma multiforme, using molecules that attack tumor DNA. Deep Mind (a company of the Alphabet group, parent of Google) launches an algorithm capable of identifying the structure of proteins. It seems that this advance may be of great importance for the discovery of new drugs.

As far as Global Health is concerned, air pollution is a public health emergency, according to the British Medical Journal. The WHO reaches an agreement on a treaty on pandemics, which should be agreed in May-2024.

Regarding international health policy, mention should be made of the declaration by the WHO of monkeypox as a global public health emergency, which is justified by the existence of more than 17,300 cases in more than 70 countries. It seems that it is confirmed that covid-19 originated in the live animal market in Wuhan (China).

If we talk about national health policy (Spain), two deaths in Spain as a result of monkeypox (in both cases due to encephalitis). At the present time there is only one other case of death from this disease in Brazil. The incidence of covid-19 drops very significantly, moving us away from the peak of the seventh wave.

In the field of companies, it should be noted that Fujijilm is going to be transformed into a health company. Teladoc’s notable financial losses. Vivalto Santé, an important French group, acquires the property of Ribera through the sale of Centene Corporation.

Biomedicine

Global Health

International health policy

National health policy

Companies

 

7 days in healthcare (May 23th-29th, 2022)

 

 

Summary

From the point of view of biomedicine, the most important are the advances in the study of the microbiota, published in the journal Science.

As far as Global Health is concerned, the tragic mistake of the donation of vaccines by Europe should be highlighted, since many of those sent were close to expiration. Reappearance of polio in Africa, always worrying.

Regarding international health policy, the European health agency asks governments to be prepared against possible vaccination against monkeypox. Health bursts into the spotlight at the Davos Economic Forum.

If we talk about national health policy (Spain), Spain joins the European system for the purchase of vaccines against monkeypox. The MIR call leaves 200 vacancies for family doctors. An emergency situation is addressed, but not the underlying problem: the unattractive nature of these places.

In the field of companies, it should be noted that, according to Expansión, private insurance customers are dissatisfied with the massive use of the service. Between this and the unhappiness of both doctors and providers with the fees, it seems that significant changes are coming in this sector.

Biomedicine

Global health

International health policy

  • Monkeypox

o The European health agency asks governments to be prepared for vaccination against monkeypox (https://www.ft.com/content/11df80f5-32d5-4bb3-8215-420574f276c4)

o The monkeypox virus, what we know so far that alarms countries (https://www.ft.com/content/d951bd2b-0470-4d74-827d-0c06d9bf5056)

o Monkeypox, more than 180 cases outside Africa, countries prepare to vaccinate (https://www.lemonde.fr/planete/article/2022/05/25/variole-du-singe-plus-de- 180-cas-confirmes-hors-d-afrique-des-pays-se-preparent-a-vacciner_6127608_3244.html)

o A study published in The Lancet points to an antiviral as a possible treatment for monkeypox (https://www.eldiario.es/sociedad/estudio-publicado-the-lancet-senala-antiviral-posible-tratamiento-viruela- monkey_1_9018642.html)

  • COVID-19

o Lessons from Japan on dealing with covid, since this country had six waves and the number of cases and deaths per capita has been lower than other G7 countries, despite having an aging and highly concentrated population (https ://media.nature.com/original/magazine-assets/d41586-022-01385-9/d41586-022-01385-9.pdf)

o More than 1 in 5 COVID survivors may develop long covid in the United States (https://www.nytimes.com/2022/05/24/health/long-covid-infections.html)

o Pfizer warns of constant waves of covid-19, while complacency grows (https://www.ft.com/content/8244af52-26ba-4676-961a-c57f1d4892e8)

o What justifies the zero-covid policy in China?, an analysis by Zhang Jun, director of the China Center for Economic Studies in Shanghai (https://www.project-syndicate.org/commentary/shanghai-lockdown-why-china -keeps-its-zero-covid-strategy-by-zhang-jun-2022-05)

o A study suggests that women are twice as likely to suffer from persistent covid (https://www.ft.com/content/ea2d58c5-ae62-442c-b721-364c95852209)

  • Other themes

o Health bursts into the spotlight at the return of the Davos Economic Forum, with the presence of Bill Gates, the CEO of Pfizer and the president of AstraZeneca, among others (https://www.plantadoce.com/entorno/la- health-breaks-in-as-protagonist-in-the-return-of-the-davos-economic-forum.html)

o Tedros Adhanom Ghebreyesus re-elected as WHO Director General (https://www.ft.com/content/75de7a67-f850-4fe2-8911-8f6237f38514)

o Oklahoma Governor signs law strictly banning abortion (https://www.theguardian.com/us-news/2022/may/26/oklahoma-strictest-abortion-ban-law-us-governor)

National health policy (Spain)

  • Monkeypox

o At least six countries have detected cases of monkeypox in travelers from Spain (https://elpais.com/sociedad/2022-05-28/al-menos-seis-paises-han-detectado-casos-de- monkeypox-in-travelers-from-spain.html)

o 41% of monkeypox cases are in Spain (https://www.larazon.es/sociedad/20220523/6t2hw3xhhveq3e7oho5hnj3zxa.html)

o Spain will enter the European system for the purchase of the monkeypox vaccine (https://www.diariofarma.com/2022/05/25/espana-entrara-en-la-compra-centralizada-de-la -eu-to-deal-with-monkeypox)

  • COVID

o The cumulative incidence, down (728.2 cases in the last 14 days; there were 848 the previous Friday. Hospital occupancy due to covid: 5.6%; ICUs: 4.2%) (https://www.consalud .es/patients/special-coronavirus/covid-19-spain-coronavirus-data_115366_102.html)

  • Regulatory announcements

o New Framework Statute, at the table of the Advisory Council on June 2 (https://www.redaccionmedica.com/secciones/ministerio-sanidad/nuevo-estatuto-marco-y-10-puntos-mas-al-consejo- advisory-of-june-2-5764)

o A new draft of the Preliminary Draft Law is published, which modifies various regulations to consolidate the equity, universality and cohesion of the National Health System, after its approval in the Interterritorial Council of April 2022 (https://www.diariofarma .com/2022/04/06/el-cisns-da-luz-verde-a-la-ley-de-equidad), held in Toledo. In relation to the previous version of 11/15/2021, more requirements are introduced for agreement, incorporating the concept of “effective cost” previously established and reviewable by the Administration

  • Other themes

o The Ministry of Health marks November for the new palliative strategy (https://www.redaccionmedica.com/secciones/ministerio-sanidad/sanidad-marca-noviembre-para-activar-la-nueva-estrategia-de-paliativos- 6597)

o The public debt to suppliers amounts to 2,000 million (https://www.diariofarma.com/2022/05/23/la-deuda-publica-a-proveedores-sanitarios-asciende-a-2-000-millones)

o Warning from Brussels to Spain due to the “shortage” of health professionals and primary care financing (https://www.consalud.es/politica/toque-bruselas-espana-por-escasez-sanitarios-finacion-primaria_115145_102.html)

o Podemos takes the “deprivatization” of the SNS to Congress (https://www.redaccionmedica.com/secciones/parlamentarios/podemos-aprieta-al-psoe-llevando-al-congreso-la-desprivatizacion-del-sns-1224)

o The lack of family doctors worsens as the MIR call leaves 200 places vacant (https://elpais.com/sociedad/2022-05-24/la-falta-de-medicos-de-familia-se-agrava- la-convocatoria-de-mir-deja-200-plazas-vacantes.html), for which it is agreed to increase the number of MIR vacancies for non-EU people to fill the vacancies (https://www.elmundo.es/ciencia- y-salud/salud/2022/05/25/628e86d3e4d4d85f418b45e6.html

Companies

  • International News

o Pfizer intends to obtain approval in the USA for the covid vaccine for children under 5 years of age (https://www.ft.com/content/48c88652-502c-4b33-9866-589eeafcf302)

o Medtronic and DaVita announce the creation of a kidney health technology company (https://www.consalud.es/ecsalud/internacional/medtronic-davita-anuncian-creacion-empresa-tecnologia-salud-renal_115348_102.html)

o The USA will deploy the Bavarian Nordic monkeypox vaccine (https://www.consalud.es/ecsalud/internacional/eeuu-desplegara-vacuna-contra-viruela-mono-bavarian-nordic-entre-poblacion-vulnerable_115091_102. html)

o The IFPMA (global employers association of pharmaceutical manufacturers) proposes 10 measures to fight the next pandemic (https://www.diariofarma.com/2022/05/25/la-ifpma-propone-10-medidas-para-luchar- against-the-next-pandemic)

  • National News

o Grupo Juste, a Spanish pharmaceutical company that turns 100 (https://www.redaccionmedica.com/secciones/industria/una-farmaceutica-espanola-cumple-100-anos-7009)

o Esteve intends to double its turnover, reaching 1,000 million euros (https://cincodias.elpais.com/cincodias/2022/05/26/companias/1653591656_508050.html)

o Clients of private health insurance, disappointed by the mass use of the service (https://www.expansion.com/empresas/banca/2022/05/28/6290b63c468aebbe018b45d8.html)

o The private sector of assisted reproduction moves 500 million in 2021, 9% more than in 2020 (https://www.plantadoce.com/entorno/el-sector-privado-de-reproduccion-asistida-mueve-500-millones -in-2021-a-9-more-than-in-2020.html)

o FENIN registers a 27% decrease in investment in 2021 (https://www.actasanitaria.com/tecnologia/fenin-registra-descenso-27-en-inversion-tecnologia-sanitaria_2002610_102.html)

o Sanitas and the San Pablo CEU University sign an agreement for the training of health professionals (https://www.servimedia.es/noticias/sanitas-universidad-ceu-san-pablo-firman-acuerdo-para-formacion-profesionales- assistance-future/3406605)

o Malaga will have a new public hospital in 2023, after the agreement with the Pascual group (https://www.vidaeconomica.com/2022/05/hospital-malaga/)

 

 

 

 

 

7 days in healthcare (March 14-20, 2022)

 

SUMMARY

From the point of view of biomedicine, to highlight the new treatment for malaria in children; the new variant “Delatacron”, similar to the “ómicron”; and, the possibilities of artificial intelligence to accelerate the appearance of new medicines. We would like to underline the studies promoted by Valentín Fuster on ultrasound of the neck and groin arteries and their possibilities of detecting the risk of myocardial infarction and stroke to be promising, although it is a topic that has been talked about for a long time without much results.

Regarding Global Health, an interesting editorial in the British Medical Journal, entitled climate change, pandemic and war: an uncontrolled multi-crisis, since it seems that in this decade of the 21st century all the problems have accumulated; the verification that the low level of vaccinations in Africa is not so much due to the low level of vaccines, but rather due to the difficulties of reaching the population; interesting report on Nigeria and the problems of its health system.

In terms of international health policy, the problems of Asia’s “covid zero” strategy are noteworthy, which gave so much political return to the Chinese regime, presenting its low mortality successes and comparing them with the high mortality rates of other countries in the world ( United States, Brazil, United Kingdom, India, etc.). It seems that the “ómicron” variant, due to its contagiousness, is not easily approachable with the “covid zero” strategy, since that would lead to massive confinements in China. Resurgence of covid cases in Europe and Asia, which coincides with a relaxation of control measures.

If we talk about national health policy (Spain), it should be noted that the incidence of covid is growing, while the measures are relaxed, although there is concern in the Ministry of Health about a possible new wave of covid at the gates of Easter. Very important COFARES report on the pharmacy sector, proposing many innovative measures, which contrasts with the usual narcissism and laudatory speeches about the “Mediterranean model of pharmacy”, so liked by some professional representatives. Primary Care is trying to get back to normal, although with a thousand fewer doctors than before the pandemic. The birth rate in Spain is at historic lows, which is a serious problem. The Council of Dentists, in reporting that 34 million Spaniards have cavities, presents us with the reality of poor dental care in our country. A revolution in the use of biosimilars is coming, given the large number of biological medicines that will lose their patent in the coming years.

In the field of companies, it should be noted that Pfizer and BioNTech have requested authorization in the United States for a second “booster” for older Americans. Grifols bets on a vaccine against Alzheimer’s. HIPRA, the veterinary pharmacy company until now, hopes to start marketing its vaccine against covid in June.

BIOMEDICINE

GLOBAL HEALTH

INTERNATIONAL HEALTH POLICY

  • COVID

o The “ómicron” variant is changing China’s “zero covid” strategy, at the moment more than 40 million Chinese are suffering some type of confinement, which is tolerated by the remaining 1.4 billion who lead normal lives. The legitimacy of the party is given by the low mortality. We’ll see if that can be sustained with the “omicron” (https://www.economist.com/china/2022/03/19/omicron-is-changing-chinas-covid-strategy)

o China reports the first deaths from covid in more than a year (https://www.nytimes.com/live/2022/03/18/world/covid-19-mandates-cases-vaccine)

o Shanghai, possible confinement, after the discovery of 150 new cases of covid (https://www.ft.com/content/659a5337-681b-4ef2-a9ac-db9aaaa78cef)

o Concern that new lockdowns in China may disrupt supply chains (https://www.economist.com/finance-and-economics/will-chinas-covid-lockdowns-add-to-strains-on-supply- chains/21808193)

o Resurgence of covid cases in Europe and Asia, infections have risen 8% worldwide, but they are skyrocketing in Vietnam and Germany (https://www.larazon.es/sociedad/20220317/z4bkdrxn2vddtcbvhi5equn45e.html)

  • Other issues

o According to an American study (Health Affairs), hospitals differ in their services depending on whether they are for-profit, non-profit or government-owned, with the former tending to offer more profitable services and discontinue the others (https://www.healthaffairs. org/doi/epdf/10.1377/hlthaff.2021.01115)

NATIONAL HEALTH POLICY (SPAIN)

  • COVID

o Latest report: the incidence of covid rise and 287 deaths, in Friday’s report (since Tuesday) (https://www.consalud.es/pacientes/especial-coronavirus/covid-19-espana-registra-64597 -cases-287-deaths-ia-upload-44580-points_111800_102.html)

o The new plan against covid will put an end to the isolation of positives (https://www.lavanguardia.com/vida/20220319/8136758/nuevo-plan-covid-pondra-aislamientos-positivos.html)

o The Ministry of Health fears the arrival of a new wave of covid at the gates of Holy Week (https://www.elespanol.com/espana/20220314/sanidad-llegada-septima-covid-puertas-semana-santa/656934435_0 .html)

o Paxlovid, the anticovid treatment promised by Sánchez, has not yet reached patients (https://www.elmundo.es/ciencia-y-salud/salud/2022/03/17/623244e021efa054348b458d.html)

  • Other themes

o Spain was left out of the top 10 in public health spending in 2020, according to a report made public by Eurostat and spent an average of 600 euros less per inhabitant than the EU average (https://www.consalud.es/politica/espana- top-10-ue-public-expenditure-health-2020_111467_102.html). To access the Eurostat report: https://ec.europa.eu/eurostat/databrowser/view/GOV_10A_EXP__custom_2243551/bookmark/table?lang=en&bookmarkId=8df11907-86e8-4f5b-a62e-a7d09828e303)

o Important COFARES report: pharmacist skills in the 21st century, proposing digitization, home delivery, legal changes and the sustainability of the pharmacy model (https://www.consalud.es/profesionales/profesionales-analizan- evolution-pharmacy-role-pharmacist_111660_102.html)

o The Ministry of Health and the regions coordinate health care for refugees from Ukraine (https://www.diariofarma.com/2022/03/18/sanidad-y-las-cc-aa-garantizan-la-atencion- health-for-refugees-from-ukraine)

o The Ministry of Health puts the average time to approve a drug at “9 months” (https://www.consalud.es/politica/ministerio-sanidad/sanidad-asegura-la-media-espana-aprobar-medicamento-9- months_111648_102.html)

o The flu enters Spain with force (https://www.lavanguardia.com/vida/20220317/8130742/gripe-fuerza-espana.html)

o Primary Care is trying to get back to normal, with a thousand fewer doctors than before the pandemic (https://elpais.com/sociedad/2022-03-20/la-atencion-primaria-intenta-volver-a-la- normality-with-a-thousand-less-doctors-than-before-the-pandemic.html)

o The birth rate in Spain, at lows not known in several centuries, according to a study by the San Pablo CEU University (https://www.eldebate.com/sociedad/20220315/pandemia-apenas-pasa-factura-natalidad-espana. html)

o A total of 34 million people in Spain have cavities, according to the General Council of Dentists (https://www.actasanitaria.com/politica-y-sociedad/total-34-millones-personas-en-espana-tienen- caries_2001822_102.html)

o The Ombudsman receives 2,300 health complaints in 2021, according to the report presented (https://www.defensordelpueblo.es/informe-anual/informe-anual-2021/)

o La Paz, on October 12 and Gregorio Marañón among the 100 best hospitals in the world, according to the classification prepared by Newsweek magazine (https://www.elmundo.es/madrid/2022/03/14/622e4da7e4d4d894118b45c8.html )

o Incorporating 6,000 doctors in primary care would cost 358 million euros, according to the Collegiate Medical Organization (https://www.elmundo.es/ciencia-y-salud/salud/2022/03/14/622df5e7fc6c83c80d8b4583.html)

o Mariano Esteban’s covid vaccine will not continue the clinical phase in Spain (https://www.diariomedico.com/medicina/enfermedades-infecciosas/empresas/la-vacuna-de-la-covid-de-mariano-esteban -csic-will-not-continue-the-clinical-phase-in-spain.html)

o Spain needs a plan for the second revolution in biosimilars, since one hundred biological drug patents expire between 2024 and 2029 (https://cincodias.elpais.com/cincodias/2022/03/16/companias/1647452966_841014.html)

COMPANIES, EMPLOYERS AND OTHER AGENTS IN THE SECTOR

  • International News

o Moderna supplies 70 million additional doses of its vaccine to Japan (https://www.plantadoce.com/empresa/moderna-suministra-70-millones-de-dosis-addicionales-de-su-vacuna-anti-covid- 19-a-japan.html)

o Pfizer and BioNTech request authorization for a second “booster” for older Americans (https://www.nytimes.com/2022/03/15/us/politics/pfizer-second-booster-shot-older-americans.html )

o AstraZeneca, prepared not to continue with the efforts to obtain authorization in the USA for the covid vaccine (https://www.ft.com/content/e1edb2b2-0e12-4c83-9257-eeeb2ba29267)

  • National News

o Grifols bets on the Alzheimer’s vaccine and ends phase II of clinical trials (https://www.plantadoce.com/empresa/grifols-apuesta-por-la-vacuna-contra-el-alzheimer-finaliza-la- phase-ii-trials-of-abvac40.html)

o The Danish A.P. Moller Holding completes the purchase of Unilabs (https://www.plantadoce.com/empresa/la-danesa-ap-moller-holding-completa-la-compra-de-unilabs.html)

o The founders of Rovi sell 5% after the success of the Moderna vaccine (https://www.europapress.es/economia/noticia-fundadores-laboratorios-rovi-venden-capital-empresa-1808-millones-20220315082314.html )

o Hipra hopes to market its covid vaccine in June (https://www.businessinsider.es/vacuna-hipra-covid-comercializar-junio-primera-espanola-1029741)