7 days in healthcare (April 18-24, 2022)

Summary

From the point of view of biomedicine, to highlight the new devices that read the brain (brain-reading-devices) and allow movement, touch and speech to be recovered. Also the great future of liquid biopsy in the early diagnosis of cancer.

As far as Global Health is concerned, there is no choice but to quote Bill Gates’ new TED video discussing how to avoid a new pandemic, which follows his previously celebrated video from 2015, five years before COVID-19. . Also the devastating effects of covid on the evolution of tuberculosis. It is highly worrying that in Africa there is a large backlog of vaccines, after multiple donations, which speaks of serious logistical problems. More than 100 confirmed cases in a dozen countries of the new acute childhood hepatitis of unknown origin.

Regarding international health policy, it should be noted that, according to the WHO, the incidence and mortality of COVID is falling globally. The United States will host the second global conference on COVID on May 12, 2022. Serious problems continue to arise in China, particularly in Shanghai, where respect for the most minimal freedoms collides with certain public health measures that are intended to be imposed. The new outbreak of covid in Beijing highlights the difficulty of following the “zero-covid” policy without many deaths, due to the low percentage of vaccination among the elderly in China and the less efficacy of the Chinese Sinovac vaccine, compared to that of Pfizer-Biontech.

If we talk about national health policy (Spain), although the incidence of COVID continues to grow, the mandatory use of the mask indoors has been abolished, which for some is premature. From the regulatory point of view, the Health Advertising Law and the Pharmacy Law of the Community of Madrid are announced, both with controversial components. The CNI warns of the large number of cyberattacks in health so far in 2022. The “Vanguard Health” Alliance is created to coordinate the health PERTE. Great media impact of the publication “Private healthcare, adding value” by the IDIS Foundation.

In the field of companies, from the international point of view, it is worth noting the movements of KKR to buy the largest hospital company in Australia (Ramsay). In our country, the position of the AESEG on the need to establish differential prices between generics and brands is important. Also the five-year agreement between the Junta de Andalucía and the Pascual Hospital Group.

Biomedicine

Global health

News international health policy

  • COVID-19

o According to the WHO, both the number of cases and mortality fell in the last week, following a decline from the end of March (https://www.theguardian.com/world/2022/apr/21/new-covid- cases-globally-down-by-nearly-a-quarter-last-week)

o The United States will host the second global summit on COVID. It will be online on May 12, 2022 (https://www.consalud.es/politica/eeuu-cumbre-mundial-pandemia-covid-19_113280_102.html)

o Shanghai wants to open factories with employees living in them (https://www.lavanguardia.com/internacional/20220418/8203602/shanghai-covid-china-pandemia-empresas-impacto.html)

o New COVID outbreak in Beijing. The Chinese authorities do not want the situation in Shanghai to be reproduced (https://elpais.com/sociedad/2022-04-24/pekin-toma-medidas-de-contencion-tras-detectar-un-subito-aumento-de -cases-of-covid.html)

  • Other themes

o The questioning of the authorization of abortion in the USA (Roe v Wade ruling), can cause serious health problems. It can increase the mortality of women in relation to pregnancy by 21% and 33% in black women (https://www.bmj.com/content/377/bmj.o1019). Many media worldwide denounce the toxicity of these restrictive laws (https://www.ft.com/content/a2b0d282-9baa-40ed-9a2c-64bbeaa5e375)

o New incentives are needed to fight antibiotic resistance, a pioneering subscription system in the UK can help improve the situation (https://www.ft.com/content/954d5e13-884e-4090-afca- 378993510558)

o Europe will not approve Biogen’s aducanumab for Alzheimer’s for now, approved in the USA by the FDA, amid great controversy (https://www.diariomedico.com/farmacia/industria/empresas/europa-no-aprobara-por-ahora- aducanumab-for-alzheimer.html)

News national health policy (Spain)

  • COVID

o The incidence of COVID continues to rise: 555.47 cases on Friday, April 22, in people over 60 years of age per 100,000 in the last 14 days, compared to 505.86 on Tuesday, April 19 (https://www.elconfidencial .com/espana/2022-04-22/espana-suma-49-143-cases-and-187-deaths-and-the-incidence-in-over-60s-up-50-points_3412937/)

o After 700 days, the Council of Ministers approves the no obligation to wear a mask indoors, with some exceptions (https://www.elmundo.es/ciencia-y-salud/salud/2022/04/19/625e955c21efa04b4d8b45d0.html)

o The majority of Spaniards believe that it is soon to remove the mask indoors (https://elpais.com/sociedad/2022-04-20/la-mayoria-de-los-espanoles-cree-que-es-pronto -to-remove-the-masks-indoors-and-continue-wearing-it.html)

o The XE variant of covid is already beginning to circulate in Spain (https://www.abc.es/sociedad/abci-variante-coronavirus-empuerta-circular-espana-202204202033_noticia.html)

o Great controversy over the distribution of antivirals (https://www.larazon.es/sociedad/20220421/yda2ugjo3rcszl56bzcp75rvvm.html)

  • Regulatory announcements

o The health advertising law, presented by the PP, to be examined in Congress. It is promoted by the Council of Dentists and also by the OMC (Doctors Order) (https://www.consalud.es/politica/parlamentos/ley-publicidad-sanitaria-pp-examen-congreso-semana_113468_102.html)

o Madrid approves the Pharmacy Law, among the novelties, it develops home distribution (closing the door to the delivery of medicines from entities outside pharmacies) and makes schedules more flexible (https://www.diariomedico.com/farmacia/politica/ madrid-approves-the-new-pharmacy-law-in-its-government-council.html). The Spanish Society of Hospital Pharmacy opposes this bill, for not contemplating hospital pharmacy in the regulations (https://www.diariofarma.com/2022/04/22/la-sefh-rechaza-la-loaf- Madrid)

  • Other themes

o Public healthcare spending skyrockets in 2020 due to the pandemic (https://www.plantadoce.com/entorno/el-sns-pisa-el-acelerador-tras-la-pandemia-y-dispara-el-gasto-sanitario -up-to-83811-million-euros.html)

o CNI alert: large number of cyberattacks in healthcare in 2022 (https://www.elespanol.com/invertia/observatorios/sanidad/20220422/alerta-cni-sanidad-publica-espanola-ciberataques-peligrosidad/666683412_0.html)

o The Fundación Instituto Roche addresses the involvement of the microbiome in maintaining health (https://www.actasanitaria.com/tecnologia/fundacion-instituto-roche-aborda-implicacion-microbioma_2002274_102.html). To access the full document: https://www.institutoroche.es/recursos/publicaciones/202/Hablando_sobre_microbioma

o The Ministry of Health reports eight cases of severe childhood hepatitis of unknown origin (https://www.eldiario.es/sociedad/sanidad-notifica-ocho-casos-hepatitis-aguda-infantil-origen-desconocido_1_8935838.html)

o The investigations for the purchase of masks already exceed ten (https://www.elperiodico.com/es/politica/20220423/investigaciones-contratos-mascarillas-covid-superan-decena-13553701)

o The “Salud de Vanguardia” Alliance is born to coordinate the health PERTE (https://www.diariofarma.com/2022/04/20/nace-la-alianza-salud-de-vanguardia-para-coordinar-el-perte -sanitary)

o Great impact of the document “Private healthcare, adding value” from the IDIS Foundation: https://www.fundacionidis.com/uploads/informes/informe_sanidad_privada_aportando_valor_2022.pdf.

Companies

  • International News

o The private equity firm KKR launches an offer for the largest Australian private hospital group, Ramsay (https://www.ft.com/content/ee5553e3-5d5c-4fbb-af4b-72dd9be0ef0a)

o GBL (Group Bruxelles Lambert) acquires the diagnostic imaging company Affidea, which at the time had acquired some assets in Spain (Q Diagnóstica) (https://www.plantadoce.com/empresa/gbl-adquiere-la-compania -of-medical-diagnostic-services-affidea.html)

o GSK, Sanofi and J&J accelerate spin offs in the pharmaceutical business (https://www.expansion.com/empresas/2022/04/19/625de599e5fdea36148b4677.html)

  • National News

o Generics: AESEG rejects the current plan for generics and biosimilars (made public, but not yet implemented due to the pandemic) if there is no price differential with brands (https://www.redaccionmedica.com/secciones/industria/el -generic-reformulates-the-national-plan-with-the-price-difference-as-axis-1032)

o The Junta de Andalucía signs a five-year agreement with the Pascual hospitals for an amount of 771 million euros (https://sevilla.abc.es/andalucia/sevi-junta-andalucia-firma-contrato-clinicas-pascual-cinco -hospitals-until-2027-771-millions-202203291523_noticia.html)

o DKV skyrockets its profits, largely due to the extraordinary results of the sale of its stake in the Denia hospital, acquired by Ribera (https://cincodias.elpais.com/cincodias/2022/04/20/companias/1650456633_959356 .html)

o Sacyr will build a pediatric center in Canada for more than 60 million euros (https://www.plantadoce.com/empresa/sacyr-construira-un-centro-pediatrico-en-canada-por-mas-de-60- million-euros.html)

o Atrys Health sprints on the Stock Market and targets revenues of 200 million in 2022 (https://www.plantadoce.com/empresa/atrys-health-sprints-on-the-continuo-y-apunta-a-incomes- of-220-million-euros-in-2022.html)

 

 

7 days in healthcare (April 11-17, 2022)

 

 

SUMMARY

From the point of view of biomedicine, it is important to highlight the fact that greater access to antibiotics (reduced in many countries) is a basic element to overcome the pandemic of resistance to these drugs. Cases of acute hepatitis in children, detected in the United Kingdom and also in Spain, have been the subject of an alert by the WHO and the ECDC. Some of them require liver transplantation.

With regard to Global Health, the financing of the WHO is one of the great issues of global health, since this organization has always had a financing well below its challenges.

As for international health policy, President Biden’s Memorandum on “long covid” should be noted. Also the important article published in The Lancet that analyzes the circumstances surrounding the incidence of covid and its mortality in 177 countries, with some interesting conclusions. The “zero-covid” policy in China and, specifically, the confinement of Shanghai, continues to occupy the international front pages and is a policy that is beginning to be highly questioned, despite its successes so far in both the number of cases and in mortality, as in economic impact, if we believe the official figures from China. Great expectations regarding the new agency created by the Biden Administration: the ARPS-H (Advanced Research Projects Agency for Health)

If we talk about national health policy (Spain), 50,000 doses of covid have finally been distributed, albeit with great delay compared to the initial promises, although without having agreed on criteria regarding their use. Interesting proposal to the Ministry of Health of the Medical Collegiate Organization (OMC) on medical recertification, which includes a supervisory agency OMC-FACME, similar to a British one.

In the field of companies, from the international point of view, to highlight the declines in sales of covid vaccines. Regarding national news, the announcement of the forthcoming arrival of the HIPRA vaccine should be highlighted.

 BIOMEDICINE

GLOBAL HEALTH

INTERNATIONAL HEALTH POLICY

  • COVID

o President Biden’s memorandum on addressing the “long COVID” (https://www.whitehouse.gov/briefing-room/presidential-actions/2022/04/05/memorandum-on-addressing-the-long-term- effects-of-covid-19/). Article on the subject in JAMA magazine: https://jamanetwork.com/journals/jama-health-forum/fullarticle/2791210

o Preparedness for the pandemic and covid, an analysis of 177 countries. The relationship between various circumstances and the incidence of covid, as well as mortality, are analyzed (https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)00172-6/fulltext). Comments on this article, the WHO and health systems remain unprepared to deal with a pandemic like covid, which caused 494 million cases and more than 6 million deaths, as of April 5, 2022: https://www. thelancet.com/journals/lancet/article/PIIS0140-6736(22)00425-1/fulltext

o Shanghai lockdown shows signs of desperation among the population and lack of food (https://www.theguardian.com/world/2022/apr/17/shanghai-lockdown-desperation-rises-food-runs-low-china )

o The mystery of China with “ómicron”: 280,000 infections and zero deaths (https://www.abc.es/sociedad/abci-misterio-china-omicron-280000-contagios-y-cero-muertes-202204150122_noticia.html)

o The WHO confirms a decrease in new covid cases worldwide, for the third consecutive week (https://www.diariofarma.com/2022/04/13/la-oms-confirma-la-disminucion-de-nuevos -covid-cases-around-the-world)

o Covid infections start to fall in the UK (https://www.ft.com/content/0c2fc3ce-be3f-41b1-8b1f-e1b729882720)

o Valneva, the Franco-Austrian vaccine against covid, is the sixth approved in the United Kingdom (https://www.theguardian.com/world/2022/apr/14/valneva-approved-to-be-uks-sixth -covid-vaccine)

o The FDA authorizes the first breath-based covid test that produces results in less than three minutes (https://www.nytimes.com/2022/04/15/us/the-fda-authorizes-the- first-covid-19-breath-test.html)

  • Other themes

o Expectations about the new health agency created by Biden, called ARPA-H (Advanced Research Projects Agency for Health). Editorial in Science magazine (https://www.science.org/doi/10.1126/science.abq4814)

o The number of people on the NHS waiting list at record high (https://www.theguardian.com/society/2022/apr/14/number-of-people-on-nhs-waiting-lists-in-england -at-record-high)

o The number of primary care physicians (GPs) in the UK, down every year since 2015. Organizations representing doctors say the heavy workload, high expectations of patients, difficulties recruiting non-medical staff and the fear of errors due to overload, at the base of this situation (https://www.theguardian.com/society/2022/apr/11/gp-numbers-in-england-down-every-year-since-2015 -pledge-to-raise-them)

o A lawsuit by Cuban doctors has been accepted by the US justice system, accusing the PAHO (WHO organization for Latin America) of collaborating in the “forced labor” of Cuban doctors sent to Brazil (https://www. .bmj.com/content/377/bmj.o962)

NATIONAL HEALTH POLICY (SPAIN)

  • COVID

o Spain, the rich country where life expectancy fell the most due to the pandemic, after the United States (https://www.elespanol.com/ciencia/salud/20220414/espana-pais-rico-cayo-esperanza-pandemia-unidos /664683895_0.html)

o The covid increased health spending in 2020 by 10.9%, a record figure (https://www.diariofarma.com/2022/04/06/la-covid-incremento-el-gasto-sanitario-en-2020 -a-109-a-figure-record)

o The Ministry of Health has already distributed 50,000 doses of Paxlovid in Spain (https://www.consalud.es/politica/ministerio-sanidad/sanidad-distribuido-espana-50000-dosis-farmaco-covid-19-paxlovid_113219_102.html)

  • Other themes

o Three cases of childhood hepatitis of unknown origin detected in Spain, following an international alert from the WHO and the ECDC, originating in the United Kingdom (https://elpais.com/sociedad/2022-04-13/detectado- in-spain-the-first-case-of-an-infantile-hepatitis-of-unknown-origin.html)

o Spain, at the tail of the large European markets in access to cancer and orphan drugs (https://www.diariomedico.com/medicina/medicina-preventiva/politica/espana-la-cola-de-los-grandes-mercados -europeans-in-access-oncology-drugs-and-orphans.html)

o The Government wants to reduce tobacco consumption, without prohibiting smoking (https://elpais.com/sociedad/2022-04-10/espana-quiere-desatascar-la-caida-de-fumadores-sin-recurr-a-la- prohibition.html)

o The Collegiate Medical Organization (OMC) makes a proposal to the Ministry of Health on medical recertification according to the English model with three measures. It proposes that the OMC-FACME could be the supervisory agency, similar to the “Professionals Standards Authority for Health and Social Care”, of the United Kingdom (https://www.redaccionmedica.com/secciones/medicina/- English-model-of -medical-recertification-with-3-measures-of-competence-6828)

o The Spanish transplant model triumphs in Latin America, where organ donation grew by 100% between 2005 and 2019 (https://www.consalud.es/politica/donacion-organos-iberoamerica-programa-espanol_112999_102.html)

o Harassment of women who go to abortion clinics is declared a crime, through a modification of the Penal Code (https://www.consalud.es/pacientes/acoso-mujeres-acudan-clinicas-abortar-delito-jueves_113177_102. html)

o Family Medicine, Anesthesiology, Psychiatry and Radiodiagnosis, among the specialties that will have to increase their MIR offer to alleviate the deficit, according to a recent report (https://www.diariomedico.com/medicina/profesion/espana-pagara-en -five-years-the-lack-of-planning-in-medical-templates.html)

COMPANIES, EMPLOYERS AND OTHER AGENTS IN THE SECTOR

  • International News

o Walgreens, the American pharmacy chain, flooded the market with opiates and is accused of creating addicts (https://www.consalud.es/ecsalud/internacional/walgreens-farmaceutica-opiaceos-mercado-crear-adictos_113123_102.html)

o GSK, about to buy Sierra Oncology for 1,500 million pounds to boost its oncology offer (https://www.ft.com/content/d26ea24f-1ea9-4b09-842d-4708090bfe42)

o The vaccine business drops, with a 21% drop in sales (https://www.elespanol.com/invertia/observatorios/sanidad/20220412/business-vacunas-anticovid-cae-prevision-ventas-demanda/ 664183929_0.html)

  • National News

o Farmaindustria pays 452 million to the State for excess public spending on medicines in 2018 and 2019 (https://www.elespanol.com/invertia/observatorios/sanidad/20220411/farmaindustria-abona-millones-exceso-gasto-publico- medications/663433943_0.html)

o The HIPRA vaccine will arrive between May and June, according to Minister Morant (https://www.elespanol.com/ciencia/salud/20220411/vacuna-espanola-hipra-covid-llegara-ministra-morant/664183699_0.html)

o Boehringer Ingelheim reinforces its commitment to Spain with an investment in R&D of 42 million in 2021, 23% more than in the previous period (https://www.plantadoce.com/empresa/boehringer-ingelheim-refuerza-su -bet-on-spain-with-an-investment-of-42-million-in-2021.html)

o Lácer launches its sale process for more than 500 million euros (https://cincodias.elpais.com/cincodias/2022/04/08/companias/1649439648_227115.html)

o Insparya, the hair business that Cristiano Ronaldo is in, will take its clinics to Milan, Paris and Dubai and will continue to open in Spain (https://cincodias.elpais.com/cincodias/2022/04/08/companias/1649440871_986204. html)

 

 

7 days in healthcare (April 4-10, 2022)

 

SUMMARY

From the point of view of biomedicine, it is worth highlighting the fact, highlighted by the journal Nature, that the WHO took more than two years to recognize the airborne transmission of covid. A new generation of vaccines that prevent cancer can make tumors disappear before they appear, according to an article in Science. The natural experiment from South Korea and Hong Kong shows that the “omicron” variant can be fatal in unvaccinated people.

As far as Global Health is concerned, the situation in Ukraine gives us difficult lessons in global health, explains the editor of The Lancet. It should be noted that the black American population already exceeds the white population in mortality from opioids. Until now, deaths from this cause occurred mainly in “non-colleged educated” whites.

Regarding international health policy, the European health agencies (EMA and ECDC) say that it is too early for the second “booster” of the covid vaccine. Ten years of “Choosing Wisely” the revolution in medical practice that tries to minimize worthless or low value health interventions.

If we talk about national health policy (Spain), the appearance of the 2022 Health Barometer (First wave) is important. It should be noted that waiting lists are the main concern of the population; the delay in a high percentage of cases to see a primary care physician; and that the positive perception of the public system decreases, while that of the private system increases. Report on health professionals, which says that within five years there will be a shortage of 9,000 doctors.

In the field of companies, from the international point of view, Moderna’s agreement with the non-profit entity IAVI to apply mRNA technology to various diseases should be highlighted. SpainCares confirms that Spain is not in an advantageous position with regard to health tourism.

BIOMEDICINE

GLOBAL HEALTH

INTERNATIONAL HEALTH POLICY

  • COVID

o The United States donates more than 100 million doses of covid vaccine for children (https://www.ft.com/content/3e5f9359-67a5-4f24-971e-51761119899b)

o Shanghai residents beg for food and medicine as authorities lock down the city (https://www.ft.com/content/3e439a10-860b-4ae6-9070-ad8546da8850)

o Olaf Scholz, German Chancellor, fails in Parliament with his plan to make the vaccine mandatory (https://www.ft.com/content/7d0610bf-3cf9-4edd-a392-e9d97dc9fade)

o COVID deaths rise in the UK, with infections at record highs (https://www.theguardian.com/world/2022/apr/05/covid-related-deaths-rise-england-infections-record-high )

o The European health agencies (EMA and ECDC) say that it is too early for the second covid vaccine “booster” (https://www.nytimes.com/2022/04/06/world/europe/covid-second- booster-europe.html)

  • Other themes

o Ten years of “Choosing Wisely”, which revolutionized medical practice based on recommendations of “do not do”, to reduce low-value health care (https://www.nejm.org/doi/full/10.1056/ NEJMp2200422)

o Life expectancy in the US continues to decline in 2021, despite covid vaccines (https://www.washingtonpost.com/health/2022/04/07/life-expectancy-covid/)

o Oklahoma passes one of the toughest anti-abortion laws in the US, following a Republican strategy (https://www.ft.com/content/cee6a170-fa23-47cb-b554-d457d68f225b)

o Important report by the Nuffield Trust on the recovery of health systems after covid, analyzing the situation in several countries (https://www.nuffieldtrust.org.uk/research/health-system-recovery-from-covid-19- international-lessons-for-the-nhs)

o Great impact in the United Kingdom of the Ockenden Report, on maternity care, with the detection of serious problems, published by the British Government (https://www.gov.uk/government/publications/final-report-of- the-ockenden-review/ockenden-review-summary-of-findings-conclusions-and-essential-actions)

NATIONAL HEALTH POLICY (SPAIN)

  • COVID

o Decrease in the incidence of covid: up to 420.17 cases per 100,000 inhabitants over 60 years of age, according to the new measurement method (https://www.redaccionmedica.com/directo/coronavirus-ultimas-noticias/20220410)

o The mask will no longer be mandatory indoors on April 20 (https://www.elmundo.es/ciencia-y-salud/salud/2022/04/06/624d770121efa0ed708b45bb.html)

o COVID only worries 30% of Spaniards, according to the COSMO Spain study, coordinated by the Carlos III Health Institute (https://www.actasanitaria.com/salud-mental/covid-19-solo-pretrabajo-30 -spanish-two-years-pandemic_2002232_102.html)

  • Other themes

o The 2022 Health Barometer (First wave) appears (https://datos.cis.es/pdf/Es3357mar_A.pdf). Some data of interest: the waiting lists, the worst valued by the Spanish (https://www.lavanguardia.com/vida/20220407/8184215/listas-espera-peor-valorado-espanoles-barometro-sanitario-2022.html ); 55% of patients take more than 7 days to get an appointment with their family doctor (https://www.lavanguardia.com/vida/20220408/8185940/55-pacientes-tarda-mas-7-dias-conseguir- family-doctor-appointment.html); lowers the positive perception of the public system and increases that of the private (https://www.diariofarma.com/2022/04/07/cis-baja-la-percepcion-positiva-del-sistema-publico-y-aumenta-la-de-la-privada)

o Within five years there will be a shortage of almost 9,000 doctors (https://www.lavanguardia.com/vida/20220404/8174200/cinco-anos-faltaran-9000-medicos.html), according to the report “Supply-need for medical specialists 2021- 2035”, prepared by Patricia Barber and Beatriz González López-Valcárcel (https://cgcom.es/sites/default/files//u395/2022informeofertanecesidadespecialistasmedicos2021_2035.pdf)

o “Case of masks” a loot of 2,000 million for the purchase of material during the state of alarm (https://elpais.com/espana/2022-04-10/caso-mascarillas-un-botin-de-2000-millones -in-the-law-of-the-jungle.html)

o WAIT Report: Spain falls in time for access to new medicines (https://www.diariofarma.com/2022/04/06/espana-ha-autorizado-el-53-de-los-farmacos-aprobados -in-europe-between-2017-y-2020), to see the WAIT report: https://www.efpia.eu/media/602652/efpia-patient-wait-indicator-final-250521.pdf

o Published the “Report on the initial budgets of the Public Administrations” (AIREF, April 7, 2022) (https://www.airef.es/wp-content/uploads/2021/04/PRESUPUESTOS-INICIALES/Informe-Ptos -initials-2021-.pdf)

o Spain leads the world consumption of benzodiazepines (https://www.elperiodico.com/es/sociedad/20220402/espana-lidera-consumo-mundial-benzodiazepinas-13438583)

COMPANIES, EMPLOYERS AND OTHER AGENTS IN THE SECTOR

  • International News

o Moderna reaches an agreement with IAVI (non-profit association) to apply mRNA to various diseases (https://www.plantadoce.com/empresa/moderna-llega-a-un-acuerdo-con-iavi-para-aplicar -mRNA-for-various-diseases.html)

o Pfizer buys the British biotech company ReViral for 481 million euros (https://www.expansion.com/empresas/industria/2022/04/08/624fd580468aebc31f8b46bb.html)

  • National News

o David Medina (Spaincares): “In the tourism-health binomial, we are not in the top ranking” (https://www.plantadoce.com/adn/david-medina-spaincares-en-el-binomio-turismo-salud -we-are-not-at-the-top-of-the-ranking.html)

o Savana closes a round of 23 million euros, hand in hand with Conexo Ventures (https://www.plantadoce.com/empresa/savana-cierra-una-ronda-de-23-millones-de-euros-de- the-hand-of-connected-ventures.html)

o Sanitas shoots up sales of health insurance by 47%, with 377,000 new policies (https://cincodias.elpais.com/cincodias/2022/04/07/companias/1649322015_528839.html)

o PharmaMar and CNIO allocate 1.2 million euros to testing breast cancer drugs (https://www.plantadoce.com/empresa/pharma-mar-y-el-cnio-destinan-12-millones-de- euros-to-test-drugs-against-breast-cancer.html)

o Miranza underpins its expansion, reaching 80.6 million euros (https://www.plantadoce.com/empresa/miranza-apuntala-su-expansion-tras-incrementar-sus-ventas-un-35-hasta-806 -millions-of-euros.html)

o Farmasierra celebrates its 25th anniversary, reinforcing R&D (https://www.diariomedico.com/farmacia/industria/empresas/farmasierra-celebra-su-25-aniversario-advancing-towards-a-model-industria-40. html)

o Pfizer will export gene therapies from Spain to America (https://www.eleconomista.es/salud/noticias/11706685/04/22/Pfizer-exportara-a-America-terapias-genicas-desde-Espana.html)

 

7 days in healthcare (March 21-27, 2022)

 

SUMMARY

From the point of view of biomedicine, the progress in the treatment of breast cancer should be highlighted, according to the article published by the NEJM, with a brake of around 80% of this advanced cancer and makes it disappear in 16%. .

As far as Global Health is concerned, there are undiagnosed cases of tuberculosis (the missing tuberculosis), a disease that continues to have 10 million new cases a year and causes 1.5 million deaths. The Lancet report on what needs to be done to meet target 3.4 of (on non-communicable diseases) of the Sustainable Development Goals. Inequality in covid vaccination and its possible ways to solve it are the subject of an analysis by the NEJM. Concern for the health of the 3.5 million refugees from Ukraine. The low mortality of covid in Africa, a continent that was thought could be devastated by this disease, remains a mystery.

As for international health policy, the debate continues on the covid-zero policy in China, which has achieved great results so far (both in terms of mortality and economics), but it is not known if it will be able to continue with the variant “omicron”. The WHO judges the lifting of COVID measures in Europe too premature, considering that cases are growing, among other countries, in the United Kingdom, Ireland, Greece, France, Italy and Germany.

If we talk about national health policy (Spain), we are witnessing a relaxation of the measures against covid, despite its upward trend in recent days. Arrival of Paxlovid, Pfizer’s treatment for severe cases of covid. The important report published by the Catalan Society of Health Management, with an exceptional team led by Jordi Varela, on the forms of contracting health services from the point of view of value, is very noteworthy. The deans of Medicine react to the Ministry’s announcement of the increase in the “numerus clausus” in medicine by 10%.

In the field of companies, it is worth highlighting the evolution of the purchase of the fertility company IVI, the largest operation carried out by private equity companies in healthcare in Spain and with a company valuation of around 2,500 million euros.

BIOMEDICINE

GLOBAL HEALTH

INTERNATIONAL HEALTH POLICY

NATIONAL HEALTH POLICY (SPAIN)

COMPANIES, EMPLOYERS AND OTHER AGENTS IN THE SECTOR

 

 

7 days in healthcare (March 14-20, 2022)

 

SUMMARY

From the point of view of biomedicine, to highlight the new treatment for malaria in children; the new variant “Delatacron”, similar to the “ómicron”; and, the possibilities of artificial intelligence to accelerate the appearance of new medicines. We would like to underline the studies promoted by Valentín Fuster on ultrasound of the neck and groin arteries and their possibilities of detecting the risk of myocardial infarction and stroke to be promising, although it is a topic that has been talked about for a long time without much results.

Regarding Global Health, an interesting editorial in the British Medical Journal, entitled climate change, pandemic and war: an uncontrolled multi-crisis, since it seems that in this decade of the 21st century all the problems have accumulated; the verification that the low level of vaccinations in Africa is not so much due to the low level of vaccines, but rather due to the difficulties of reaching the population; interesting report on Nigeria and the problems of its health system.

In terms of international health policy, the problems of Asia’s “covid zero” strategy are noteworthy, which gave so much political return to the Chinese regime, presenting its low mortality successes and comparing them with the high mortality rates of other countries in the world ( United States, Brazil, United Kingdom, India, etc.). It seems that the “ómicron” variant, due to its contagiousness, is not easily approachable with the “covid zero” strategy, since that would lead to massive confinements in China. Resurgence of covid cases in Europe and Asia, which coincides with a relaxation of control measures.

If we talk about national health policy (Spain), it should be noted that the incidence of covid is growing, while the measures are relaxed, although there is concern in the Ministry of Health about a possible new wave of covid at the gates of Easter. Very important COFARES report on the pharmacy sector, proposing many innovative measures, which contrasts with the usual narcissism and laudatory speeches about the “Mediterranean model of pharmacy”, so liked by some professional representatives. Primary Care is trying to get back to normal, although with a thousand fewer doctors than before the pandemic. The birth rate in Spain is at historic lows, which is a serious problem. The Council of Dentists, in reporting that 34 million Spaniards have cavities, presents us with the reality of poor dental care in our country. A revolution in the use of biosimilars is coming, given the large number of biological medicines that will lose their patent in the coming years.

In the field of companies, it should be noted that Pfizer and BioNTech have requested authorization in the United States for a second “booster” for older Americans. Grifols bets on a vaccine against Alzheimer’s. HIPRA, the veterinary pharmacy company until now, hopes to start marketing its vaccine against covid in June.

BIOMEDICINE

GLOBAL HEALTH

INTERNATIONAL HEALTH POLICY

  • COVID

o The “ómicron” variant is changing China’s “zero covid” strategy, at the moment more than 40 million Chinese are suffering some type of confinement, which is tolerated by the remaining 1.4 billion who lead normal lives. The legitimacy of the party is given by the low mortality. We’ll see if that can be sustained with the “omicron” (https://www.economist.com/china/2022/03/19/omicron-is-changing-chinas-covid-strategy)

o China reports the first deaths from covid in more than a year (https://www.nytimes.com/live/2022/03/18/world/covid-19-mandates-cases-vaccine)

o Shanghai, possible confinement, after the discovery of 150 new cases of covid (https://www.ft.com/content/659a5337-681b-4ef2-a9ac-db9aaaa78cef)

o Concern that new lockdowns in China may disrupt supply chains (https://www.economist.com/finance-and-economics/will-chinas-covid-lockdowns-add-to-strains-on-supply- chains/21808193)

o Resurgence of covid cases in Europe and Asia, infections have risen 8% worldwide, but they are skyrocketing in Vietnam and Germany (https://www.larazon.es/sociedad/20220317/z4bkdrxn2vddtcbvhi5equn45e.html)

  • Other issues

o According to an American study (Health Affairs), hospitals differ in their services depending on whether they are for-profit, non-profit or government-owned, with the former tending to offer more profitable services and discontinue the others (https://www.healthaffairs. org/doi/epdf/10.1377/hlthaff.2021.01115)

NATIONAL HEALTH POLICY (SPAIN)

  • COVID

o Latest report: the incidence of covid rise and 287 deaths, in Friday’s report (since Tuesday) (https://www.consalud.es/pacientes/especial-coronavirus/covid-19-espana-registra-64597 -cases-287-deaths-ia-upload-44580-points_111800_102.html)

o The new plan against covid will put an end to the isolation of positives (https://www.lavanguardia.com/vida/20220319/8136758/nuevo-plan-covid-pondra-aislamientos-positivos.html)

o The Ministry of Health fears the arrival of a new wave of covid at the gates of Holy Week (https://www.elespanol.com/espana/20220314/sanidad-llegada-septima-covid-puertas-semana-santa/656934435_0 .html)

o Paxlovid, the anticovid treatment promised by Sánchez, has not yet reached patients (https://www.elmundo.es/ciencia-y-salud/salud/2022/03/17/623244e021efa054348b458d.html)

  • Other themes

o Spain was left out of the top 10 in public health spending in 2020, according to a report made public by Eurostat and spent an average of 600 euros less per inhabitant than the EU average (https://www.consalud.es/politica/espana- top-10-ue-public-expenditure-health-2020_111467_102.html). To access the Eurostat report: https://ec.europa.eu/eurostat/databrowser/view/GOV_10A_EXP__custom_2243551/bookmark/table?lang=en&bookmarkId=8df11907-86e8-4f5b-a62e-a7d09828e303)

o Important COFARES report: pharmacist skills in the 21st century, proposing digitization, home delivery, legal changes and the sustainability of the pharmacy model (https://www.consalud.es/profesionales/profesionales-analizan- evolution-pharmacy-role-pharmacist_111660_102.html)

o The Ministry of Health and the regions coordinate health care for refugees from Ukraine (https://www.diariofarma.com/2022/03/18/sanidad-y-las-cc-aa-garantizan-la-atencion- health-for-refugees-from-ukraine)

o The Ministry of Health puts the average time to approve a drug at “9 months” (https://www.consalud.es/politica/ministerio-sanidad/sanidad-asegura-la-media-espana-aprobar-medicamento-9- months_111648_102.html)

o The flu enters Spain with force (https://www.lavanguardia.com/vida/20220317/8130742/gripe-fuerza-espana.html)

o Primary Care is trying to get back to normal, with a thousand fewer doctors than before the pandemic (https://elpais.com/sociedad/2022-03-20/la-atencion-primaria-intenta-volver-a-la- normality-with-a-thousand-less-doctors-than-before-the-pandemic.html)

o The birth rate in Spain, at lows not known in several centuries, according to a study by the San Pablo CEU University (https://www.eldebate.com/sociedad/20220315/pandemia-apenas-pasa-factura-natalidad-espana. html)

o A total of 34 million people in Spain have cavities, according to the General Council of Dentists (https://www.actasanitaria.com/politica-y-sociedad/total-34-millones-personas-en-espana-tienen- caries_2001822_102.html)

o The Ombudsman receives 2,300 health complaints in 2021, according to the report presented (https://www.defensordelpueblo.es/informe-anual/informe-anual-2021/)

o La Paz, on October 12 and Gregorio Marañón among the 100 best hospitals in the world, according to the classification prepared by Newsweek magazine (https://www.elmundo.es/madrid/2022/03/14/622e4da7e4d4d894118b45c8.html )

o Incorporating 6,000 doctors in primary care would cost 358 million euros, according to the Collegiate Medical Organization (https://www.elmundo.es/ciencia-y-salud/salud/2022/03/14/622df5e7fc6c83c80d8b4583.html)

o Mariano Esteban’s covid vaccine will not continue the clinical phase in Spain (https://www.diariomedico.com/medicina/enfermedades-infecciosas/empresas/la-vacuna-de-la-covid-de-mariano-esteban -csic-will-not-continue-the-clinical-phase-in-spain.html)

o Spain needs a plan for the second revolution in biosimilars, since one hundred biological drug patents expire between 2024 and 2029 (https://cincodias.elpais.com/cincodias/2022/03/16/companias/1647452966_841014.html)

COMPANIES, EMPLOYERS AND OTHER AGENTS IN THE SECTOR

  • International News

o Moderna supplies 70 million additional doses of its vaccine to Japan (https://www.plantadoce.com/empresa/moderna-suministra-70-millones-de-dosis-addicionales-de-su-vacuna-anti-covid- 19-a-japan.html)

o Pfizer and BioNTech request authorization for a second “booster” for older Americans (https://www.nytimes.com/2022/03/15/us/politics/pfizer-second-booster-shot-older-americans.html )

o AstraZeneca, prepared not to continue with the efforts to obtain authorization in the USA for the covid vaccine (https://www.ft.com/content/e1edb2b2-0e12-4c83-9257-eeeb2ba29267)

  • National News

o Grifols bets on the Alzheimer’s vaccine and ends phase II of clinical trials (https://www.plantadoce.com/empresa/grifols-apuesta-por-la-vacuna-contra-el-alzheimer-finaliza-la- phase-ii-trials-of-abvac40.html)

o The Danish A.P. Moller Holding completes the purchase of Unilabs (https://www.plantadoce.com/empresa/la-danesa-ap-moller-holding-completa-la-compra-de-unilabs.html)

o The founders of Rovi sell 5% after the success of the Moderna vaccine (https://www.europapress.es/economia/noticia-fundadores-laboratorios-rovi-venden-capital-empresa-1808-millones-20220315082314.html )

o Hipra hopes to market its covid vaccine in June (https://www.businessinsider.es/vacuna-hipra-covid-comercializar-junio-primera-espanola-1029741)

 

 

7 days in healthcare (March 7-13, 2022)

 

SUMMARY

From the point of view of Biomedicine, the Lancet report on risk factors in COPD (chronic obstructive pulmonary disease), one of the great burdens of all health systems, should be highlighted. Also the finding that COVID can cause brain damage, although its scope is yet to be determined.

As for Global Health, it is worth noting the WHO complaint that 16 health facilities have been attacked in the war in Ukraine, as well as the organization’s statement that women should have access to safe abortions, to avoid mortality as well as hospitalizations due to complications.

When it comes to international health policy, the advice for the next pandemic contained in a major editorial in the Financial Times is important. There would be three priorities: 1. Reduce the risk of the appearance of a new pathogen (controlling the markets where animals are sold, for example); 2. Prevent it from spreading throughout the world; and 3. Develop an effective weaponry with vaccines and treatments as soon as possible. The incidence of COVID is increasing in England and France, just as the outbreak in China is the largest since the initial one in Wuhan. A report by The Lancet analyzes the mortality from COVID by country and even (as in the case of Spain) by region in the different countries. Spain is among the nations with the highest mortality from COVID per number of inhabitants. In the United Kingdom, a conservative think tank, with the support of the British Secretary of Health, proposes that primary care physicians become primarily salaried, thus breaking one of the fundamental elements of the political pact that gave rise to the NHS (on the one hand, hospitals are nationalized, but, on the other, the consideration of primary care physicians as independent mini-entrepreneurs is respected).

In national health policy, it is found that the drop in the incidence of COVID stagnates in Spain. Private healthcare, through the IDIS Foundation, considers the interoperability of the clinical history of private healthcare patients, regardless of insurer or provider.

Of the activity of the companies, an analysis of the Financial Times comments on how the economy of the pharmaceutical companies works against the development of antibiotics. Europe has lost the race against the United States in the development of new drugs. Important publication of the Roche Institute of a manual on personalized medicine aimed at health professionals.

BIOMEDICINE

GLOBAL HEALTH

INTERNATIONAL HEALTH POLICY

  • COVID

o Lessons for the next pandemic, after two years of covid, an important Financial Times editorial. Three priorities: 1. Reduce the risk of emergence of a new pathogen; 2. Prevent it from spreading throughout the world; and 3. Develop an effective weaponry with vaccines and treatments as soon as possible (https://www.ft.com/content/c9640c9c-5a65-49fa-a8b2-c22cc1ffe508)

o The COVID pandemic has lasted two years. Next steps may be divisive (https://www.nytimes.com/2022/03/12/us/covid-pandemic-vaccines-mandates.html)

o The covid does not decrease, but increases, in France (https://www.lemonde.fr/planete/article/2022/03/11/covid-19-olivier-veran-alerte-au-sujet-d-un -rebond-de-l-epidemie_6117120_3244.html)

o Covid cases and hospitalizations on the rise in England (https://www.theguardian.com/world/2022/mar/11/covid-cases-england-omicron-levels-ons-data)

o China, fighting the largest outbreak since Wuhan (https://www.ft.com/content/1e7dab0d-3247-4cb7-8370-e1697d70d693)

o Chinese scientists, in search of an alternative to the “zero COVID” policy, which the Chinese government boasts so much about (https://www.economist.com/china/2022/03/10/chinas-scientists-are-looking-for-a-way-out-of-the-zero-covid-policy)

o Where did the 5 “Trillion” (American) dollars of Covid stimulus go(https://www.nytimes.com/interactive/2022/03/11/us/how-covid-stimulus-money-was-spent.html)

o Mortality from COVID, three times higher than official figures (https://www.theguardian.com/world/2022/mar/10/global-covid-19-death-toll-may-be-three-times-higher-than-official-figures), according to a major report by The Lancet (http://www.thelancet-press.com/embargo/COVIDexcessmortality.pdf)

o Austria suspends the first universal vaccination obligation (https://www.ft.com/content/65650cbe-10b0-4350-8eb5-691624be8c2d)

  • Other topics

o The pandemic has accelerated the demand for private healthcare services in the UK (https://www.bmj.com/content/376/bmj.o566)

o The NHS app should be the new ‘gateway’ to the NHS, says UK health secretary (https://www.bmj.com/content/376/bmj.o621)

o British primary care physicians should be primarily salaried (https://www.bmj.com/content/376/bmj.o594), says a report by a conservative think tank (https://policyexchange.org.uk/publication/at-your-service/)

NATIONAL HEALTH POLICY (SPAIN)

  • COVID

o The drop in infections stagnates in Spain, with the incidence still at high risk, with 430.1 cases per 100,000 inhabitants, far from 50 (https://elpais.com/sociedad/2022-03-12/la-caida-de-contagios-de-covid-se-estanca-en-espana-con-la-incidencia-aun-en-riesgo-alto.html)

o Sánchez announces that the mandatory indoor mask will soon be abolished (https://www.rtve.es/noticias/20220306/sanchez-anuncia-pronto-se-supulsara-mascarilla-obligatoria-interiores/2303441.shtml)

o Spain destroys more than a million vaccines against covid, most of them from Janssen and AstraZeneca (https://www.elespanol.com/espana/politica/20220306/espana-destruye-vacunas-covid-19-mayoria-janssen-astrazeneca/654184713_0.html)

  • Political announcements

o Congress backs the proposal of the political party Ciudadanos for a law on ALS (https://www.larazon.es/sociedad/20220308/pvwdajf2yrgljceanzw4qgsr6a.html)

  • Other themes

o The Valencian health system carries out almost 600 sex change interventions in five years (https://www.eldiario.es/comunitat-valenciana/sanidad-valenciana-realiza-600-intervenciones-quirurgicas-cambio-sexo-cinco-anos_1_8822169.html)

o 9,932 candidates will be able to choose a MIR position (https://www.diariomedico.com/medicina/medico-joven/mir/9932-candidatos-podran-elegir-plaza-mir.html)

o The IDIS calls for more accessibility in Oncology (https://www.redaccionmedica.com/secciones/privada/el-idis-pide-un-modelo-de-organizacion-en-oncologia-accesible-y-equitativo-7382)

o Change in the General Directorate of Farmaindustria (https://cincodias.elpais.com/cincodias/2022/03/09/companias/1646826907_604545.html)

o The Royal National Academy of Medicine joins the European Academies of Medicine with a declaration on Ukraine (https://www.ranm.es/noticias/4799-declaracion-de-la-ranme-sobre-la-situacion-en-ucrania.html)

o Private healthcare invests 1.3 million euros to give private healthcare patients access to digital medical records in 2023 (https://www.elespanol.com/invertia/observatorios/sanidad/20220310/sanidad-privada-invierte-millones-pacientes-historia-clinica/656184536_0.html)

COMPANIES, EMPLOYERS AND OTHER AGENTS IN THE SECTOR

  • International News

o The Sacklers will pay $6 billion for Purdue’s opiate lawsuits (https://www.consalud.es/ecsalud/internacional/sacklers-pagaran-6000-millones-demandas-opiaceos-purdue_111017_102.html)

o Kirin goes beyond beer and goes into healthcare (https://www.ft.com/content/1d99a0be-6e76-4327-8516-da549a5f767e)

o How Pharmaceutical Economics Holds Back Antibiotic Development (https://www.ft.com/content/29292a3c-321d-4187-9ff0-59d70eb796f4)

o Europe loses the battle against the USA and only develops 22% of new medicines (https://cincodias.elpais.com/cincodias/2022/03/07/companias/1646677340_160102.html)

o Sanofi acknowledges that they were late for the covid vaccine (https://www.elmundo.es/ciencia-y-salud/salud/2022/03/13/6229d430fc6c832c328b4584.html)

  • National News

o Korian: 60 new beds and more purchases to bill one hundred million euros in Spain (https://www.plantadoce.com/empresa/korian-60-nuevas-camas-y-mas-compras-para-facturar-cien-millones-de-euros-en-espana.html)

o Europe asks HIPRA to expand its clinical trial of the covid vaccine (https://cincodias.elpais.com/cincodias/2022/03/07/companias/1646677340_160102.html)

o The Roche Institute publishes a personalized medicine manual for healthcare professionals (https://www.institutoroche.es/recursos/publicaciones/201/Propuesta_de_competencias_en_Medicina_Personalizada_de_Precision_de_los_profesionales_sanitarios)

 

 

 

7 days in healthcare (February 28-Mars 6, 2022)

 

SUMMARY

From the point of view of biomedicine, the approach (apparently possible) of obtaining a vaccine for the next pandemic in 100 days stands out, compared to 10 years of previous situations and the year of COVID 19. Concern, according to an editorial in The Lancet, for depression, which is estimated to affect one billion people in the world. The WHO warns about the high figures of obesity: 650 million adults, 340 million adolescents and 39 million children. Great hopes in the combination of gene therapy and xenotransplantation, with great impact on the future of transplants.

Regarding global health, the great concern is the health consequences of the war in Ukraine and the WHO calls for the creation of a safe corridor to carry medical supplies. Pharmaceutical companies plan to manufacture 2.9 billion COVID vaccines in Africa.

Regarding international health policy, it should be noted that, according to experts, billions of dollars are needed to prevent the next pandemic.

As far as national health policy is concerned, it should be noted that the incidence of COVID is falling, although more slowly than a few weeks ago, and the mortality rate remains high (more than 150 deaths per day). The (official) deaths from COVID already exceed 100,000 in Spain. The Ministry plans to give the COVID data twice a week, instead of the current daily frequency (except weekends). Great collaboration in medical supplies and supply of beds by Spain in the face of the tragedy in Ukraine.

If we talk about companies, we would highlight the information from FENIN that Catalonia manufactures more than 35% of the health technology produced in Spain. Also the important investment in Barcelona by Novartis in an antibiotic center.

BIOMEDICINE

GLOBAL HEALTH

INTERNATIONAL HEALTH POLICY

NATIONAL HEALTH POLICY (SPAIN)

  • COVID

o The incidence of COVID drops to 463 per 100,000 inhabitants, but the decreases are smaller than in previous weeks and the figure of more than 150 deaths per day continues (https://www.consalud.es/pacientes/especial-coronavirus/covid-19-espana-registra-22400-casos-174-muertes-ia-desciende-463-puntos_111057_102.html)

o 100,000 (official) deaths from COVID in Spain (https://www.redaccionmedica.com/secciones/sanidad-hoy/espana-supera-los-100-000-muertos-por-covid-desde-el-inicio-de-la-pandemia-7926)

o The Ministry of Health will give COVID data twice a week instead of daily (https://www.elconfidencial.com/espana/2022-03-02/sanidad-pasara-dar-datos-covid-dos-veces-por-semana-en-lugar-de-a-diario_3384902/)

  • Political announcements

o The bill project amending the National Security Law is published (https://www.congreso.es/public_oficiales/L14/CONG/BOCG/A/BOCG-14-A-91-1.PDF)

o The bill project amending the Law on Science, Technology and Innovation is published (https://www.congreso.es/public_oficiales/L14/CONG/BOCG/A/BOCG-14-A-92-1.PDF)

  • Other issues

o Catalonia wants to extend pharmacological abortion up to 14 weeks (https://elpais.com/espana/catalunya/2022-03-02/cataluna-quiere-ampliar-el-aborto-farmacologico-hasta-las-14-semanas.html)

o Spain will send more than 20 tons of medicines and medical supplies to Ukraine (https://www.elindependiente.com/espana/2022/02/26/espana-enviara-20-tonadas-de-medicinas-y-material-sanitario -to-ukraine/)

o The autonomous communities offer 3,000 beds to care for the victims of Ukraine (https://www.elespanol.com/espana/politica/20220227/ccaa-ofrecen-hospitalarias-acoger-victimas-invasion-ukrania/653434701_0.html)

o Spain joins the health PERTE at European level (https://www.lamoncloa.gob.es/serviciosdeprensa/notasprensa/industria/Paginas/2022/030322-ipceisalud.aspx)

COMPANIES, EMPLOYERS AND OTHER AGENTS IN THE SECTOR

 

 

7 days in healthcare (February 21-27, 2022)

SUMMARY

From the point of view of biomedicine, Bill Gates predicts another pandemic, although he estimates that he will catch us better prepared. Also to highlight the questioning of the traditional form of clinical trials. The latter is important, since Spain has become a power in clinical trials and it is important to analyze whether it is the right bet.

In terms of global health, it should be noted that COVAX has distributed exactly half of the COVID vaccines that it had as its objective. A great inequity in the distribution of vaccines in the world and, now, also of medicines against COVID.

As for international health policy, great controversy in the United Kingdom due to the lifting of all restrictions against COVID.

In national health policy (Spain), the incidence of COVID is low, although we continue with high mortality and without antivirals. The Ministry of Health takes the expansion of the service portfolio to a public hearing. Medical uneasiness before the reform of the Abortion Law, a BIOSIM proposal to promote the use of biosimilars and controversy over the financing of orphan drugs.

With regard to companies, it should be noted that the manufacture of Ventolín and Nolotil pollutes more than the automotive industry, which indicates how far the pharmaceutical industry has to go in implementing the United Nations Sustainable Development Goals. Also that Quirónsalud has exceeded the turnover of 4,000 million and Fresenius is open to incorporating new shareholders both in Quirónsalud and Eugin.

BIOMEDICINE

GLOBAL HEALTH

INTERNATIONAL HEALTH POLICY

NATIONAL HEALTH POLICY (SPAIN)

  • COVID

o The incidence of COVID continues to drop to 613 cases per 100,000 inhabitants (https://elpais.com/sociedad/2022-02-24/ultima-hora-del-coronavirus-hoy-en-espana-y-el-mundo-en-directo.html)

o 245 deaths in the sixth wave and still without antivirals (https://www.larazon.es/sociedad/20220225/3eq7hmpczjfe3ct7ruk3tz56wi.html)

o The subvariant of the stealthy “ómicron” accelerates its expansion in Spain (https://www.larazon.es/sociedad/20220224/3zfep56h6bf7jktf4fqvbnj3yq.html)

  • Political announcements

o The Ministry of Health takes out the draft order for the expansion of the service portfolio for a public hearing. Opinions in this regard can be sent via email informacion.publica@mscbs.es until March 10 (https://www.consalud.es/politica/sanidad-saca-audiencia-publica-orden-ministerial-actualiza-cartera-comun-sns_110420_102.html)

o AIReF announces a study on MUFACE spending in its plan for 2022 (https://www.airef.es/es/noticias/la-airef-publica-su-plan-de-actuaciones-2022-con-una-apuesta-clara-por-la-sostenibilidad-y-la-evaluacion/)

  • Other issues

o The medical groups, against the reform of the abortion law, propose the obligatory nature of performing it in public hospitals (https://www.larazon.es/sociedad/20220225/onwymfclwbbyfiamuan5il533e.html)

o Biosim presents 14 proposals to stimulate the use of biosimilars (https://www.diariofarma.com/2022/02/24/biosim-plantea-14-propuestas-para-fomentar-el-uso-de-los-biosimilares )

o Great controversy over the financing of orphan drugs, while the Ministry publishes a report with improvements in financing since 2016 (https://www.diariofarma.com/2022/02/23/sanidad-publica-un-analisis-sobre-la-financiacion-acceso-y-gasto-de-los-medicamentos-huerfanos-desde-2016) others insist that more than 50% of these medicines are not publicly funded (https://www.redaccionmedica.com/secciones/industria/el-50-de-los-medicamentos-huerfanos-estan-sin-financiar-en-espana-7267)

o The strategic health reserve today has 466 million masks and 955 respirators (https://www.elindependiente.com/espana/2022/02/27/la-reserva-estrategica-de-sanidad-cuenta-hoy-con-466-millones-de-mascarillas-y-955-respiradores/)

COMPANIES, EMPLOYERS AND OTHER AGENTS IN THE SECTOR

 

7 days in healthcare (February 14-20, 2022)

 

 

 

SUMMARY

In biomedicine, we have to highlight the studies that are confirming a modest association between an increased incidence of mental illness after COVID.

As far as Global Health is concerned, mention should be made of the book by Ed Miliband, a British parliamentarian, former leader of the Labor Party and minister with Gordon Brown, which amounts to a manifesto on public health in the wider sense, which, at the moment, is already beginning to be a literary genre, among which the books by Gordon Brown, Minouche Shafik, Fareed Zakaria and, soon, Bill Gates stand out.

Regarding international health policy, verifying that the calculation of excess mortality is the best way to assess mortality from COVID. The problem is that this may be valid for Europe and the Americas, but not for Asia and Africa, where the low mortality figures are hardly credible. Gordon Brown, former British Prime Minister, asks the G20 for a global financial solution to tackle the pandemic, similar to what was done in the 1960s with smallpox. The Economist highlights Africa’s low capacity for vaccine production, in contrast to its large population.

Regarding the national health policy, the first thing to mention is the drop in the incidence of COVID, which last Friday reached 919 per 100,000 inhabitants, which is compatible with the fact that mortality skyrockets in the sixth wave and there is a delay in receiving the new antivirals. The government approves the Science Law project, with controversial elements among researchers. The massive retirement of professionals (including doctors) is probably the most far-reaching problem of the SNS. The SEOM (Spanish Society of Medical Oncology) denounces the lack of equity in access to drugs and markers.

In business news, we must mention the FENIN declaration in favor of the manufacture of medical technology in Spain, to avoid dependency in the event of pandemics; also that the fifth vaccine approved in Europe (NOVAVAX) receives authorization to be manufactured in Galicia (Porriño); Rovi extends its alliance with Moderna for the manufacture of vaccines for ten years.

BIOMEDICINE

GLOBAL HEALTH

INTERNATIONAL HEALTH POLICY

NATIONAL HEALTH POLICY (SPAIN)

  • COVID

o The incidence of COVID drops to 919 cases per 100,000 inhabitants, with 7.8% occupancy of hospital beds due to COVID and 13.7% of ICU beds (https://www.consalud.es/pacientes/especial -coronavirus/covid-19-spain-records-30615-cases-288-deaths-ia-baja-919_110353_102.html)

o Deaths from covid skyrocket in the sixth wave (https://www.elindependiente.com/vida-sana/salud/2022/02/19/las-muertes-por-covid-se-disparan-en-febrero-con-4-365-fallecidos-y-elevan-a-11-081-las-de-la-sexta-ola/)

o Waiting for the antivirals that Sánchez promised in January (https://www.elespanol.com/ciencia/salud/20220214/omicron-mata-espera-antivirales-sanchez-prometio-enero/650185438_0.html)

o Public health detects an explosion of scabies cases related to the pandemic (https://elpais.com/sociedad/2022-02-19/la-sanidad-publica-detecta-una-explosion-de-casos-de- scabies-related-to-the-pandemic.html)

o Sports events capacity returns to 100% on March 4 (https://www.consalud.es/politica/consejo-interterritorial-decide-recuperar-aforos-deportivos-100-4-marzo_110196_102.html)

  • Political announcements

o The Government approves the Science Law project that the sector sees with room for improvement (https://www.diariomedico.com/investigacion/el-gobierno-aproba-una-ley-de-ciencia-que-los-investigadores-ven-muy -improveable.html?check_logged_in=1)

o Changes in the portfolio of services: more oral health and screening (https://www.redaccionmedica.com/secciones/ministerio-sanidad/la-nueva-cartera-comun-del-sns-contempla-mas-salud-bucodental- y-screened-6455)

o Spain adheres to the International Vaccine Institute (https://www.consalud.es/politica/gobierno-aprob-adhesion-espana-instituto-internacional-vacunas_110110_102.html)

  • Other issues

o Health approves the new vaccination schedule for 2022 (https://www.larazon.es/sociedad/20220217/as5pmub735hwpmxosjjwlzapty.html)

o Strong mobilizations in the Andalusian health sector (https://www.elconfidencial.com/espana/andalucia/2022-02-19/sanidad-andalucia-manifestaciones-sindicatos-partidas_3378408/)

o Mass retirement of health workers: a drag on the SNS (https://www.consalud.es/profesionales/jubilacion-masiva-sanitarios-quebradero-cabeza-sistema-nacional-salud_110332_102.html)

o Private healthcare demands a clear legal framework in the National Security Law (https://www.redaccionmedica.com/secciones/privada/la-privada-reclama-un-marco-juridico-claro-en-la-nueva- security-law-8788)

o Lack of equity in access to drugs and markers (https://cincodias.elpais.com/cincodias/2022/02/16/companias/1645013239_112550.html)

COMPANIES, EMPLOYERS AND OTHER AGENTS IN THE SECTOR

7 days in healthcare (February 7-13, 2022)

SUMMARY

From the point of view of biomedicine, to highlight the advances that allow paraplegics to walk, through spinal implants.

Regarding Global Health, it is worth mentioning the WHO warning that the pandemic has threatened the health systems of 90% of the countries; as well as the health problems in Burkina Faso and Afghanistan.

In relation to international health policy, the WHO statement that the pandemic is not over and that more variants are expected should be highlighted. In some countries the restrictions are lifted (United Kingdom, Norway) while in others (Germany) they continue. HERA (the new European Authority for Preparedness and Response to Health Emergencies) begins its steps and will receive a budget of 1,300 million euros in 2022.

In national health policy, we are witnessing a relaxation of the restriction measures, as a consequence of the decrease in the figures of the pandemic (less than 1,500 per 100,000 inhabitants), although these figures are still high and are accompanied by high mortality. Nor is the appearance of new variants ruled out. On the other hand, in the face of loud announcements by the Government, the incorporation of Paxlovid, Pfizer’s medication against serious cases of COVID, is delayed. Work begins for the creation of the State Public Health Surveillance Network, one of the conclusions of the work of the Commission for Social and Economic Reconstruction of the Congress of Deputies of July 3, 2020 (point 19.2), although in the conclusions of the commission there was talk of “urgently implementing” this issue. It is addressed two years after the first death from covid. Also noteworthy is the great concern and mobilizations carried out by the nursing sector. The General Council of Nursing Colleges publishes a Decalogue, whose first point is “Spain without nurses” and the last “Enough of ignoring us”. Spain leads the consumption of anxiolytics, which does not seem like a minor problem.

As far as company news is concerned, mention should be made of the FDA’s delay in approving Pfizer’s vaccine for children under 5 years of age. Also the entry of Nestlé in the field of health, positioning itself in weight control.

BIOMEDICINE

  • Spinal implants allow paraplegics to walk, swim and ride a bike. Breakthrough driven by Grégoire Courtine, a neuroscientist at the Federal Institute of Technology in Lausanne, and Jocelyne Bloch, a neurosurgeon at Lausanne University Hospital. The rupture of the cord prevents the transmission of electrical signals from the brain, which allows the implanted device (The Economist, 12 February 22)
  • There is a lack of evidence that current covid vaccines will produce herd immunity (American Journal of Medicine, February 6, 22)
  • A study analyzes the prevalence of loneliness in 113 countries, as a major health and social problem (BMJ, February 9, 22

GLOBAL HEALTH

  • The WHO warns that more than 90% of the countries have seen their health system threatened by the pandemic (interruptions in services, difficulties in accessing care, problems with emergency care) (La Razón, February 7, 22)
  • The WHO denounces actions by the pharmaceutical industry that make it difficult to bring covid vaccines to Africa. The declaration affects a foundation (kENUP) linked to BioNTech (BMJ, February 9, 22)
  • The armed conflict in the Sahel region (Burkina Faso) endangers the already weak health system (The Lancet, February 12, 22)
  • Afghanistan’s health system is collapsing under stress (NYT, February 6, 22)
  • Ukraine, fears that a health system that had made great progress in recent times is going into crisis due to the possible conflict (The Lancet 12 February 22)

INTERNATIONAL HEALTH POLICY

  • COVID

o The WHO warns that the pandemic is not over and that more variants are expected (ABC, February 12, 22)

o Covid levels remain high in many parts of Europe, but restrictions tend to be lifted (FT, February 11, 22)

o The 1918 flu had devastating effects the third year (Washington Post, February 6, 22)

o Protests against covid restrictions in France and the Netherlands (The Guardian, February 12, 22)

o Waiting lists in England exceed 6 million for the first time (FT, 10 February 22)

o Boris Johnson plans to end the restrictions due to covid a month earlier than planned (The Guardian, February 9, 22)

o China, ready to impose greater confinements in Hong Kong (FT, February 11, 22)

o A study detects that NYC deer are infected by covid (NYT, February 7, 22)

o Seven out of ten vaccines administered in the EU are from Pfizer (El Español, February 11, 22)

o Norway lifts all restrictions against the pandemic (El País, February 13, 22)

o Germany will not lift the restrictions against covid (El Mundo, February 10, 22)

  • Other issues

o HERA (the new European Authority for Preparedness and Response to Health Emergencies) will have a total budget of 1,300 million in 2022 (diariofarma, February 10, 22)

o The EFPIA publishes a white paper on the effectiveness of public procurement of medicines in the EU (EFPIA, February 22)

o It seems that the attempts of the United States government to lower the price of medicines by allowing the negotiation of their prices in Medicare are failing (NEJM, February 9, 22)

NATIONAL HEALTH POLICY (SPAIN)

  • COVID

o The low incidence of 1,500 cases per 100,000 inhabitants in Spain, although with 389 deaths on the last day with official information (La Vanguardia, February 11, 22)

o Delays in the incorporation of Paxlovid, Pfizer’s medication against severe COVID (El Periódico de España, February 11, 22)

  • Political announcements

o Spain begins to create the pandemic alert network, creating the State Public Health Surveillance Network (El Español, 13 February 22)

  • Other issues

o The nursing sector stars in demonstrations throughout Spain (La Razón, February 9, 22)

o Decalogue published by the General Council of Nursing Colleges (CGCE, February, 2022)

o Spain leads the consumption of anxiolytics in Europe, according to the latest report from the Narcotics Control Board (INCB), more than 2.5 million people consume psychotropic drugs daily (La Razón, February 12, 22)

o Spain doubles the number of leprosy cases in 2021 (The Objective, February 7, 22)

o The OMC (Collegiate Medical Organization), against Montero’s campaign on “obstetric violence” (El Español, February 10, 22)

o The Ombudsman intervenes in response to complaints of health cuts to MUFACE officials (La Razón, February 10, 22)

o In a meeting convened by the IMAS Foundation, specialists demand a digital health strategy (Health Act, February 9, 22)

o Cantabria wants to turn Valdecilla into a reference in precision medicine (Sanitary Act, February 10, 22)

COMPANIES, EMPLOYERS AND OTHER AGENTS IN THE SECTOR

  • Important medical bet by Amazon that is revolutionizing the health system in the USA (El Economista, February 12, 22)
  • The FDA puts a brake on the approval of Pfizer’s covid vaccine below 5 years (The Guardian, February 11, 22)
  • Novavax, the fifth vaccine, arrives in Europe the last week of February (diariofarma, February 10, 22)
  • China conditionally approves Pfizer’s treatment Paxlovid (The Guardian, 12 February 22)
  • CEOE: Adriana Bonezzi, new head of the health area (Medical Writing, February 7, 22)
  • Wivi vision. company that evaluates the capabilities of the visual system: agreement with General Óptica to implement it in its network of stores (PlantaDoce, February 8, 22)
  • Vithas joins forces with Genesis Care to launch a cancer center in Madrid (PlantaDoce, February 4, 22)
  • Pfizer more than doubles its profits in 2021, up to 22,000 million dollars (PlantaDoce, February 8, 22)
  • Nestlé Health Science buys Pronokal, positioning itself in the weight loss and control products sector (Diario Médico, February 7, 22)
  • J&J suspends the manufacture of its vaccine (Consalud, February 11, 22)
  • Dependency insurance grows 96% and closes 2021 with 128,000 insured (PlantaDoce, February 7, 22)
  • Durcal relies on Movistar to break into the elderly care segment (PlantaDoce, February 10, 22)
  • Nordic Cap and Amulet enter the bid for the IVI group, Morgan Stanley will receive the non-binding offers before February 23 (CincoDías, February 12, 22)