Posts

7 days in healthcare (December 12th-18th, 2023)

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Summary

From the point of view of Biomedicine, The Lancet commemorates the 200th anniversary of the birth of Pasteur, the creator of the germ theory. Even today a high percentage of deaths are from infections. Promising results of an mRNA vaccine against melanoma, presented by Moderna and Merck.

As far as Global Health is concerned, it is worth highlighting the article published in Nature that says that without a strategy and global financing of vaccines, the world will be unable to successfully face new epidemics.

As for international health policy, the discouraging news of China’s abandonment of the covid-zero policy continues, when the country is not prepared and is most likely to suffer high mortality. The CDC quantifies the deaths from persistent covid in the USA. The conflict of nurses in the NHS continues, which coincides with the appearance of a report from the Institute for Fiscal Studies in the United Kingdom that attributes the problems of the NHS to underfunding of the system. New Zealand, the second country in the world to announce a ban on tobacco sales.

If we talk about national health policy (Spain), in terms of covid, the incidence continues to decrease, what has not completely decreased, or has decreased very slowly, is mortality (236 deaths in the last week). After confinement in a unit of the Regional Ministry of Health, the strike committee of primary care doctors in Madrid decided to continue the strike, extending the conflict to a demonstration, along the lines of the “white tides”.

In the field of companies, internationally, it seems that Jeff Bezos and Bill Gates are making an important bet in the field of neurotechnology with the company Synchron. As far as national news is concerned, perhaps highlighting that it seems that the hopes placed on the Spanish HIPRA vaccine are fading.

Biomedicine

Global Health

International Health Policy

National health policy

Companies

 

 

 

7 days in healthcare (May 16th-22nd, 2022)

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Summary

From the point of view of biomedicine, there seems to be new evidence of the relationship between acute childhood hepatitis and COVID. Interesting articles on how COVID can affect the brain, generating a kind of “dementia epidemic” and what long covid is and how to treat it.

Regarding Global Health, possible alarming effects of a global food crisis resulting from the war in Ukraine and its consequences. Report on serious deficiencies of “assisted technologies” (basically, wheelchairs, glasses and hearing aids) in a large part of the world’s population. The shortage of covid vaccine production in African countries continues to be denounced.

As for international health policy, an article in The Economist takes the drama out of “monkey pox”, saying that it is nothing comparable to what covid represented. Catastrophe due to covid in North Korea, a country that did not take advantage of its total closure during the pandemic to favor the immunization of its population and the reinforcement of its health system. Also, very reluctant to accept foreign aid. Isolated dictatorship things. Interesting experiment in New Zealand on a generation without tobacco.

If we talk about national health policy (Spain), the Ministry of Health has issued a protocol on monkeypox, about which there are some interesting statements by López Acuña, who also takes the drama out of this epidemic. Approved in the Council of Ministers the new abortion law, destined, probably, not to solve anything and to generate artificial problems. The SEMFYC (association of primary care doctors) warns about the need for 10,000 primary care doctors, to cover the generational change.

In the field of companies, the initiative of the Government of Catalonia to create a commission to study the new location of the Hospital Clínic should be highlighted. Surely an avant-garde and innovative hospital does not fit well in the current old building. A true revolution in the hospital and urban world of Barcelona. The AESEG warns about the low price of certain basic medicines, which discourages their production.

Biomedicine

Global health

International health policy

  • Monkeypox

o Monkeypox spreads to several countries: after originating from a traveler from Nigeria, the disease has spread to the United States, Australia, Canada and 8 European countries. According to The Economist, there is nothing to worry about and it has nothing to do with the covid pandemic, which took the world unprepared, without vaccines or treatments (https://www.economist.com/the-economist-explains/2022 /05/20/monkeypox-is-popping-up-in-more-countries-how-worrying-is-this)

o What is Monkeypox, article in the New York Times (https://www.nytimes.com/article/what-is-monkeypox.html)

o We will see more cases of monkeypox, warns a British scientist (https://www.theguardian.com/world/2022/may/21/we-will-see-more-cases-of-monkeypox-warn-british- scientists)

  • COVID-19

o Taiwan gradually renounces the “zero-covid” policy, assuming that the number of cases will increase (https://www.lemonde.fr/planete/article/2022/05/16/taiwan-renonce-peu -a-peu-a-politique-zero-covid_6126267_3244.html)

o Catastrophe in North Korea. The country was closed during the pandemic, but it was not used to immunize the population or strengthen the health system (https://www.economist.com/asia/2022/05/17/covid-19-is-spreading-like -wildfire-in-north-korea)

o Shanghai is going to open its commerce in stages (https://www.lemonde.fr/planete/article/2022/05/15/covid-19-shanghai-va-rouvrir-ses-commerces-par-etapes-apres- deux-mois-de-confinement_6126204_3244.html)

o How Australia saved thousands of lives from covid, in contrast to what happened in the United States (https://www.nytimes.com/2022/05/15/world/australia/covid-deaths.html)

  • Other themes

o The policy on the possible annulment of the Roe v Wade judgment in the United States continues, important editorial in Science (https://www.science.org/doi/10.1126/science.adc9968)

o A generation without tobacco in New Zealand, prohibited for all those born since January 1, 2009. Malaysia and Denmark are also considering similar measures (https://www.thelancet.com/journals/lancet/article/PIIS0140- 6736(22)00925-4/fulltext)

o The United States, Switzerland and Norway lead the world in spending on health per capita (https://www.plantadoce.com/entorno/estados-unidos-suiza-y-noruega-lideran-el-gasto-per-inhabitante- in-medical-care.html)

o The NHS needs access to medical data to save lives, interesting article in the Financial Times (https://www.ft.com/content/dc01b30f-472d-4da6-b694-28486383aeff)

o A report commissioned by the Minister for Health proposes that the legal smoking age in the UK be 21 (https://www.theguardian.com/society/2022/may/21/legal-smoking-age -in-england-could-be-raised-to-21-report)

National health policy

  • Monkeypox

o Protocol of the Ministry of Health against monkeypox (https://www.consalud.es/pacientes/protocolo-contra-viruela-mono-aislamiento-cuarentena-solo-confirmados-sopechosos_115004_102.html)

o Interesting statements by López Acuña: there is no reason for social alarm over monkeypox (https://www.elmundo.es/ciencia-y-salud/salud/2022/05/22/62890984e4d4d80e098b4591.html)

o Spain will buy thousands of vaccines for the monkeypox disease (https://elpais.com/sociedad/2022-05-19/espana-prepara-la-compra-de-miles-de-vacunas-frente-a -the-traditional-smallpox-to-deal-with-the-monkey-virus-outbreak.html)

  • COVID

o The cumulative incidence, on the rise: 848 points (https://www.consalud.es/pacientes/especial-coronavirus/covid-19-espana-notifica-58839-nuevos-casos-305-muertes-ia-sube-848 -points_114982_102.html)

  • Regulatory announcements

o The new abortion law approved by the Council of Ministers (https://www.diariomedico.com/medicina/ginecologia/politica/montero-las-mujeres-podran-abortar-en-el-hospital-publico-mas-cercano- your-address.html)

  • Other themes

o Spain, leader in the consumption of benzodiazepines for anxiety and insomnia (https://www.elmundo.es/ciencia-y-salud/salud/2022/05/15/627e8bf0fdddffa9638b458b.html)

o The National Health System (SNS) would need 10,000 family doctors for generational turnover, according to a study by the Spanish Society of Family and Community Medicine (SEMFYC) (https://www.plantadoce.com/entorno/el-sns-necesita-10000-medicos -of-family-more-to-guarantee-the-generational-handover.html)

o The strike of specialist doctors in Madrid, suspended after an agreement (https://www.diariomedico.com/medicina/profesion/madrid-medicos-desconvocan-la-huelga-con-la-promesa-de-2500-plazas- contest.html)

o Spain, last in mental health, there are only 2,800 psychologists in public health, only 344 in Primary Care (https://www.elespanol.com/invertia/observatorios/sanidad/20220522/espana-mental-invierte-europa -psychologists-public-health/672183163_0.html)

o Private healthcare works on a code of good practice: joint initiative of ATA (Association of Self-Employed) and ASPE (https://www.redaccionmedica.com/secciones/privada/la-sanidad-privada-espanola-trabajo-en- your-own-code-of-good-practices-4162)

Companies

  • International News

o Big Pharma pressures the G20 to prepare for the next pandemic (https://www.ft.com/content/ca71ee0e-9b4b-4c2e-b60b-bbd841415697)

o Monkeypox shoots up the stock of the only company that manufactures them: Bavarian Nordic (https://cincodias.elpais.com/cincodias/2022/05/20/companias/1653035794_646119.html)

  • National News

o Dependency insurance grows 71.4% and closes the first quarter with 132,000 users (https://www.plantadoce.com/entorno/el-seguro-de-dependencia-crece-un-714-y-cierra- the-first-quarter-with-132000-users.html)

o Catalonia constitutes the commission that will decide the location of the new Clinic Hospital (https://www.plantadoce.com/publico/cataluna-constitución-la-comision-que-decidira-el-emplazamiento-del-nuevo-hospital-clinic. html)

o Colgate-Palmolive breaks into the bid for Lácer (https://cincodias.elpais.com/cincodias/2022/05/19/companias/1652978299_749683.html)

o AESEG asks to raise the price of essential medicines to produce them (https://www.eleconomista.es/salud/noticias/11768114/05/22/El-generico-pide-subir-el-precio-de-los-farmacos -essential-to-produce-them.html)

 

 

7 days in healthcare (January 31-February 6, 2022)

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SUMMARY

As far as biomedicine is concerned, the report on the value of death by The Lancet stands out; also the development of the nasal vaccine against COVID; the new horizon of transplants, derived from the possibilities of genetic editing of animal organs; and, the revolution that the new cancer vaccines based on mRNA technology may entail.

In terms of global health, the AstraZeneca vaccine is the most widely used worldwide, due to its contribution to COVAX. More than 2,500 million doses have been placed globally.

In international health policy, the most striking is the study by Johns Hopkins University, which minimizes the effectiveness of confinement, which contrasts with previous studies; the 900,000 deaths from COVID in the United States and the 500,000 in India; the WTO continues to request the release of vaccine patents. In Europe, it is worth highlighting the new clinical trial system approved by the European Union and its new approach to cancer.

National health policy continues to be dominated by COVID. The numbers of cases are decreasing, which speaks of the decline of the “sixth wave”. However, deaths are still very high. The announcement that oncological biomarkers will be included in the portfolio of the National Health System is very important. Cancer mapping in Spain presents very striking results, with a high concentration of cancer incidence in certain geographical areas. Subject to study and act.

In company news, the leading role of venture capital companies is notable, with the large operations underway by Sandoz (a generic and biosimilar branch of Novartis) and IVI (a Spanish fertility company). The interest of private equity companies is concentrated around these companies. Also the acquisition of MIR Asturias by CVC and the Alfonso X University. The attempt by Correos to enter pharmaceutical distribution will bring a tail.

BIOMEDICINE

  • Report on the value of death: while in developed countries there is hypertreatment around death, in most countries death occurs without access to basic pain treatment (The Lancet, January 31, 22)
  • The nasal vaccine may be better for successive doses. There are a dozen such vaccines in development in phase 3 trials (NYT, February 2, 22)
  • The “stealth” variant (stealth) does not generate alarm, but it can slow down the decline in the number of cases (NYT, January 31, 22)
  • The sub-variant “ómicron” BA.2, more contagious than the original (FT, 31 January 22)
  • The new variant BA.2, already present in 57 countries, according to the WHO (FT, February 3, 22)
  • New variant of the HIV virus, discovered in the Netherlands (FT, February 3, 22)
  • Genetic editing of pig hearts: a new horizon for transplants (FT, February 2, 22)
  • Cancer vaccines: the new mRNA revolution (El País, Vozpópuli, February 4, 22)
  • Amidst the wide debate on abortion, a simple pill seems the most viable option (The Economist, 5 February 22)

GLOBAL HEALTH

  • AstraZeneca, the most distributed vaccine through COVAX, has already given 2,500 million doses worldwide (ConSalud, January 31, 22)
  • Humanitarian groups denounce that sanctions against Mali may have very adverse health consequences (The Lancet, February 5, 22)

INTERNATIONAL HEALTH POLICY

  • COVID

o A study by Johns Hopkins University (Applied Economics Studies magazine) questions the effectiveness of confinement in reducing mortality, which contrasts with the analysis published in Nature in June 2020, which estimates that three million deaths have been prevented in Europe by confinement, 450,000 in Spain (El Independiente, February 3, 22)

o The UK approves the Novavax vaccine (FT, 3 February 22)

o The American army begins to fire its members who refuse the vaccine (The Guardian, February 2, 22)

o The New Zealand border will be reopened in phases from the end of February, the Prime Minister announces (The Guardian, 2 February 22)

o The United States reaches 900,000 deaths from COVID (The Guardian, February 4, 22)

o India exceeds 500,000 deaths from COVID (The Guardian, February 4, 22)

o Europe facing a “long period of tranquility” in the pandemic, says the WHO, due to the lesser severity of the “ómicron” variant, the high percentages of immunization and the good weather (The Guardian, February 3, 22)

o The WTO (World Trade Organization) wants an agreement to release vaccine patents this month (El Español, February 1, 22)

o The German Vaccine Commission recommends the fourth dose for vulnerable and health groups (El País, February 3, 22)

o Beijing seals off several communities for two cases of COVID (The Guardian, January 31, 22)

o The COVID vaccine is already mandatory in Austria, with a great social fracture (Expansión, February 5, 22)

  • Other issues

o New clinical trial system in Europe, which Farmaindustria sees as an opportunity (diariofarma, February 1, 22)

o The EU will act against inequalities against cancer (ConSalud, February 3, 22)

NATIONAL HEALTH POLICY (SPAIN)

  • COVID

o The sixth wave is being left behind, the cases and hospitalizations are slowing down, although not the deaths that already exceed 6,000 since November (El País, February 5, 22)

o The mask outdoors will no longer be mandatory from next Thursday (El País, February 4, 22)

o Health has not yet closed the purchase of 344,000 doses of Paxlovid (El Español, February 3, 22)

o The AEM authorizes the HIPRA vaccine to go to phase 3 of clinical trials (The Objective, February 1, 22)

  • Political ads

o The new public health center, affected by the decentralization of public offices (diariofarma, February 1, 22)

o The approval of oncological biomarkers, announced as a pending objective of the expansion of the NHS portfolio (diariofarma, February 1, 22)

o The Minister of Health says that the Anti-Tobacco Law needs to be updated (ConSalud, February 4, 22)

  • Other issues

o 27% of pharmaceutical innovations approved in 2021, subject to special financing conditions (diariofarma, February 1, 22)

o Access to new cancer drugs takes more than 19 months in Spain, while in Germany it takes two months, according to doctors and patients (La Vanguardia, February 2, 22)

o Health plan to make rural pharmacies more viable (ConSalud, January 28, 2022)

o The private e-prescription is consolidated (diariofarma, February 2, 22)

o The cartography of cancer in Spain has been published, with very striking results, according to the “Atlas of Cancer Mortality in Portugal and Spain” (El Periódico de España, February 5, 22)

COMPANIES, EMPLOYERS AND OTHER AGENTS IN THE SECTOR

  • American pharmaceutical companies (J&J and three of the largest drug distributors in the United States) agree to pay 590 million dollars to Native Americans for the opioid crisis (El País, February 1, 22)
  • Pharmaceutical cold distribution, new Correos service (Redacción Médica, February 2, 22)
  • Pfizer-Biontech requests authorization from the FDA for the approval of the vaccine for children under 5 years of age (El País, February 1, 22)
  • Private equity companies consider offers of more than 25,000 million dollars for the generics unit of Novartis, Sandoz, Blackstone, Carlyle and EQT, among the most interested (FT, February 1, 22)
  • KKR, CVC, Permira, Bain, Carlyle and PAI outline their bids to take over the fertility company of Valencian origin IVI, the bids range from 1,500 million euros (CincoDías, January 31, 22)
  • Atrys enters the continuous market, as of February 7 (PlantaDoce, February 3, 22)
  • Sanitas gains ground and plans to open 7 rehabilitation centers in 2022 (PlantaDoce, February 1, 22)
  • Adeslas and Caixabank extend their agreement in the Bankia network for 650 million euros (CincoDías, January 27, 22)
  • MIR Asturias acquired by CVC and Alfonso X University (La Nueva España, February 3, 22)
  • Quirón acquires Clínicas Vida and strengthens its care network in Tenerife (PlantaDoce, January 28, 22)
  • Vitaldent expands throughout Andalusia and opens a new clinic in Benalmádena (PlantaDoce, February 3, 22)
  • Group 5 opens a residence for serious mental disorders in Madrid (PlantaDoce, February 3, 22)
  • Prim is reinforced with the purchase of Herbitas laboratories (Expansión, February 4, 22)
  • Pharmamar leads a consortium of companies for the development of advanced therapies (El Economista, February 3, 22)

7 days in healthcare (January 24-30, 2022)

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Summary

From the point of view of biomedicine, the concern regarding resistance to antibiotics continues, after the extensive report published by The Lancet. This pandemic produces more deaths than AIDS and malaria. New variant of “ómicron” appeared in Denmark.

With regard to global health, the tenth anniversary of the declaration on “Neglected tropical diseases” should be highlighted, which provides an opportunity to reflect on a change in which progress has been made, but much remains to be done. COVAX does not have the capacity to receive more donations in the absence of basic financing for the purchase of syringes and other materials, essential to administer the vaccine.

As for international news, the WHO will publish a plan for the transition of the pandemic to the “control phase” in February. IHI initiative, of the European Union, to create a public/private platform for drug research.

In national news from Spain, the sixth wave seems to be starting to subside in terms of new cases, but still with high mortality. Interesting report promoted by Vitaldent on the public financing of dental care. Biosim highlights the savings potential of biosimilars in 2022. The issue of professional recertification advances, with a leading role for FACME.

In company news, the approval by the EMA of Paxlovid, Pfizer’s antiviral pill against COVID, is important. Also the large expected growth in turnover by COVID vaccine manufacturers in 2022 (29%, compared to 2021). Boom of online psychology platforms

Biomedicine

  • It is time to confront the pandemic of antibiotic resistance, since this resistance causes more deaths than AIDS and malaria. AMR Action Fund, a public/private initiative to develop new antibiotics, is underway (FT, January 28, 22)
  • The new BA.2 omicron, which appeared in Denmark, the stealthy variant of the “‘omicron”, warns the WHO that it may not be detectable with PCR (La Razón, January 25, 22)
  • New research identifies the 4 factors that can favor prolonged covid (NYT, January 25, 22)

Global health

  • 10th anniversary of the London declaration on “Neglected tropical diseases”, much progress has been made. Trachoma, schistosomiasis and visceral leishmaniasis are the most frequent of this type of disease (The Lancet, January 29, 22)
  • Developed countries throw away 61.5 million vaccines for having expired in 2021 (El Español, January 28, 22)
  • World Day against Leprosy, the covid pandemic has silenced it, a disease almost eradicated in Europe but still present in the world (ConSalud, January 30, 22)
  • Lack of funding to buy syringes and other accessories means COVAX cannot accept new doses of vaccines (FT, 25 Jan 22)
  • The United States donated 400 million doses of covid vaccine to 112 countries, according to the White House (The Guardian, January 26, 22)
  • Project Syndicate magazine publishes an analysis (How Much Has the Pandemic Cost?) of the economic impact of the pandemic, based on years of life lost and the value of life in different countries. If the official figure of 5.6 million dead at the end of 2021 is taken, this means 38 trillion (American) dollars or 40% of global GDP; If the estimate of deaths from The Economist (17 million) is taken, we would reach 114 trillion or 120% of global GDP (Project Syndicate, January 27, 22)

International News

  • The WHO will publish in February a plan for the transition of the pandemic to the “control phase” (La Razón, January 24, 22)
  • Notable increase in telemedicine in Medicare (USA) during the pandemic (JAMA, January 25, 22)
  • The British Medical Association recommends the use of FPP3 mask to health professionals who have to deal with patients with viral respiratory disease (BMJ, 21 January 22)
  • The new normal in New Zealand goes from covid 0 to covid acceptance (The Guardian, 26 January 22)
  • An Israeli panel recommends the fourth dose to all adults (FT 25 Jan 22)
  • In Canada, demonstrations against compulsory vaccination (The Guardian, January 30, 22)
  • The European Union launches IHI, a public/private initiative for drug research, as a continuation of the Innovative Medicines Initiative, which was launched in 2008 (Acta Sanitaria, January 26, 22)

National News

  • COVID

o The epidemic curve in Spain consolidates its decline, but experts call for caution (El País, January 29, 22)

o The sixth wave already registers 5,674 deaths from covid and could exceed the sixth before February (El Español, January 27, 22)

o Health and the communities extend the limited capacity at sporting events (El País, January 26, 22)

o The anti-vaccines are responsible for increasing deaths by 32% in the sixth wave, according to Fedea (El Español, January 24, 22)

o Those vaccinated have a hundred times less chance of dying if they become infected (El Mundo, January 28, 22)

o Catalonia abolishes the covid passport (La Razón, January 26, 22)

  • Other issues

o Financing dental health (one of the promises of the PSOE-Unidos Podemos government program) will cost the State 5,423 million euros, according to a study promoted by Vitaldent and presented to the Ministry of Health (El Economista, January 25, 22)

o A third of doctors will retire in the next five years (The Objective, January 28, 22)

o Telemedicine is good for reducing CO2 into the atmosphere, it would reduce 277,120 tons of CO2 in Spain in Primary Care alone, according to the report prepared by “GEN Europe Energy Solutions” (ConSalud, January 28, 22)

o More than 13,000 applicants opt for the 8,200 MIR places in the exam on January 29 (Acta Sanitaria, January 28, 22)

o Biosim puts the savings on biosimilars at 1,048 million euros in 2022 (diariofarma, January 26, 22)

o FACME claims its role in the recertification and creates a specific council, chaired by Cecilio Santander (Diario Médico, January 28, 22)

o ISFAS statement on difficulties in negotiating insurance companies-hospital groups for the coverage of this group (Sanifax, January 24, 22)

Companies, employers and other agents of the sector

  • The EMA approves Paxlovid, Pfizer’s antiviral pill against covid (El Economista, January 27, 22)
  • The large vaccine manufacturers will invoice 75,000 million euros for the covid vaccine this year 2022, this is a 29% jump over the estimate for 2021, according to the consulting firm Airfinity (CincoDías, January 25, 22)
  • Pfizer will produce 120 million doses of its drug against covid in Europe (El Español, January 29, 22)
  • Cinfa leads the market in pharmacies and Novartis in hospitals (CincoDías, January 24, 22)
  • The French group Orpea with problems in its listing due to accusations of mistreatment (FT, January 27, 22)
  • BioNTech begins clinical trial for “ómicron” vaccine (FT, January 25, 22)
  • The business of mental health: boom in online psychology platforms (El Periódico de España, 30 January 22)
  • Mifarma (the leading company in Europe for the online sale of pharmacy and parapharmacy products) reinforces its position in Spain with a new image and online platform (La Razón, January 25, 22)
  • United Imaging Healthcare lands in Spain hand in hand with APR Salud (PlantaDoce, January 25, 22)
  • Sanitas is interested in the purchase of the IMQ (Redacción Médica, January 26, 22)
  • Healthcare Activos continues its expansion and will buy a residence in Ferrol (PlantaDoce, January 21, 22)
  • Corachán becomes stronger in Barcelona with a new center in Sarriá (PlantaDoce, 27 January 22)