7 days in healthcare (June 24th-30th, 2024)
Summary
Biomedicine
- Advances in gene editing. Discovery of a new way to program DNA recombination. This increases the possibilities of the current CRISPR editing method. The new route is called the bridge RNA method.
- Lifestyles can compensate for genetics. Lifestyles can improve genetics by 60% and add 5 years to life.
Global Health
- Loneliness as a public health problem. Increases the chances of stroke by 56%. Given aging trends and changes in family structure, new ways to avoid loneliness will be a new public health problem.
- A disease control, prevention and control center for Latin America. Although Latin America has only 8.2% of the global population, in the case of covid they had 10% of the global cases and 25% of the mortality. A group of experts proposes the creation of a Latin American Center for the prevention and control of diseases.
- They propose warnings on ultra-processed foods. For some, ultra-processed foods need warnings, just like tobacco
- Simple steps to prevent people from dying from heat stroke. In Europe 70,000 people died from the heat wave in 2023. Saudi Arabia reached 50º in the shade; Baltimore and Philadelphia, around 40º; also India. Far from being exceptional episodes, it is part of the new normal. The solution is simple, according to The Economist: put people out of the sun and in a cool environment. Surely easier said than done.
International health policy
- Many Chinese doctors choose to leave the public sector to go to the private sector. The pressures of health reform on doctors cause many to opt for the private sector. The salary of doctors in China (equivalent to $13,000 per year on average) is lower than that of other Chinese professionals.
- Changes in the NHS in the electoral programs in the United Kingdom. The Lancet analyzes the health changes needed in the wake of the UK election. The NHS faces numerous challenges in many areas – from record waiting lists to repeated strikes – resulting in historic levels of dissatisfaction among patients and professionals. According to the Nuffield Trust think tank, none of the major parties promise a substantial increase in funding capable of addressing the serious problems.
National Health Policy (Spain)
- Plan for Primary Care. Health announces the approval of the AP and Community Action Plan in the last quarter of the year. We do not know if this will be a reality or a new song to the sun, to which the Ministry has accustomed us.
- Defense of the Catalan model of consortia. Mónica García defends the Catalan model, against criticism from Junts. She defends them because they are non-profit, as if having one would incapacitate collaboration with the public sector. Incredible.
- Hiring non-community doctors. Madrid extends the exception to hire non-European doctors in the public sector to all medical specialties. If a position remains unfilled, a non-EU doctor may apply for it, that is, whose medical degree has not been issued by the EU. Madrid is a pioneer in this measure, which, apparently, violates state law. If the law is really broken, it is doubtful that this could be the solution. In the United States there is the ECFMG (Educational Commission for Foreign Medical Graduates), the famous “Foreign”. And in Europe there are community directives that regulate the curricular contents of all health professions.
- A summer with 6,000 fewer doctors. The residents will finish later this year, due to the pandemic, and will not be able to fill the vacancies.
- Universal benefit for children between 0 and 3 years old. The CES calls for a universal benefit for children from 0 to 3 years old that is not conditioned by income. The starting point is that Spain has an “unheard of” problem, which does not correspond to its level of wealth, the weight of the Welfare State or its ethical values: one in three minors lives at risk of poverty or exclusion. social. The problem is especially serious from six months to three years.
- Statements by the prestigious health economist Félix Lobo. “It is not true that innovative therapies arrive late in Spain.” We need to know whether it is worth paying the high prices that pharmaceutical companies ask for medicines and health technologies, but we do not have good mechanisms to evaluate this. We need an organization independent of political power with means and prestige. It should be something similar to AIREF or the National Markets and Competition Commission (CNMC). Faced with these excellent statements, other groups propose populist solutions (in the sense of simple) to a complex problem and present the delays in the incorporation of new medications almost as the main problem of our health system, which is absurd and far from the reality.
- Tumors become the leading cause of death in Spain. 26.6% of deaths in 2023 were related to some type of cancer. It is the first time that this cause surpasses ailments of the circulatory system.
- Fertility rate in Spain. Below the OECD fertility rate and very far from the replacement level. We have gone from 3.3 children per woman in 1960 to 1.5 in 2022, below the replacement rate
Companies
- International
- A new market, that of exoskeletons. Aging is driving up the exoskeleton market, which will reach $1.5 billion by 2027. The prevalence of cerebrovascular accidents and the growing geriatric population are at the origin of this growth.
- aNovoNordisk, in China. Novonordisk’s obesity drug Wegovy approved in China.
- National
- Ribera diversifies into several communities. The Ribera health group expands its presence in new Autonomous Communities and prepares its landing in Andalusia. The announcement will be made in July.
- Esteve increases its production capacity. It will invest 100 million euros in building a new production unit in Girona.
Biomedicine
- Advances in gene editing promise great advances in the fight against the disease. Discovery of a new way to program DNA recombination. This increases the possibilities of the current CRISPR editing method. The method is called bridge RNA method (https://www.ft.com/content/b1b45c7e-b5e6-4f83-82b9-f1c32675674f)
- AI and the future of the pharmaceutical sector. The article defines six major trends in the pharmaceutical industry, driven by AI (https://medicalfuturist.com/the-ai-and-digital-health-future-of-pharma-prescription-for-change/)
- Spirituality as a determinant of health, according to a study published by Health Affairs. The sense of purpose and transcendence as determinants of health (https://www.healthaffairs.org/doi/10.1377/hlthaff.2023.01643)
- Food is medicine (https://www.healthaffairs.org/content/forefront/food-medicine-now-recognize-primarily-health-related)
- To cure the disease, AI needs our data (https://www.ft.com/content/03a636fd-aac4-427e-a393-31b4d08109d1)
- Lifestyles can improve genetics by 60% and add 5 years to life (https://www.theguardian.com/science/2024/apr/30/healthy-lifestyle-may-offset-genetics-by-60-and-add-five-years-to-life-study-says). Access to the original document: https://ebm.bmj.com/content/early/2024/04/16/bmjebm-2023-112583
Global Health
- Loneliness as a public health problem: increases the chances of stroke by 56% (https://www.theguardian.com/society/article/2024/jun/25/loneliness-can-increase-stroke-risk-by-up-to-56-finds-research)
- Why Latin America needs a disease control center. Although Latin America has only 8.2% of the global population, in the case of covid they had 10% of the global cases and 25% of the mortality. A group of experts proposes the creation of a Latin American Center for disease prevention and control (https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)00813-4/abstract)
- Monkeypox: WHO is concerned about the appearance of a new strain in the Democratic Republic of the Congo (https://www.lemonde.fr/afrique/article/2024/06/27/variole-du-singe-une-nouvelle-souche-plus-dangereuse-apparue-en-rdc-inquiete-l-oms-et-les-chercheurs_6244771_3212.html#:~:text=Plus%20transmissible%20et%20plus%20dangereuse,(OMS)%20mercredi%2026%20Jun.)
- Ultra-processed foods need warnings, just like tobacco (https://www.theguardian.com/global/article/2024/jun/27/ultra-processed-foods-need-tobacco-style-warnings-says-scientist )
- Article from The Economist: Simple steps to prevent people from dying of heat stroke. In Europe 70,000 people died from the heat wave in 2023. Saudi Arabia reached 50º in the shade; Baltimore and Philadelphia, around 40º; also India. Far from being exceptional episodes, it is part of the new normal. The solution is simple: put people out of the sun and in a cool environment (https://www.economist.com/leaders/2024/06/26/simple-steps-to-stop-people-dying-from-heatwaves#)
International health policy
- USA
- The Purdue opioid deal on the verge of collapse after a US Supreme Court ruling (https://www.nytimes.com/2024/06/27/health/purdue-pharma-sackler-opioid-supreme-court.html#:~:text=of%20Federal%20Agencies-,Purdue%20Opioid%20Settlement%20on%20Verge%20of%20Collapse%20After%20Supreme%20Court,in%20exchange%20for%20%246%20billion.)
- The Biden Administration opposes transgender surgery on minors, according to a note sent from the White House to the New York Times (https://www.nytimes.com/2024/06/28/health/transgender-surgery-biden.html#:~:text=The%20statement%20followed%20a%20report,treatment%20guidelines%20for%20transgender%20minors.)
- China
- The pressures of health reform on doctors cause many to opt for the private sector. The salary of doctors in China (equivalent to $13,000 per year on average) is lower than that of other Chinese professionals (https://www.economist.com/china/2024/06/27/health-care-reform-is-upending-the-lives-of-chinas-doctors#)
- Cheap versions of anti-obesity drugs in China and India. Companies prepared to make low-cost versions of these drugs, which will expand access to those drugs (https://www.nature.com/articles/d41586-024-02044-x)
- United Kingdom and the National Health Service
- The Lancet analyzes the changes in health necessary as a result of the elections in the United Kingdom. The NHS faces numerous challenges in many areas – from record waiting lists to repeated strikes – resulting in historic levels of dissatisfaction among patients and professionals. As analyzed in the Nuffield Trust, none of the major parties promise a substantial increase in funding (https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)01344-8/fulltext)
- Brazil
- The Supreme Court decriminalizes cannabis. In a process that began in 2015, 8 judges out of 11 of this court decided that the personal use of this drug is not an illicit act (https://www.lemonde.fr/international/article/2024/06/27/le-bresil-decriminalise-la-possession-individuelle-du-cannabis_6244580_3210.html#:~:text=La%20décision%20était%20attendue%20depuis,du%20cannabis%20à%20usage%20personnel.)
- European Union
- They warn that the new European pharmaceutical legislation may discourage the development of medicines for rare diseases (https://diariofarma.com/2024/06/26/la-nueva-legislacion-europea-may-desincentivar-el-desarrollo-de-orphan-drugs)
National health policy
- Central government initiatives
- Health announces the approval of the Action Plan in AP and Community in the last quarter of the year (https://gacetamedica.com/politica/sanidad-anuncia-la-aprobacion-del-plan-de-accion-en-ap-y-community-the-last-quarter-of-the-year/#:~:text=The%20minister%20of%20Health%2C%20Mónica,the%20end%20of%20attract%20y)
- The minister sets a date for the creation of the Urgencias and Emergencies specialty (https://isanidad.com/286958/monica-garcia-asegura-que-la-especialidad-de-urgencias-y-emergencias-se-aprobara-Inthenextweeks/)
- Mónica García defends the Catalan model, in the face of criticism from Junts (https://www.diariomedico.com/medicina/politica/monica-garcia-defiende-modelo-catalan-criticas-junts-proyecto-gestion-publica-directa.html)
- Initiatives and news from the autonomous communities
- Madrid expands the exception to hire non-European doctors in the public sector to all medical specialties. If a position remains unfilled, a non-EU doctor may apply for it, that is, whose medical degree has not been issued by the EU. Madrid is a pioneer in this measure, which bypasses state law (https://www.elespanol.com/madrid/comunidad/20240625/madrid-amplia-excepcion-contratar-publica-medicos-no-europeos-todas-especialidades-sanitary/865413838_0.html#:~:text=With%20la%20cited%20ley%20Omnibus,issued%20u%20homologated%20in%20Spain.)
- The extra 500 euros from Ayuso to hire doctors in rural areas does not work, it only covers 25% of the places (https://www.elespanol.com/madrid/comunidad/20240625/plus-euros-ayuso-contratar-doctors-rural-zones-doesnot-work-only-covers-places/865413919_0.html#:~:text=According to%20has%20informed%20the%20Counseling,and%20Pediatrics%20that%20there%20areavailable.)
- The Heads of Service can now practice privately in Aragon (https://www.redaccionmedica.com/secciones/parlamentarios/los-jefes-de-servicio-de-aragon-ya-trabajon-volver-a-ejercer-en-la-privada-5431#:~:text=PP%20y%20Vox%20sacan%20forward, health%20privada%2C%20in force%20since%202016.)
- Loyalty of the MIRs in Aragon (https://www.consalud.es/formacion/mir/fidelizacion-mir-en-aragon-es-cuidado-plan-ha-elogiado-ministra-sanidad_145876_102.html)
- Health professions
- A summer with 6,000 fewer doctors. The residents will finish later this year, due to the pandemic, and will not be able to fill the vacancies (https://elpais.com/sociedad/2024-06-29/un-verano-con-6000-medicos-menos-la-dificil-x-ray-of-health-on-holidays.html)
- Universal benefit for children from 0 to 3 years old
- The CES calls for a universal benefit for children from 0 to 3 years old that is not conditioned by income. It is assumed that Spain has an “unheard of” problem, which does not correspond to its level of wealth: one in three minors lives at risk of poverty or social exclusion. The problem is especially serious from six months to three years (https://www.elconfidencial.com/economia/2024-06-27/consejo-economico-y-social-pobreza-infantil_3912183/)
- Statements by Félix Lobo
- “It is not true that innovative therapies arrive late in Spain.” We need to know whether it is worth paying the high prices that pharmaceutical companies ask for medicines and health technologies, but we do not have good mechanisms to evaluate this. We need an organization independent of political power with means and prestige. It should be something similar to AIREF or the National Commission of Markets and Competition (CNMC) (https://elpais.com/sociedad/2024-06-28/felix-lobo-economista-de-la-salud-no-itis-true-that-innovative-therapies-arrive-late-in-spain.html)
- Cause of death in Spain
- Tumors become the first cause of death in Spain. 26.6% of deaths in 2023 were related to some type of cancer. It is the first time that this cause surpasses ailments of the circulatory system (https://www.eldiario.es/sociedad/tumores-convierten-primera-causa-muerte-espana_1_11479321.html)
- Fertility rate
- Spain below the OECD fertility rate and very far from the replacement level. We have gone from 3.3 children per woman in 1960 to 1.5 in 2022, below the replacement rate (https://www.consalud.es/profesionales/espana-por-debajo-tasa-fertilidad-ocde-far-away-level-replacement_145818_102.html#)
- Mounjaro arrives in Spain
- Mounjaro, from Lilly, NovoNordisk’s competitor in the treatment of obesity, arrives in Spain at a price of 271 euros/month (https://www.abc.es/salud/superventas-ozempic-adelgazar-competencia-mounjaro -promise-lost-20240624144443-nt.html)
Companies
- International News
- Aging is driving up the exoskeleton market, which will reach $1.5 billion by 2027. The prevalence of cerebrovascular accidents and the growing geriatric population is at the origin of this growth (https://theobjective.com/economia/2024-06-23/aging-shoots-market-exoskeletons/)
- Biotechnology company Alnylam announces positive results in a trial against heart disease (https://www.ft.com/content/cb16cf65-4b80-4027-9478-474d3b47e1e1)
- Novonordisk’s obesity drug Wegovy approved in China (https://www.ft.com/content/66b11f6c-8dcd-47ef-b07f-8eaa37a8d181)
- NovoNordisk invests 4 billion dollars to expand production in the US (https://www.ft.com/content/4ace1c9f-819c-49e3-bd7f-eba03c0f2242)
- Pfizer prepares the launch of eight antitumor drugs to lead the market (https://www.eleconomista.es/salud/noticias/12876897/06/24/pfizer-prepara-el-lanzamiento-de-ocho-antitumorales-para-liderar-el-mercado.html#:~:text=Pfizer%20prepares%20the%20launch%20of%20eight%20antitumor%20to%20lead%20the%20market,-The%20plan%2)
- Abbie needs new blood: 50% of her income comes from medications that are more than 15 years old (https://theobjective.com/economia/2024-06-28/abbvie-necesita-savia-nueva-ingresos-farmacos/# )
- National
- Stada will sell six more therapies in Spain before 2025 (https://www.eleconomista.es/salud/noticias/12884021/06/24/stada-vendera-seis-terapias-mas-en-espana-antes-de-2025.html#:~:text=The%20business%20of%20Stada%20grows,the%20laboratory%20a%20elEconomista.es.)
- The Ribera health group expands its presence in new Autonomous Communities and prepares its landing in Andalusia. The announcement will be made in July (https://www.elespanol.com/invertia/observatorios/sanidad/20240625/grupo-sanitario-ribera-amplia-presencia-nuevas-ccaa-prepara-aterrizaje-andalucia/865413955_0.html)
- Vithas opens a high-performance sports medicine center in its Arturo Soria hospital (https://www.plantadoce.com/empresa/vithas-abre-un-centro-de-medicina-deportiva-de-alto-rendimiento-in-its-center-of-arturo-soria)
- Health in Code increases its turnover by 16%, up to 40 million euros (https://www.plantadoce.com/empresa/health-in-code-aumenta-su-facturacion-un-16-hasta-40-millones-de-euros#:~:text=PlantaTwelve-,Health%20in%20Code%20increases%20its%20billing%20a%2016%25%2C%20up to%2040,suchas%20of%20products%20or%20kits.)
- Grifols paid almost 900,000 euros to doctors for activities unrelated to R&D (https://www.eleconomista.es/salud/noticias/12886877/06/24/grifols-pago-casi-900000-euros-a-spanish-doctors-for-activities-without-relation-with-id.html#:~:text=Health-,Grifols%20paid%20almost%20900.000%20euros%20a%20spanish%20doctors%20for,relation%20co)
- Esteve will invest 100 million euros in building a new production unit in Girona (https://www.eleconomista.es/salud/noticias/12887842/06/24/esteve-inviertera-cien-millones-de-euros-en-una-fabrica.html#:~:text=Esteve%20has%20given%20beginning%20,of%20its%20main%20center%20industrial.)
- Isdin buys Balene and increases its commitment to the oral business (https://www.expansion.com/empresas/2024/06/24/66790d92468aebc9038b4573.html)
- Faes Farma expands the investment to double capacity to 200 million (https://cincodias.elpais.com/companias/2024-06-24/faes-farma-amplia-a-200-millones-la-inversion-para-duplicar -capacity.html)