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7 days in healthcare (May 9th-15th, 2022)

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Summary

From the point of view of biomedicine, the important study published by the journal Science should be highlighted, outlining the most detailed atlas of human cells to date. The discussion about the origin of acute childhood hepatitis continues.

As far as Global Health is concerned, it is found that the United States has reached one million deaths from COVID and Europe two million. A sad milestone.

Regarding international health policy, in relation to COVID, the debate continues on the sustainability of the zero-COVID policy in China. Lockdowns in North Korea, possibly the most opaque country in the world. The debate continues in the United States on the modification of the Roe v Wade sentence. Pronouncements from scientific journals (Nature, The Lancet), as well as from the President of the American Medical Association. The ECDC (European Center for Disease Prevention and Control) stops recommending the use of masks on public transport in Europe.

If we talk about national health policy (Spain), the accumulated incidence of COVID continues to grow. Great debate regarding the announced new Abortion Law. It is more than doubtful that the Law will be approved and, if it is, that it will be complied with, given the large number of controversial elements (registration of conscientious objectors, the obligation that these interventions be carried out in public hospitals, the use of terminology of obstetric violence, etc.). The Ministry of Industry takes out the first tender of the cutting-edge health PERTE. Important editorial in El País on waiting lists, which it presents as a scourge of the SNS.

In the field of companies, the WHO denounces attempts to whiten tobacco companies, by way of presenting themselves as green companies.

Biomedicine

Global Health

International health policy

  • COVID-19

o The Director of the WHO affirms that the zero-covid policy in China is not sustainable (https://www.ft.com/content/9b81b9f0-e13d-4b0a-8bdf-91c97c7d61e7)

o A study says that lifting the “zero COVID” policy in China could mean 1.5 million deaths (https://www.theguardian.com/world/2022/may/11/lifting-zero-covid-policies-in -china-could-risk-16m-deaths-says-study)

o China considers the WHO statement on its zero COVID policy “irresponsible” (https://www.ft.com/content/2e20867b-5f1d-4307-93b0-1d9b07d65e34)

o China renounces organizing the 2023 Asian Soccer Cup, due to the pandemic (https://www.lemonde.fr/international/article/2022/05/14/la-chine-renonce-a-organiser-la- coupe-d-asie-2023-de-football-in-raison-de-la-pandemie-de-covid-19_6126096_3210.html)

o Confinement in North Korea, as the first cases of COVID are confirmed (https://www.ft.com/content/41dec58c-3860-4ae3-86c4-716ffe85dbdd)

o Alert in the state of New York, due to the increase in cases (https://www.nytimes.com/live/2022/05/13/world/covid-19-mandates-vaccine-cases)

  • The debate on abortion continues in the United States

o The pronouncement of medical and scientific journals continues against the annulment of the Roe v Wade ruling in the United States, for reasons of public health and worsening of the health of women and children, particularly those with fewer resources. Editorials in Nature (https://www.nature.com/articles/d41586-022-01249-2) and The Lancet (https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22) 00870-4/fulltext), among others.

o Gerald E. Harmon, President of the AMA, the representation of American doctors, was “deeply concerned” about the impact on reproductive health in the United States of this possible modification (https://www.ama-assn.org/ delivering-care/population-care/why-leaked-abortion-opinion-antithetical-public-health)

o The New York Times assures that the annulment of same-sex marriage could be the next step (https://www.nytimes.com/2022/05/11/us/politics/roe-wade-supreme-court- abortion.html)

o Certain groups try to ban telemedicine prescription of pills that interrupt pregnancy (https://www.ft.com/content/6a3dd70e-8bb9-4727-af4a-4036a660db64)

  • Other themes

o The United States, willing to share vaccine technology with poor countries, says Biden (https://www.ft.com/content/ec6b5b3a-7cff-4aa9-8e68-cba3bbaae06f)

o The European Union Aviation Safety Agency and the European Center for Disease Prevention and Control (ECDC), eliminate the recommendation to use masks in airports and during flights (https://www.larazon.es/ society/20220511/2dur4ogv7zemfkl5bbwmsitpme.html)

o Disposable electronic cigarettes are imposed among adolescents in France (https://www.lemonde.fr/societe/article/2022/05/08/les-cigarettes-electroniques-jetables-s-imposent-parmi-les-adolescents_6125199_3224 .html)

o France will stop requiring a mask on public transport starting next Monday, May 16 (https://www.expansion.com/economia/2022/05/12/627ccd8e468aeb71118b4611.html)

National health policy

  • COVID

o The accumulated incidence continues to rise, growing 13 points since the last measurement and standing at 856.65 cases in the last 14 days per 100,000 inhabitants. The ward occupancy rate is 5.80% and the ICU occupancy rate is 4.07% (https://www.consalud.es/pacientes/especial-coronavirus/covid-19-espana-suma-31036-casos- 321-deceased-ia-uploads-856-points_114645_102.html)

  • Regulatory announcements

o The Government willing to approve next Tuesday, May 17, a new abortion law at the initiative of the Ministry of Equality. The 14-week period for abortion to be considered legal is not modified. Most controversial points: 1. Without permission or information to parents from the age of 16; 2. No to surrogacy; 3. Registration of conscientious objectors; 4. Abortion in public hospitals; 5. Leave due to painful menstruation, outside the regulations of the common disease; 6. The terminology of obstetric violence is maintained (https://www.abc.es/sociedad/abci-no-reforma-sino-ley-aborto-ultima-gobierno-diez-claves-rapidas-202205111920_noticia.html)

o The need to strengthen public healthcare so that it can address the 74,000 abortions that are performed in the private sector (https://elpais.com/sociedad/2022-05-14/la-sanidad-publica-debera-reforzarse-para-asumir -the-74000-abortions-that-now-derives-to-the-private.html)

o The Constitutional Court is preparing a ruling in favor of the 2010 Abortion Law for June, after an appeal by the PP, parked for 12 years (https://www.elconfidencial.com/espana/2022-05-13/constitucional-junio -judgment-favorable-law-abortion_3423623/)

  • Other themes

o The Ministry of Industry is putting out to tender the Vanguard Health PERTE for the pharmaceutical and health products sector (https://www.boe.es/boe/dias/2022/05/07/pdfs/BOE-B-2022-14280 .pdf)

o Important editorial in El País on waiting lists, which it presents as a major problem for the SNS (https://elpais.com/opinion/2022-05-10/largas-listas-de-espera.html)

o War of figures in the strike of medical specialists in Madrid (https://elpais.com/espana/madrid/2022-05-10/primer-dia-de-huelga-indefinida-de-medicos-en-madrid-basta -already-of-temporary.html)

o Castilla y León intends to lower the surgical delay in six months by 21 days (https://www.diariofarma.com/2022/05/11/castilla-y-leon-objetivo-bajar-21-dias-la-demora -surgical-in-6-months)

o The national 024 telephone line for suicide prevention is launched (https://www.larazon.es/sociedad/20220509/cubyq6iicncg3nfm6hieltpxvy.html)

o The SNS Interterritorial Council gives the green light to the Mental Health Plan (https://www.diariofarma.com/2022/05/11/el-cisns-da-luz-verde-al-plan-de-salud-mental -con-practica-unanimidad), which is criticized by the President of the Spanish Society of Psychiatry, saying that “Mental Health needs professionals and intermediate centers, not apps” (https://www.redaccionmedica.com/secciones/psiquiatria /-mental-health-needs-professionals-and-intermediate-centers-no-apps–8807)

o The Ministry publishes the list of 462 strategic medicines, which includes 249 active ingredients (https://www.diariomedico.com/farmacia/industria/estos-son-los-462-medicamentos-estrategicos-para-el-sns. html)

o Private doctors ask insurers to raise their fees, which according to them have been frozen for 32 years (https://theobjective.com/economia/2022-05-15/medicos-privados-honorarios/)

o Andalusia can have up to 8 Faculties of Medicine, after the steps in Jaén and Almería only Huelva remains (https://www.redaccionmedica.com/bisturi/-ocho-facultades-de-medicina-en-una-misma-region –3332), something (the proliferation of Medical Faculties) totally against the approaches of the CEEM (State Confederation of Medical Students) and the Conference of Deans

Companies, employers and other agents of the sector

  • International News

o The WHO asks countries to stop the tobacco companies that try to whitewash their image as a green industry (https://elpais.com/clima-y-medio-ambiente/2022-05-13/la-oms-pide- to-the-countries-that-stop-the-tobacco- companies-that-try-to-clean-up-their-image-as-a-green-industry.html)

o Pfizer will buy the biotech company Biohaven for 11.6 billion dollars (https://www.ft.com/content/ea9bb9bc-b5ec-4278-ab42-1f5f14a1a76f)

  • National News

o Vithas invests 3 million euros in the renovation of emergencies (https://www.plantadoce.com/empresa/vithas-madrid-la-milagrosa-invierte-tres-millones-de-euros-en-la-renovacion- of-your-emergencies.html)

o Vitaldent is committed to dental aesthetics by incorporating 73 Smysecret spaces into its clinics (https://www.plantadoce.com/empresa/vitaldent-apuesta-por-la-estetica-dental-e-incorpora-73-espacios-smysecret-a -your-clinics.html)

o Asisa buys a 600m2 center in Zaragoza (https://www.ondacero.es/programas/en-buenas-manos/asisa-compra-centro-medico-600-zaragoza_20220510627a3bbc64c3c90001106b03.html)

o Hospitales Parque grows in Talavera with a new building for outpatient consultations (https://www.plantadoce.com/empresa/hospitales-parque-crece-en-talavera-de-la-reina-con-un-nuevo-edificio- for-external-queries.html)

o Sanitas, SegurCaixa Adeslas and Línea Directa, the most profitable insurers (https://www.expansion.com/empresas/banca/2022/05/09/627567d7e5fdea58068b45f4.html)

o Novartis will manufacture an oncology drug for the whole world in Barcelona (https://www.eleconomista.es/salud/noticias/11765483/05/22/Novartis-fabricara-en-Zaragoza-un-oncologico-para-todo-el -world-.html)

7 days in healthcare (April 4-10, 2022)

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SUMMARY

From the point of view of biomedicine, it is worth highlighting the fact, highlighted by the journal Nature, that the WHO took more than two years to recognize the airborne transmission of covid. A new generation of vaccines that prevent cancer can make tumors disappear before they appear, according to an article in Science. The natural experiment from South Korea and Hong Kong shows that the “omicron” variant can be fatal in unvaccinated people.

As far as Global Health is concerned, the situation in Ukraine gives us difficult lessons in global health, explains the editor of The Lancet. It should be noted that the black American population already exceeds the white population in mortality from opioids. Until now, deaths from this cause occurred mainly in “non-colleged educated” whites.

Regarding international health policy, the European health agencies (EMA and ECDC) say that it is too early for the second “booster” of the covid vaccine. Ten years of “Choosing Wisely” the revolution in medical practice that tries to minimize worthless or low value health interventions.

If we talk about national health policy (Spain), the appearance of the 2022 Health Barometer (First wave) is important. It should be noted that waiting lists are the main concern of the population; the delay in a high percentage of cases to see a primary care physician; and that the positive perception of the public system decreases, while that of the private system increases. Report on health professionals, which says that within five years there will be a shortage of 9,000 doctors.

In the field of companies, from the international point of view, Moderna’s agreement with the non-profit entity IAVI to apply mRNA technology to various diseases should be highlighted. SpainCares confirms that Spain is not in an advantageous position with regard to health tourism.

BIOMEDICINE

GLOBAL HEALTH

INTERNATIONAL HEALTH POLICY

  • COVID

o The United States donates more than 100 million doses of covid vaccine for children (https://www.ft.com/content/3e5f9359-67a5-4f24-971e-51761119899b)

o Shanghai residents beg for food and medicine as authorities lock down the city (https://www.ft.com/content/3e439a10-860b-4ae6-9070-ad8546da8850)

o Olaf Scholz, German Chancellor, fails in Parliament with his plan to make the vaccine mandatory (https://www.ft.com/content/7d0610bf-3cf9-4edd-a392-e9d97dc9fade)

o COVID deaths rise in the UK, with infections at record highs (https://www.theguardian.com/world/2022/apr/05/covid-related-deaths-rise-england-infections-record-high )

o The European health agencies (EMA and ECDC) say that it is too early for the second covid vaccine “booster” (https://www.nytimes.com/2022/04/06/world/europe/covid-second- booster-europe.html)

  • Other themes

o Ten years of “Choosing Wisely”, which revolutionized medical practice based on recommendations of “do not do”, to reduce low-value health care (https://www.nejm.org/doi/full/10.1056/ NEJMp2200422)

o Life expectancy in the US continues to decline in 2021, despite covid vaccines (https://www.washingtonpost.com/health/2022/04/07/life-expectancy-covid/)

o Oklahoma passes one of the toughest anti-abortion laws in the US, following a Republican strategy (https://www.ft.com/content/cee6a170-fa23-47cb-b554-d457d68f225b)

o Important report by the Nuffield Trust on the recovery of health systems after covid, analyzing the situation in several countries (https://www.nuffieldtrust.org.uk/research/health-system-recovery-from-covid-19- international-lessons-for-the-nhs)

o Great impact in the United Kingdom of the Ockenden Report, on maternity care, with the detection of serious problems, published by the British Government (https://www.gov.uk/government/publications/final-report-of- the-ockenden-review/ockenden-review-summary-of-findings-conclusions-and-essential-actions)

NATIONAL HEALTH POLICY (SPAIN)

  • COVID

o Decrease in the incidence of covid: up to 420.17 cases per 100,000 inhabitants over 60 years of age, according to the new measurement method (https://www.redaccionmedica.com/directo/coronavirus-ultimas-noticias/20220410)

o The mask will no longer be mandatory indoors on April 20 (https://www.elmundo.es/ciencia-y-salud/salud/2022/04/06/624d770121efa0ed708b45bb.html)

o COVID only worries 30% of Spaniards, according to the COSMO Spain study, coordinated by the Carlos III Health Institute (https://www.actasanitaria.com/salud-mental/covid-19-solo-pretrabajo-30 -spanish-two-years-pandemic_2002232_102.html)

  • Other themes

o The 2022 Health Barometer (First wave) appears (https://datos.cis.es/pdf/Es3357mar_A.pdf). Some data of interest: the waiting lists, the worst valued by the Spanish (https://www.lavanguardia.com/vida/20220407/8184215/listas-espera-peor-valorado-espanoles-barometro-sanitario-2022.html ); 55% of patients take more than 7 days to get an appointment with their family doctor (https://www.lavanguardia.com/vida/20220408/8185940/55-pacientes-tarda-mas-7-dias-conseguir- family-doctor-appointment.html); lowers the positive perception of the public system and increases that of the private (https://www.diariofarma.com/2022/04/07/cis-baja-la-percepcion-positiva-del-sistema-publico-y-aumenta-la-de-la-privada)

o Within five years there will be a shortage of almost 9,000 doctors (https://www.lavanguardia.com/vida/20220404/8174200/cinco-anos-faltaran-9000-medicos.html), according to the report “Supply-need for medical specialists 2021- 2035”, prepared by Patricia Barber and Beatriz González López-Valcárcel (https://cgcom.es/sites/default/files//u395/2022informeofertanecesidadespecialistasmedicos2021_2035.pdf)

o “Case of masks” a loot of 2,000 million for the purchase of material during the state of alarm (https://elpais.com/espana/2022-04-10/caso-mascarillas-un-botin-de-2000-millones -in-the-law-of-the-jungle.html)

o WAIT Report: Spain falls in time for access to new medicines (https://www.diariofarma.com/2022/04/06/espana-ha-autorizado-el-53-de-los-farmacos-aprobados -in-europe-between-2017-y-2020), to see the WAIT report: https://www.efpia.eu/media/602652/efpia-patient-wait-indicator-final-250521.pdf

o Published the “Report on the initial budgets of the Public Administrations” (AIREF, April 7, 2022) (https://www.airef.es/wp-content/uploads/2021/04/PRESUPUESTOS-INICIALES/Informe-Ptos -initials-2021-.pdf)

o Spain leads the world consumption of benzodiazepines (https://www.elperiodico.com/es/sociedad/20220402/espana-lidera-consumo-mundial-benzodiazepinas-13438583)

COMPANIES, EMPLOYERS AND OTHER AGENTS IN THE SECTOR

  • International News

o Moderna reaches an agreement with IAVI (non-profit association) to apply mRNA to various diseases (https://www.plantadoce.com/empresa/moderna-llega-a-un-acuerdo-con-iavi-para-aplicar -mRNA-for-various-diseases.html)

o Pfizer buys the British biotech company ReViral for 481 million euros (https://www.expansion.com/empresas/industria/2022/04/08/624fd580468aebc31f8b46bb.html)

  • National News

o David Medina (Spaincares): “In the tourism-health binomial, we are not in the top ranking” (https://www.plantadoce.com/adn/david-medina-spaincares-en-el-binomio-turismo-salud -we-are-not-at-the-top-of-the-ranking.html)

o Savana closes a round of 23 million euros, hand in hand with Conexo Ventures (https://www.plantadoce.com/empresa/savana-cierra-una-ronda-de-23-millones-de-euros-de- the-hand-of-connected-ventures.html)

o Sanitas shoots up sales of health insurance by 47%, with 377,000 new policies (https://cincodias.elpais.com/cincodias/2022/04/07/companias/1649322015_528839.html)

o PharmaMar and CNIO allocate 1.2 million euros to testing breast cancer drugs (https://www.plantadoce.com/empresa/pharma-mar-y-el-cnio-destinan-12-millones-de- euros-to-test-drugs-against-breast-cancer.html)

o Miranza underpins its expansion, reaching 80.6 million euros (https://www.plantadoce.com/empresa/miranza-apuntala-su-expansion-tras-incrementar-sus-ventas-un-35-hasta-806 -millions-of-euros.html)

o Farmasierra celebrates its 25th anniversary, reinforcing R&D (https://www.diariomedico.com/farmacia/industria/empresas/farmasierra-celebra-su-25-aniversario-advancing-towards-a-model-industria-40. html)

o Pfizer will export gene therapies from Spain to America (https://www.eleconomista.es/salud/noticias/11706685/04/22/Pfizer-exportara-a-America-terapias-genicas-desde-Espana.html)

 

7 days in healthcare (January 24-30, 2022)

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Summary

From the point of view of biomedicine, the concern regarding resistance to antibiotics continues, after the extensive report published by The Lancet. This pandemic produces more deaths than AIDS and malaria. New variant of “ómicron” appeared in Denmark.

With regard to global health, the tenth anniversary of the declaration on “Neglected tropical diseases” should be highlighted, which provides an opportunity to reflect on a change in which progress has been made, but much remains to be done. COVAX does not have the capacity to receive more donations in the absence of basic financing for the purchase of syringes and other materials, essential to administer the vaccine.

As for international news, the WHO will publish a plan for the transition of the pandemic to the “control phase” in February. IHI initiative, of the European Union, to create a public/private platform for drug research.

In national news from Spain, the sixth wave seems to be starting to subside in terms of new cases, but still with high mortality. Interesting report promoted by Vitaldent on the public financing of dental care. Biosim highlights the savings potential of biosimilars in 2022. The issue of professional recertification advances, with a leading role for FACME.

In company news, the approval by the EMA of Paxlovid, Pfizer’s antiviral pill against COVID, is important. Also the large expected growth in turnover by COVID vaccine manufacturers in 2022 (29%, compared to 2021). Boom of online psychology platforms

Biomedicine

  • It is time to confront the pandemic of antibiotic resistance, since this resistance causes more deaths than AIDS and malaria. AMR Action Fund, a public/private initiative to develop new antibiotics, is underway (FT, January 28, 22)
  • The new BA.2 omicron, which appeared in Denmark, the stealthy variant of the “‘omicron”, warns the WHO that it may not be detectable with PCR (La Razón, January 25, 22)
  • New research identifies the 4 factors that can favor prolonged covid (NYT, January 25, 22)

Global health

  • 10th anniversary of the London declaration on “Neglected tropical diseases”, much progress has been made. Trachoma, schistosomiasis and visceral leishmaniasis are the most frequent of this type of disease (The Lancet, January 29, 22)
  • Developed countries throw away 61.5 million vaccines for having expired in 2021 (El Español, January 28, 22)
  • World Day against Leprosy, the covid pandemic has silenced it, a disease almost eradicated in Europe but still present in the world (ConSalud, January 30, 22)
  • Lack of funding to buy syringes and other accessories means COVAX cannot accept new doses of vaccines (FT, 25 Jan 22)
  • The United States donated 400 million doses of covid vaccine to 112 countries, according to the White House (The Guardian, January 26, 22)
  • Project Syndicate magazine publishes an analysis (How Much Has the Pandemic Cost?) of the economic impact of the pandemic, based on years of life lost and the value of life in different countries. If the official figure of 5.6 million dead at the end of 2021 is taken, this means 38 trillion (American) dollars or 40% of global GDP; If the estimate of deaths from The Economist (17 million) is taken, we would reach 114 trillion or 120% of global GDP (Project Syndicate, January 27, 22)

International News

  • The WHO will publish in February a plan for the transition of the pandemic to the “control phase” (La Razón, January 24, 22)
  • Notable increase in telemedicine in Medicare (USA) during the pandemic (JAMA, January 25, 22)
  • The British Medical Association recommends the use of FPP3 mask to health professionals who have to deal with patients with viral respiratory disease (BMJ, 21 January 22)
  • The new normal in New Zealand goes from covid 0 to covid acceptance (The Guardian, 26 January 22)
  • An Israeli panel recommends the fourth dose to all adults (FT 25 Jan 22)
  • In Canada, demonstrations against compulsory vaccination (The Guardian, January 30, 22)
  • The European Union launches IHI, a public/private initiative for drug research, as a continuation of the Innovative Medicines Initiative, which was launched in 2008 (Acta Sanitaria, January 26, 22)

National News

  • COVID

o The epidemic curve in Spain consolidates its decline, but experts call for caution (El País, January 29, 22)

o The sixth wave already registers 5,674 deaths from covid and could exceed the sixth before February (El Español, January 27, 22)

o Health and the communities extend the limited capacity at sporting events (El País, January 26, 22)

o The anti-vaccines are responsible for increasing deaths by 32% in the sixth wave, according to Fedea (El Español, January 24, 22)

o Those vaccinated have a hundred times less chance of dying if they become infected (El Mundo, January 28, 22)

o Catalonia abolishes the covid passport (La Razón, January 26, 22)

  • Other issues

o Financing dental health (one of the promises of the PSOE-Unidos Podemos government program) will cost the State 5,423 million euros, according to a study promoted by Vitaldent and presented to the Ministry of Health (El Economista, January 25, 22)

o A third of doctors will retire in the next five years (The Objective, January 28, 22)

o Telemedicine is good for reducing CO2 into the atmosphere, it would reduce 277,120 tons of CO2 in Spain in Primary Care alone, according to the report prepared by “GEN Europe Energy Solutions” (ConSalud, January 28, 22)

o More than 13,000 applicants opt for the 8,200 MIR places in the exam on January 29 (Acta Sanitaria, January 28, 22)

o Biosim puts the savings on biosimilars at 1,048 million euros in 2022 (diariofarma, January 26, 22)

o FACME claims its role in the recertification and creates a specific council, chaired by Cecilio Santander (Diario Médico, January 28, 22)

o ISFAS statement on difficulties in negotiating insurance companies-hospital groups for the coverage of this group (Sanifax, January 24, 22)

Companies, employers and other agents of the sector

  • The EMA approves Paxlovid, Pfizer’s antiviral pill against covid (El Economista, January 27, 22)
  • The large vaccine manufacturers will invoice 75,000 million euros for the covid vaccine this year 2022, this is a 29% jump over the estimate for 2021, according to the consulting firm Airfinity (CincoDías, January 25, 22)
  • Pfizer will produce 120 million doses of its drug against covid in Europe (El Español, January 29, 22)
  • Cinfa leads the market in pharmacies and Novartis in hospitals (CincoDías, January 24, 22)
  • The French group Orpea with problems in its listing due to accusations of mistreatment (FT, January 27, 22)
  • BioNTech begins clinical trial for “ómicron” vaccine (FT, January 25, 22)
  • The business of mental health: boom in online psychology platforms (El Periódico de España, 30 January 22)
  • Mifarma (the leading company in Europe for the online sale of pharmacy and parapharmacy products) reinforces its position in Spain with a new image and online platform (La Razón, January 25, 22)
  • United Imaging Healthcare lands in Spain hand in hand with APR Salud (PlantaDoce, January 25, 22)
  • Sanitas is interested in the purchase of the IMQ (Redacción Médica, January 26, 22)
  • Healthcare Activos continues its expansion and will buy a residence in Ferrol (PlantaDoce, January 21, 22)
  • Corachán becomes stronger in Barcelona with a new center in Sarriá (PlantaDoce, 27 January 22)